{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:05:53Z","timestamp":1792785953486,"version":"4.5.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T00:00:00Z","timestamp":1537833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Spanish Health Research Fund"},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PI16\/00816"],"award-info":[{"award-number":["PI16\/00816"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PI16\/00971"],"award-info":[{"award-number":["PI16\/00971"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the non-adherence to the primary care \u2018do not do\u2019 recommendations (DNDs) and their likelihood to cause harm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Delphi study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Spanish National Health System.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 128 professionals were recruited (50 general practitioners [GPs], 28 pediatricians [PEDs], 31 nurses who care for adult patients [RNs] and 19 pediatric nurses [PNs]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>A selection of 27 DNDs directed at GPs, 8 at PEDs, 9 at RNs and 4 at PNs were included in the Delphi technique. A 10-point scale was used to assess whether a given practice was still present and the likelihood of it causing of an adverse event.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measure<\/jats:title>\n                    <jats:p>Impact calculated by multiplying an event\u2019s frequency and likelihood to cause harm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 100 professionals responded to wave 1 (78% response rate) and 97 of them to wave 2 (97% response rate). In all, 22% (6\/27) of the practices for GPs, 12% (1\/8) for PEDs, 33% (3\/9) for RNs and none for PNs were cataloged as frequent. A total of 37% (10\/27) of these practices for GPs, 25% (2\/8) for PEDs, 33% (3\/9) for RNs and 25% (1\/4) for PNs were considered as potential causes of harm. Only 26% (7\/27) of the DNDs for GPs showed scores equal to or higher than 36 points. The impact measure was higher for ordering benzodiazepines to treat insomnia, agitation or delirium in elderly patients (mean = 57.8, SD = 25.3).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Low-value and potentially dangerous practices were identified; avoiding these could improve care quality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/intqhc\/mzy203","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T07:26:33Z","timestamp":1535700393000},"page":"519-526","source":"Crossref","is-referenced-by-count":12,"title":["Low-value clinical practices and harm caused by non-adherence to \u2018do not do\u2019 recommendations in primary care in Spain: a Delphi study"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6497-083X","authenticated-orcid":false,"given":"Jos\u00e9 Joaqu\u00edn","family":"Mira","sequence":"first","affiliation":[{"name":"Alicante-Sant Joan Health District, Conseller\u00eda de Sanidad, Alicante, Spain"},{"name":"Universidad Miguel Hern\u00e1ndez de Elche, Elche, Spain"},{"name":"REDISEC, Red de Servicios de Salud Orientados a Enfermedades Cr\u00f3nicas, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Caro Mendivelso","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Qualitat i Avaluaci\u00f3 Sanit\u00e0ries de Catalunya (AQuAS), Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Carrillo","sequence":"additional","affiliation":[{"name":"Universidad Miguel Hern\u00e1ndez de Elche, Elche, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Gonz\u00e1lez de Dios","sequence":"additional","affiliation":[{"name":"Hospital General Universitario de Alicante, Conseller\u00eda de Sanidad, Alicante, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Raras (CIBERER), Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guadalupe","family":"Olivera","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos, Servicio Madrile\u00f1o de Salud, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pastora","family":"P\u00e9rez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Observatorio para la Seguridad del Paciente, Agencia de Calidad Sanitaria de Andaluc\u00eda, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Nebot","sequence":"additional","affiliation":[{"name":"Centro de Salud Fuente de San Luis, Dr. Peset Health District, Conseller\u00eda de Sanidad, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Silvestre","sequence":"additional","affiliation":[{"name":"Servicio de Efectividad y Seguridad Asistencial, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3757-8565","authenticated-orcid":false,"given":"Yolanda","family":"Agra","sequence":"additional","affiliation":[{"name":"Area de Seguridad del Paciente, Ministerio de Sanidad, Consumo y Bienestar Social, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Servicio