{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:09:44Z","timestamp":1793412584698,"version":"4.5.0"},"reference-count":79,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T00:00:00Z","timestamp":1716595200000},"content-version":"vor","delay-in-days":145,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32170108"],"award-info":[{"award-number":["32170108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42306113"],"award-info":[{"award-number":["42306113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42188102"],"award-info":[{"award-number":["42188102"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017549","name":"Science and Technology Innovation 2025 Major Project of Ningbo City","doi-asserted-by":"publisher","award":["2022Z189"],"award-info":[{"award-number":["2022Z189"]}],"id":[{"id":"10.13039\/501100017549","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Independent Research Projects of Southern Marine Science and Engineering Guangdong Laboratory","award":["SML2021SP204"],"award-info":[{"award-number":["SML2021SP204"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>As diazotrophic cyanobacteria of tremendous biomass, Trichodesmium continuously provide a nitrogen source for carbon-fixing cyanobacteria and drive the generation of primary productivity in marine environments. However, ocean iron deficiencies limit growth and metabolism of Trichodesmium. Recent studies have shown the co-occurrence of Trichodesmium and siderophore-producing Synechococcus in iron-deficient oceans, but whether siderophores secreted by Synechococcus can be used by Trichodesmium to adapt to iron deficiency is not clear. We constructed a mutant Synechococcus strain unable to produce siderophores to explore this issue. Synechococcus filtrates with or without siderophores were added into a Trichodesmium microbial consortium consisting of Trichodesmium erythraeum IMS 101 as the dominant microbe with chronic iron deficiency. By analyzing the physiological phenotype, metagenome, and metatranscriptome, we investigated the interactions between the nitrogen-fixing cyanobacterium Tricodesmium and siderophore-producing cyanobacterium Synechococcus under conditions of iron deficiency. The results indicated that siderophores secreted by Synechococcus are likely to chelate with free iron in the culture medium of the Trichodesmium consortium, reducing the concentration of bioavailable iron and posing greater challenges to the absorption of iron by Trichodesmium. These findings revealed the characteristics of iron-competitive utilization between diazotrophic cyanobacteria and siderophore-producing cyanobacteria, as well as potential interactions, and provide a scientific basis for understanding the regulatory effects of nutrient limitation on marine primary productivity.<\/jats:p>","DOI":"10.1093\/ismeco\/ycae072","type":"journal-article","created":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T07:50:38Z","timestamp":1716623438000},"source":"Crossref","is-referenced-by-count":8,"title":["Interactions between the nitrogen-fixing cyanobacterium\n                    <i>Trichodesmium<\/i>\n                    and siderophore-producing cyanobacterium\n                    <i>Synechococcus<\/i>\n                    under iron limitation"],"prefix":"10.1093","volume":"4","author":[{"given":"Xumei","family":"Sun","sequence":"first","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"},{"name":"Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) , 1 Jintang Road, Zhuhai, Guangdong, 519000 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Central China Normal University , 152 Luoyu Road, Wuhan, Hubei, 430079 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengwen","family":"Yong","sequence":"additional","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hansheng","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangqing","family":"Li","sequence":"additional","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"},{"name":"Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) , 1 Jintang Road, Zhuhai, Guangdong, 519000 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Marine Sciences, Ningbo University , 818 Fenghua Road, Ningbo, Zhejiang, 315211 , People\u2019s Republic of China"},{"name":"Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) , 1 Jintang Road, Zhuhai, Guangdong, 519000 , People\u2019s Republic of China"},{"name":"School of Life Sciences, Central China Normal University , 152 Luoyu Road, Wuhan, Hubei, 430079 , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,25]]},"reference":[{"key":"2024061320501716000_ref1","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.3389\/fmicb.2020.01659","article-title":"High light induced alka(e)ne biodegradation for lipid and redox homeostasis in cyanobacteria","volume":"11","author":"Qiao","year":"2020","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref2","doi-asserted-by":"crossref","first-page":"9824","DOI":"10.1073\/pnas.1307701110","article-title":"Present and future global distributions of the marine cyanobacteria Prochlorococcus and Synechococcus","volume":"110","author":"Flombaum","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"2024061320501716000_ref3","doi-asserted-by":"crossref","first-page":"E3365","DOI":"10.1073\/pnas.1524865113","article-title":"Delineating ecologically significant taxonomic units from global patterns of marine picocyanobacteria","volume":"113","author":"Farrant","year":"2016","journal-title":"Proc Natl Acad Sci USA"},{"key":"2024061320501716000_ref4","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/s41396-018-0287-6","article-title":"Parallel phylogeography of Prochlorococcus and Synechococcus","volume":"13","author":"Kent","year":"2019","journal-title":"ISME J."