{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:44:19Z","timestamp":1757778259563},"reference-count":63,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Immunology"],"published-print":{"date-parts":[[2012,2,1]]},"DOI":"10.1093\/intimm\/dxr106","type":"journal-article","created":{"date-parts":[[2011,12,30]],"date-time":"2011-12-30T03:09:28Z","timestamp":1325214568000},"page":"117-128","source":"Crossref","is-referenced-by-count":10,"title":["Sublingual immunization with adenovirus F protein-based vaccines stimulates protective immunity against botulinum neurotoxin A intoxication"],"prefix":"10.1093","volume":"24","author":[{"given":"S.","family":"Jun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Clapp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Zlotkowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hoyt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Holderness","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Maddaloni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. W.","family":"Pascual","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,12,29]]},"reference":[{"issue":"4 Suppl","key":"2_18785874","doi-asserted-by":"publisher","first-page":"S45","DOI":"10.1038\/nm1213","volume":"11","author":"Holmgren","year":"2005","journal-title":"Nature medicine","ISSN":"http:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"issue":"4","key":"3_30355763","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.4049\/jimmunol.180.4.2504","volume":"180","author":"Li","year":"2008","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"2","key":"4_11011153","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.4049\/jimmunol.166.2.1106","volume":"166","author":"Simmons","year":"2001","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"4","key":"5_23584507","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.4049\/jimmunol.178.4.2370","volume":"178","author":"Ranasinghe","year":"2007","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"10","key":"7_17839944","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1038\/nri1203","volume":"3","author":"Kunkel","year":"2003","journal-title":"Nature reviews. Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1474-1733","issn-type":"print"},{"issue":"5","key":"8_11283540","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.4049\/jimmunol.167.5.2441","volume":"167","author":"Csencsits","year":"2001","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"6","key":"9_16726273","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1172\/JCI119286","volume":"99","author":"Quiding-Jarbrink","year":"1997","journal-title":"Journal of Clinical Investigation","ISSN":"http:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"key":"10_19288829","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/j.0105-2896.2005.00299.x","volume":"206","author":"Bienenstock","year":"2005","journal-title":"Immunological reviews","ISSN":"http:\/\/id.crossref.org\/issn\/0105-2896","issn-type":"print"},{"issue":"12","key":"11_11398977","doi-asserted-by":"publisher","first-page":"7481","DOI":"10.1128\/IAI.69.12.7481-7486.2001","volume":"69","author":"Johansson","year":"2001","journal-title":"Infection and Immunity","ISSN":"http:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"issue":"7","key":"12_16824270","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.1128\/IAI.65.7.2676-2684.1997","volume":"65","author":"Bergquist","year":"1997","journal-title":"Infection and Immunity","ISSN":"http:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"issue":"9","key":"13_38537851","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1086\/491739","volume":"192","year":"2005","journal-title":"Journal of Infectious Diseases","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"issue":"18","key":"14_17786031","doi-asserted-by":"publisher","first-page":"10078","DOI":"10.1128\/JVI.77.18.10078-10087.2003","volume":"77","author":"Lemiale","year":"2003","journal-title":"Journal of Virology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-538X","issn-type":"print"},{"issue":"9","key":"15_10523952","doi-asserted-by":"crossref","first-page":"4778","DOI":"10.4049\/jimmunol.165.9.4778","volume":"165","author":"van Ginkel","year":"2000","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"9","key":"16_18058586","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1056\/NEJMp048006","volume":"350","author":"Couch","year":"2004","journal-title":"New England Journal of Medicine","ISSN":"http:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"9","key":"17_18058591","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1056\/NEJMoa030595","volume":"350","author":"Mutsch","year":"2004","journal-title":"New England Journal of Medicine","ISSN":"http:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"9","key":"19_35605883","doi-asserted-by":"publisher","first-page":"e6999","DOI":"10.1371\/journal.pone.0006999","volume":"4","author":"Lewis","year":"2009","ISSN":"http:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"4","key":"20_10099334","first-page":"622","volume":"56","author":"Spangler","year":"1992","journal-title":"Microbiology and Molecular Biology Reviews","ISSN":"http:\/\/id.crossref.org\/issn\/1092-2172","issn-type":"print"},{"issue":"9","key":"21_17155001","doi-asserted-by":"publisher","first-page":"661","DOI":"10.2165\/00003088-200241090-00003","volume":"41","author":"Zhang","year":"2002","journal-title":"Clinical