de Efectividad y Seguridad Asistencial, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 L","family":"Valencia-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, Servicio Madrile\u00f1o de Salud, Madrid, Spain"},{"name":"Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria (IRYCIS), Madrid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Ariztegui","sequence":"additional","affiliation":[{"name":"Servicio de Efectividad y Seguridad Asistencial, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Aranaz","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, Servicio Madrile\u00f1o de Salud, Madrid, Spain"},{"name":"Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria (IRYCIS), Madrid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"SOBRINA Research Team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,9,25]]},"reference":[{"key":"2019111908102071600_mzy203C1","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1056\/NEJMp0911423","article-title":"Medicine\u2019s ethical responsibility for health reform\u2014the Top Five List","volume":"362","author":"Brody","year":"2010","journal-title":"N Engl J Med"},{"key":"2019111908102071600_mzy203C2","author":"National Institute for Health and Care Excellence (NICE)"},{"key":"2019111908102071600_mzy203C3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.cali.2015.02.003","article-title":"Resultados de la aplicabilidad de las \u00abdo not do recommendations\u00bb del National Institute for Health and Care Excellence en un hospital de alta complejidad","volume":"30","author":"Martin","year":"2015","journal-title":"Rev Calid Asist"},{"key":"2019111908102071600_mzy203C4","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/intqhc\/mzx135","article-title":"Lean Management to support Choosing Wisely in healthcare: the first evidence from a systematic literature review","volume":"29","author":"Crema","year":"2017","journal-title":"Int J Qual Health Care"},{"key":"2019111908102071600_mzy203C5","author":"The ABIM Foundation"},{"key":"2019111908102071600_mzy203C6","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1097\/ACM.0000000000000270","article-title":"Engaging physicians and consumers in conversations about treatment overuse and waste: a short history of the Choosing Wisely Campaign","volume":"89","author":"Wolfson","year":"2014","journal-title":"Acad Med"},{"key":"2019111908102071600_mzy203C7","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12875-017-0667-4","article-title":"Medical overuse and quaternary prevention in primary care\u2014a qualitative study with general practitioners","volume":"18","author":"Alber","year":"2017","journal-title":"BMC Fam Pract"},{"key":"2019111908102071600_mzy203C8","doi-asserted-by":"crossref","first-page":"e021339","DOI":"10.1136\/bmjopen-2017-021339","article-title":"Drivers and strategies for avoiding overuse. A cross-sectional study to explore the experience of Spanish primary care providers handling uncertainty and patients\u2019 requests","volume":"8","author":"Mira","year":"2018","journal-title":"BMJ Open"},{"key":"2019111908102071600_mzy203C9","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1001\/archinternmed.2011.231","article-title":"The \u2018top 5\u2019 lists in primary care: meeting the responsibility of professionalism","volume":"171","author":"Good Stewardship Working Group","year":"2011","journal-title":"Arch Intern Med"},{"key":"2019111908102071600_mzy203C10","first-page":"85","article-title":"Italy\u2019s slow medicine: a new paradigm in medicine","volume":"106","author":"Bonaldi","year":"2015","journal-title":"Recenti Prog Med"},{"key":"2019111908102071600_mzy203C11","volume-title":"Recomendaciones \u00abNO HACER","author":"Grupo de Trabajo de la semFYC para el proyecto Recomendaciones \u00abNo hacer\u00bb","year":"2014"},{"key":"2019111908102071600_mzy203C12","volume-title":"Recomendaciones \u00abNO HACER\u00bb 2.\u00aa Parte","author":"Grupo de Trabajo de la semFYC para el proyecto Recomendaciones \u00abNo hacer\u00bb","year":"2015"},{"key":"2019111908102071600_mzy203C13","volume-title":"15 Recomendaciones \u00abNo hacer\u00bb en urgencias","author":"Grupo de Trabajo de la semFYC para el proyecto Recomendaciones \u00abNo hacer\u00bb","year":"2016"},{"key":"2019111908102071600_mzy203C14","author":"Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda (AEP)","year":"2014"},{"key":"2019111908102071600_mzy203C15","article-title":"Identificaci\u00f3n y priorizaci\u00f3n de pr\u00e1cticas cl\u00ednicas de poco valor: los profesionales de atenci\u00f3n primaria deciden","author":"Caro-Mendivelso","year":"2017","journal-title":"Aten Primaria"},{"key":"2019111908102071600_mzy203C16","author":"Essencial"},{"key":"2019111908102071600_mzy203C17","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1001\/jamainternmed.2015.5441","article-title":"Early