{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:51:04Z","timestamp":1791273064777,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":241,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32560262"],"award-info":[{"award-number":["32560262"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Basic Research Program of Yunnan Province","award":["202401AS070039"],"award-info":[{"award-number":["202401AS070039"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,14]]},"abstract":"<jats:title>Synopsis<\/jats:title>\n                  <jats:p>Low temperature is a major environmental constraint for animals inhabiting cold plateau regions because it increases thermoregulatory energy demand and can disrupt oxidative balance. We examined physiological responses of two sympatric plateau rodents, Eothenomys miletus and Apodemus chevrieri, during 28 days of cold exposure (5\u00b0C\u00a0\u00b1\u00a01\u00b0C) relative to control conditions (25\u00b0C\u00a0\u00b1\u00a01\u00b0C). Both species increased resting metabolic rate (RMR) and food intake and showed lower body mass under cold conditions. Cold exposure also increased liver mass and induced digestive-tract remodeling, with more extensive changes in E. miletus than A. chevrieri. Activities of the antioxidant enzyme superoxide dismutase (SOD) and catalase (CAT), together with the oxidative stress markers malondialdehyde (MDA) and hydrogen peroxide (H2O2), changed in a tissue- and species-specific manner. Correlation and principal component analyses further indicated different patterns of oxidative regulation in the two species. Eothenomys miletus showed a comparatively dense inter-organ correlation structure centered on CAT, whereas A. chevrieri showed fewer significant inter-organ associations. Thus, the two rodents share a broad metabolic response to sustained cold exposure but differ in the organ-level organization of oxidative balance.<\/jats:p>","DOI":"10.1093\/iob\/obag051","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:08:22Z","timestamp":1788048502000},"source":"Crossref","is-referenced-by-count":0,"title":["Effects of Cold Exposure on Energy Metabolism and Oxidative Stress in Two Plateau Rodents"],"prefix":"10.1093","volume":"8","author":[{"given":"D","family":"Hou","sequence":"first","affiliation":[{"name":"School of Life Sciences, Yunnan Normal University , Kunming 650500 ,","place":["China"]},{"name":"College of Life Science and Technology, Inner Mongolia Normal University , Hohhot 010022 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Hebei University , Baoding 071000 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