},{"key":"2024061320501716000_ref5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/nrmicro2386","article-title":"Microbial production of recalcitrant dissolved organic matter: long-term carbon storage in the global ocean","volume":"8","author":"Jiao","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"2024061320501716000_ref6","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1126\/science.1118052","article-title":"Niche partitioning among Prochlorococcus ecotypes along oceanscale environmental gradients","volume":"311","author":"Johnson","year":"2006","journal-title":"Science"},{"key":"2024061320501716000_ref7","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/s41396-017-0041-5","article-title":"Coordinated gene expression between Trichodesmium and its microbiome over day-night cycles in the North Pacific subtropical gyre","volume":"12","author":"Frischkorn","year":"2018","journal-title":"ISME J."},{"key":"2024061320501716000_ref8","doi-asserted-by":"crossref","first-page":"eaay9514","DOI":"10.1126\/science.aay9514","article-title":"Changing perspectives in marine nitrogen fixation","volume":"368","author":"Zehr","year":"2020","journal-title":"Science"},{"key":"2024061320501716000_ref9","doi-asserted-by":"crossref","first-page":"eabl7564","DOI":"10.1126\/sciadv.abl7564","article-title":"Nutrient regulation of biological nitrogen fixation across the tropical western North Pacific","volume":"8","author":"Wen","year":"2022","journal-title":"Sci Adv"},{"key":"2024061320501716000_ref10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nrmicro2594","article-title":"Emerging patterns of marine nitrogen fixation","volume":"9","author":"Sohm","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"2024061320501716000_ref11","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1574-6976.2012.00352.x","article-title":"Trichodesmium-a widespread marine cyanobacterium with unusual nitrogen fixation properties","volume":"37","author":"Bergman","year":"2013","journal-title":"FEMS Microbiol Rev"},{"key":"2024061320501716000_ref12","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1038\/s41467-021-24299-y","article-title":"Global distribution patterns of marine nitrogen-fixers by imaging and molecular methods","volume":"12","author":"Pierella Karlusich","year":"2021","journal-title":"Nat Commun"},{"key":"2024061320501716000_ref13","first-page":"1","volume-title":"Nitrogen in the Marine Environment","author":"Gruber","year":"2008","edition":"2nd"},{"key":"2024061320501716000_ref14","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/s41396-019-0514-9","article-title":"Distinct nitrogen cycling and steep chemical gradients in Trichodesmium colonies","volume":"14","author":"Klawonn","year":"2020","journal-title":"ISME J."},{"key":"2024061320501716000_ref15","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1038\/nclimate3147","article-title":"Marine phytoplankton and the changing ocean iron cycle","volume":"6","author":"Hutchins","year":"2016","journal-title":"Nat Clim Change."},{"key":"2024061320501716000_ref16","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1046\/j.1529-8817.2001.00080.x","article-title":"Nutrient controls on nitrogen uptake and metabolism by natural populations and cultures of Trichodesmium (cyanobacteria)","volume":"37","author":"Mulholland","year":"2001","journal-title":"J Phycol"},{"key":"2024061320501716000_ref17","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1038\/ngeo667","article-title":"Large-scale distribution of Atlantic nitrogen fixation controlled by iron availability","volume":"2","author":"Mark Moore","year":"2009","journal-title":"Nat Geosci"},{"key":"2024061320501716000_ref18","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1038\/ismej.2017.49","article-title":"The Trichodesmium consortium: conserved heterotrophic co-occurrence and genomic signatures of potential interactions","volume":"11","author":"Lee","year":"2017","journal-title":"ISME J"},{"key":"2024061320501716000_ref19","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/ismej.2014.186","article-title":"A novel cohabitation between two diazotrophic cyanobacteria in the oligotrophic ocean","volume":"9","author":"Momper","year":"2015","journal-title":"ISME ."