trends among seven recommendations from the Choosing Wisely Campaign","volume":"175","author":"Rosenberg","year":"2015","journal-title":"JAMA Intern Med"},{"key":"2019111908102071600_mzy203C18","author":"PerryUndem Research\/Communication"},{"key":"2019111908102071600_mzy203C19","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.gaceta.2016.06.007","article-title":"Actitudes de los m\u00e9dicos hacia el problema de las pruebas y los procedimientos innecesarios","volume":"30","author":"Zambrana-Garc\u00eda","year":"2016","journal-title":"Gac Sanit"},{"key":"2019111908102071600_mzy203C20","article-title":"Grado de conocimiento entre m\u00e9dicos de familia, pediatras y enfermer\u00eda de la campa\u00f1a Compromiso por la Calidad y de recomendaciones No hacer para Atenci\u00f3n Primaria","author":"Mira","year":"2018","journal-title":"An Sist Sanit Navar"},{"key":"2019111908102071600_mzy203C21","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1186\/s13104-016-2103-6","article-title":"A survey of primary care patients\u2019 readiness to engage in the de-adoption practices recommended by Choosing Wisely","volume":"9","author":"Silverstein","year":"2016","journal-title":"BMC Res Notes"},{"key":"2019111908102071600_mzy203C22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1080\/13814788.2017.1395018","article-title":"How do Swiss general practitioners agree with and report adhering to a top-five list of unnecessary tests and treatments? Results of a cross-sectional survey","volume":"24","author":"Kevin","year":"2018","journal-title":"Eur J Gen Pract"},{"key":"2019111908102071600_mzy203C23","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/s11606-016-3853-5","article-title":"Perceived barriers to implementing individual Choosing Wisely\u00ae Recommendations in two national surveys of primary care providers","volume":"32","author":"Zikmund-Fisher","year":"2016","journal-title":"J Gen Intern Med"},{"key":"2019111908102071600_mzy203C24","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1007\/s11606-014-2898-6","article-title":"Controlling health costs: physician responses to patient expectations for medical care","volume":"29","author":"Sabbatini","year":"2014","journal-title":"J Gen Intern Med"},{"key":"2019111908102071600_mzy203C25","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1377\/hlthaff.2016.1263","article-title":"Small decline in low-value back imaging associated with the \u2018Choosing Wisely\u2019 Campaign, 2012\u201314","volume":"36","author":"Hong","year":"2017","journal-title":"Health Aff (Millwood)"},{"key":"2019111908102071600_mzy203C26","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1080\/13814788.2017.1395018","article-title":"How do Swiss general practitioners agree with and report adhering to a top-five list of unnecessary tests and treatments? Results of a cross-sectional survey","volume":"24","author":"Selby","year":"2018","journal-title":"Eur J Gen Pract"},{"key":"2019111908102071600_mzy203C27","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.ejim.2017.09.011","article-title":"Diagnostic process-how to do it right? The SMART medicine initiative","volume":"46","author":"Zalts","year":"2017","journal-title":"Eur J Intern Med"},{"key":"2019111908102071600_mzy203C28","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1001\/jamainternmed.2016.8254","article-title":"Clinicians\u2019 expectations of the benefits and harms of treatments, screening, and tests","volume":"177","author":"Hoffmann","year":"2017","journal-title":"JAMA Intern Med"},{"key":"2019111908102071600_mzy203C29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40258-014-0126-5","article-title":"Systematic overuse of healthcare services: a conceptual model","volume":"13","author":"Nassery","year":"2015","journal-title":"Appl Health Econ Health Policy"},{"key":"2019111908102071600_mzy203C30","doi-asserted-by":"crossref","first-page":"g2975","DOI":"10.1136\/bmj.g2975","article-title":"The human cost of overuse","volume":"348","author":"Gibson","year":"2014","journal-title":"Br Med J"},{"key":"2019111908102071600_mzy203C31","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1001\/jama.2017.0698","article-title":"Is excessive resource utilization an adverse event?","volume":"317","author":"Zapata","year":"2017","journal-title":"J Am Med Assoc"},{"key":"2019111908102071600_mzy203C32","author":"Mira"},{"key":"2019111908102071600_mzy203C33","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0212-6567(04)78902-7","article-title":"Investigaci\u00f3n cualitativa: una alternativa tambi\u00e9n v\u00e1lida","volume":"34","author":"Mira","year":"2004","journal-title":"Aten Primaria"},{"key":"2019111908102071600_mzy203C34","author":"World Health