pharmacokinetics","ISSN":"http:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"key":"22_41485435","first-page":"20","volume":"81","year":"2006","journal-title":"Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"issue":"6","key":"23_22949393","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/01.all.0000246617.41871.40","volume":"6","author":"Passalacqua","year":"2006","journal-title":"Current opinion in allergy and clinical immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1473-6322","issn-type":"print"},{"issue":"1","key":"24_18549487","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/j.1398-9995.2005.00699.x","volume":"60","author":"Wilson","year":"2005","journal-title":"Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"issue":"2","key":"25_22462558","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/j.jaci.2006.05.003","volume":"118","author":"Dahl","year":"2006","journal-title":"Journal of Allergy and Clinical Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1097-6825","issn-type":"print"},{"issue":"6","key":"26_30063097","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1016\/j.jaci.2007.07.046","volume":"120","author":"Didier","year":"2007","journal-title":"Journal of Allergy and Clinical Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1097-6825","issn-type":"print"},{"issue":"1","key":"27_18549514","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1111\/j.1398-9995.2004.00616.x","volume":"60","author":"Agostinis","year":"2005","journal-title":"Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"issue":"12","key":"28_32743692","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1111\/j.1398-9995.2008.01742.x","volume":"63","author":"Agostinis","year":"2008","journal-title":"Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"issue":"3","key":"29_17340163","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1159\/000066779","volume":"129","author":"Grosclaude","year":"2002","journal-title":"International archives of allergy and immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1018-2438","issn-type":"print"},{"issue":"3","key":"30_11061971","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1067\/mai.2001.113525","volume":"107","author":"Frew","year":"2001","journal-title":"Journal of Allergy and Clinical Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1097-6825","issn-type":"print"},{"key":"31_36157225","first-page":"8598","volume":"25","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"issue":"5","key":"32_30340251","doi-asserted-by":"publisher","first-page":"1644","DOI":"10.1073\/pnas.0708684105","volume":"105","year":"2008","journal-title":"PNAS","ISSN":"http:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"12","key":"33_36023103","doi-asserted-by":"publisher","first-page":"7851","DOI":"10.4049\/jimmunol.0803740","volume":"183","year":"2009","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"2","key":"34_8965649","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0163-7258(82)90061-4","volume":"19","author":"Sakaguchi","year":"1982","journal-title":"Pharmacology & therapeutics","ISSN":"http:\/\/id.crossref.org\/issn\/0163-7258","issn-type":"print"},{"issue":"1","key":"35_5513818","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1128\/CMR.3.1.66","volume":"3","author":"Hatheway","year":"1990","journal-title":"Clinical Microbiology Reviews","ISSN":"http:\/\/id.crossref.org\/issn\/0893-8512","issn-type":"print"},{"key":"36_28629298","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1146\/annurev.pa.26.040186.002235","volume":"26","year":"1986","journal-title":"Annual review of pharmacology and toxicology","ISSN":"http:\/\/id.crossref.org\/issn\/1545-4304","issn-type":"print"},{"issue":"3","key":"37_6096480","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1001\/archinte.158.3.221","volume":"129","author":"Shapiro","year":"1998","journal-title":"Annals of Internal Medicine","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"38_28298167","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev.pharmtox.44.101802.121554","volume":"44","year":"2004","journal-title":"Annual review of pharmacology and toxicology","ISSN":"http:\/\/id.crossref.org\/issn\/1545-4304","issn-type":"print"},{"issue":"11","key":"39_17317109","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/S0968-0004(02)02177-1","volume":"27","author":"Turton","year":"2002","journal-title":"Trends in biochemical sciences","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7640","issn-type":"print"},{"issue":"11","key":"40_5780958","doi-asserted-by":"crossref","first-page":"4586","DOI":"10.1128\/IAI.65.11.4586-4591.1997","volume":"65","author":"Kiyatkin","year":"1997","journal-title":"Infection and Immunity","ISSN":"http:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"issue":"8","key":"41_22299755","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.toxicon.2006.02.013","volume":"47","author":"Boles","year":"2006","journal-title":"Toxicon (Oxford)","ISSN":"http:\/\/id.crossref.org\/issn\/1879-3150","issn-type":"print"},{"key":"42_41485436","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1186\/1476-8518-6-5","volume":"6","year":"2008","ISSN":"http:\/\/id.crossref.org\/issn\/1476-8518","issn-type":"print"},{"key":"43_37377346","first-page":"7540","volume":"25","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"key":"44_39007675","first-page":"1052","volume":"21","year":"2003","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"issue":"1","key":"45_23756900","doi-asserted-by":"publisher","first-page":"47","DOI":"10.2174\/187152607780090667","volume":"7","author":"Cai","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1871-5265","issn-type":"print"},{"key":"46_38029985","first-page":"D33","volume":"27","year":"2009","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"issue":"10","key":"47_6166788","doi-asserted-by":"crossref","first-page":"4817","DOI":"10.1128\/IAI.66.10.4817-4822.1998","volume":"66","author":"Byrne","year":"1998","journal-title":"Infection and Immunity","ISSN":"http:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"issue":"3","key":"48_29958597","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1128\/IAI.01025-07","volume":"76","year":"2008","journal-title":"Infection and Immunity","ISSN":"http:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"key":"49_41485437","first-page":"1855","volume":"18","year":"2000","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"key":"50_41485438","first-page":"8843","volume":"25","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1873-2518","issn-type":"print"},{"issue":"1-2","key":"51_10499541","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0014-5793(00)01954-2","volume":"482","author":"Ginalski","year":"2000","journal-title":"FEBS Letters","ISSN":"http:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"8","key":"52_10426851","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/78005","volume":"7","author":"Swaminathan","year":"2000","journal-title":"Nature structural biology","ISSN":"http:\/\/id.crossref.org\/issn\/1072-8368","issn-type":"print"},{"key":"53_37597883","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/1471-2172-11-36","volume":"11","author":"Clapp","year":"2010","journal-title":"BMC immunology [electronic resource]","ISSN":"http:\/\/id.crossref.org\/issn\/1471-2172","issn-type":"print"},{"issue":"1","key":"54_39209580","doi-asserted-by":"publisher","first-page":"e16532","DOI":"10.1371\/journal.pone.0016532","volume":"6","author":"Staats","year":"2011","ISSN":"http:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"8","key":"55_22644530","doi-asserted-by":"crossref","first-page":"5524","DOI":"10.4049\/jimmunol.177.8.5524","volume":"177","author":"Maddaloni","year":"2006","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"12","key":"56_37247447","doi-asserted-by":"publisher","first-page":"7144","DOI":"10.4049\/jimmunol.0902739","volume":"184","year":"2010","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"5","key":"57_11067577","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.4049\/jimmunol.166.5.3114","volume":"166","author":"Kato","year":"2001","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"10","key":"58_17320493","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.4049\/jimmunol.169.10.5649","volume":"169","author":"Csencsits","year":"2002","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"1","key":"59_11204583","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4049\/jimmunol.167.1.407","volume":"167","author":"Pascual","year":"2001","journal-title":"The Journal of Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"60_41485656","first-page":"S16-13-9","volume":"24","year":"1997","journal-title":"Seminars in oncology","ISSN":"http:\/\/id.crossref.org\/issn\/0093-7754","issn-type":"print"},{"issue":"1","key":"61_17709469","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1067\/mai.2003.1607","volume":"112","author":"Allam","year":"2003","journal-title":"Journal of Allergy and Clinical Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/1097-6825","issn-type":"print"},{"issue":"7","key":"62_18258492","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1111\/j.1365-2222.2004.01984.x","volume":"34","author":"von Bubnoff","year":"2004","journal-title":"Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0954-7894","issn-type":"print"},{"issue":"2","key":"63_21427456","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/j.1398-9995.2006.01002.x","volume":"61","author":"Moingeon","year":"2006","journal-title":"Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"key":"64_40332260","doi-asserted-by":"crossref","first-page":"794","DOI":"10.4161\/hv.9420","volume":"5","year":"2009","journal-title":"HUM VACCINE"},{"key":"65_34223184","first-page":"955","volume":"82","year":"2000","ISSN":"http:\/\/id.crossref.org\/issn\/1638-6183","issn-type":"print"},{"key":"66_41485440","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.idc.2006.02.003","volume":"20","year":"2006","journal-title":"INFECT CLIN NORTH AM"}],"container-title":["International Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/intimm\/article-pdf\/24\/2\/117\/2080754\/dxr106.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T20:38:35Z","timestamp":1593463115000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/intimm\/article-lookup\/doi\/10.1093\/intimm\/dxr106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,29]]},"references-count":63,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2012,2,1]]},"published-print":{"date-parts":[[2012,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/intimm\/dxr106","relation":{},"ISSN":["0953-8178","1460-2377"],"issn-type":[{"value":"0953-8178","type":"print"},{"value":"1460-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,29]]}}}