Organization","year":"2009"},{"key":"2019111908102071600_mzy203C35","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1001\/jama.280.11.1000","article-title":"The urgent need to improve health care quality. Institute of Medicine National Roundtable on Health Care Quality","volume":"280","author":"Chassin","year":"1998","journal-title":"J Am Med Assoc"},{"key":"2019111908102071600_mzy203C36","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1001\/archinternmed.2010.90","article-title":"Less is more: how less health care can result in better health","volume":"170","author":"Grady","year":"2010","journal-title":"Arch Intern Med"},{"key":"2019111908102071600_mzy203C37","author":"Otte","year":"2018"},{"key":"2019111908102071600_mzy203C38","doi-asserted-by":"crossref","first-page":"540707","DOI":"10.1155\/2013\/540707","article-title":"Danish general practitioners\u2019 use of prostate-specific antigen in opportunistic screening for prostate cancer: a survey comprising 174 GPs","volume":"2013","author":"Jessen","year":"2013","journal-title":"Inter J Family Med"},{"key":"2019111908102071600_mzy203C39","first-page":"401","article-title":"Priorizaci\u00f3n de actividades cl\u00ednicas no recomendadas en Atenci\u00f3n Primaria","volume":"40","author":"Garc\u00eda-Moch\u00f3n","year":"2017","journal-title":"An Sist Sanit Navar"},{"key":"2019111908102071600_mzy203C40","first-page":"337","article-title":"Physician perceptions of Choosing Wisely and drivers of overuse","volume":"22","author":"Colla","year":"2016","journal-title":"Am J Manag Care"},{"key":"2019111908102071600_mzy203C41","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1001\/archinternmed.2011.437","article-title":"Too little? Too much? Primary care physicians\u2019 views on US Health Care","volume":"171","author":"Sirovich","year":"2011","journal-title":"Arch Intern Med"},{"key":"2019111908102071600_mzy203C42","doi-asserted-by":"crossref","first-page":"e726","DOI":"10.1503\/cmaj.120568","article-title":"Training family physicians in shared decision-making to reduce the overuse of antibiotics in acute respiratory infections: a cluster randomized trial","volume":"184","author":"L\u00e9gar\u00e9","year":"2012","journal-title":"CMAJ"},{"key":"2019111908102071600_mzy203C43","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1471-2431-9-69","article-title":"Why do paediatricians prescribe antibiotics? Results of an Italian regional Project","volume":"9","author":"Moro","year":"2009","journal-title":"BMC Pediatr"},{"key":"2019111908102071600_mzy203C44","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.jclinepi.2014.05.020","article-title":"A review of clinical practice guidelines found that they were often based on evidence of uncertain relevance to primary care patients","volume":"67","author":"Steel","year":"2014","journal-title":"J Clin Epidemiol"},{"key":"2019111908102071600_mzy203C45","doi-asserted-by":"crossref","first-page":"346","DOI":"10.12788\/jhm.2738","article-title":"A practical framework for understanding and reducing medical overuse: conceptualizing overuse through the patient-clinician interaction","volume":"12","author":"Morgan","year":"2017","journal-title":"J Hosp Med"},{"key":"2019111908102071600_mzy203C46","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1001\/jamainternmed.2017.4361","article-title":"2017 Update on medial overuse. a systematic review","volume":"178","author":"Morgan","year":"2018","journal-title":"JAMA Intern Med"},{"key":"2019111908102071600_mzy203C47","first-page":"31","article-title":"Are Spanish physicians ready to take advantage of the Internet?","volume":"40","author":"Lorenzo","year":"2004","journal-title":"World Hosp Health Serv"},{"key":"2019111908102071600_mzy203C48","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1157\/13071940","article-title":"Evaluaci\u00f3n de la demanda derivada en atenci\u00f3n primaria","volume":"35","author":"de Prado-Prieto","year":"2005","journal-title":"Aten Primaria"}],"container-title":["International Journal for Quality in Health Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/intqhc\/article-pdf\/31\/7\/519\/30989377\/mzy203.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/intqhc\/article-pdf\/31\/7\/519\/30989377\/mzy203.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T08:10:41Z","timestamp":1574151041000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/intqhc\/article\/31\/7\/519\/5106598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,25]]},"references-count":48,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,9,25]]},"published-print":{"date-parts":[[2019,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/intqhc\/mzy203","relation":{},"ISSN":["1353-4505","1464-3677"],"issn-type":[{"value":"1353-4505","type":"print"},{"value":"1464-3677","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,8]]},"published":{"date-parts":[[2018,9,25]]}}}