},{"key":"2024061320501716000_ref20","doi-asserted-by":"crossref","first-page":"eabf4792","DOI":"10.1126\/sciadv.abf4792","article-title":"Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference","volume":"8","author":"Nair","year":"2022","journal-title":"Sci Adv"},{"key":"2024061320501716000_ref21","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nature02550","article-title":"Iron and phosphorus co-limit nitrogen fixation in the eastern tropical North Atlantic","volume":"429","author":"Mills","year":"2004","journal-title":"Nature"},{"key":"2024061320501716000_ref22","doi-asserted-by":"crossref","first-page":"12081","DOI":"10.1038\/ncomms12081","article-title":"Mechanisms of increased Trichodesmium fitness under iron and phosphorus co-limitation in the present and future ocean","volume":"7","author":"Walworth","year":"2016","journal-title":"Nat Commun"},{"key":"2024061320501716000_ref23","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pocean.2018.08.001","article-title":"Environmental and nutrient controls of marine nitrogen fixation","volume":"167","author":"Li","year":"2018","journal-title":"Prog Oceanogr"},{"key":"2024061320501716000_ref24","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/s41558-018-0216-8","article-title":"Ocean warming alleviates iron limitation of marine nitrogen fixation","volume":"8","author":"Jiang","year":"2018","journal-title":"Nat Clim Change"},{"key":"2024061320501716000_ref25","doi-asserted-by":"crossref","first-page":"624","DOI":"10.3389\/fmicb.2018.00624","article-title":"An integrated response of Trichodesmium erythraeum IMS101 growth and photo-physiology to iron, CO2, and light intensity","volume":"9","author":"Boatman","year":"2018","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref26","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00227-008-0933-z","article-title":"Flux capacities and acclimation costs in Trichodesmium from the Gulf of Mexico","volume":"154","author":"Brown","year":"2008","journal-title":"Mar Biol"},{"key":"2024061320501716000_ref27","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/ngeo1181","article-title":"Dust-and mineral-iron utilization by the marine dinitrogen-fixer Trichodesmium","volume":"4","author":"Rubin","year":"2011","journal-title":"Nat Geosci"},{"key":"2024061320501716000_ref28","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1038\/ismej.2012.13","article-title":"Molecular evidence of iron limitation and availability in the global diazotroph Trichodesmium","volume":"6","author":"Chappell","year":"2012","journal-title":"ISME J"},{"key":"2024061320501716000_ref29","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/1758-2229.12308","article-title":"Phosphite utilization by the globally important marine diazotroph Trichodesmium","volume":"7","author":"Polyviou","year":"2015","journal-title":"Environ Microbiol Rep"},{"key":"2024061320501716000_ref30","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1111\/1462-2920.12424","article-title":"Trichodesmium\u2019s strategies to alleviate phosphorus limitation in the future acidified oceans","volume":"16","author":"Spungin","year":"2014","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref31","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.4319\/lo.2007.52.5.2221","article-title":"Molecular assessment of phosphorus and iron physiology in Trichodesmium populations from the western central and western South Atlantic","volume":"52","author":"Webb","year":"2007","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref32","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.4319\/lo.2001.46.6.1249","article-title":"Iron availability, cellular iron quotas, and nitrogen fixation in Trichodesmium","volume":"46","author":"Berman-Frank","year":"2001","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref33","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1111\/j.1462-2920.2007.01406.x","article-title":"Effects of iron limitation on the expression of metabolic genes in the marine cyanobacterium Trichodesmium erythraeum IMS101","volume":"9","author":"Shi","year":"2007","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2012.00043","article-title":"Iron utilization in marine cyanobacteria and eukaryotic algae","volume":"3","author":"Morrissey","year":"2012","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref35","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1039\/C4MT00026A","article-title":"Uptake mechanisms for inorganic iron and ferric citrate in Trichodesmium erythraeum IMS101","volume":"6","author":"Roe","year":"2014","journal-title":"Metallomics"},{"key":"2024061320501716000_ref36","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1469-8137.2008.02497.x","article-title":"Iron limitation in the marine cyanobacterium Trichodesmium reveals new insights into regulation of photosynthesis and nitrogen fixation","volume":"179","author":"K\u00fcpper","year":"2008","journal-title":"New Phytol"},{"key":"2024061320501716000_ref37","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.tim.2023.05.001","article-title":"Better together? Lessons on sociality from Trichodesmium","volume":"31","author":"Eichner","year":"2023","journal-title":"Trends Microbiol"},{"key":"2024061320501716000_ref38","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1038\/ismej.2017.74","article-title":"Epibionts dominate metabolic functional potential of Trichodesmium colonies from the oligotrophic ocean","volume":"11","author":"Frischkorn","year":"2017","journal-title":"ISME J"},{"key":"2024061320501716000_ref39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3354\/ame01571","article-title":"Characterization of bacterial epibionts on the cyanobacterium Trichodesmium","volume":"67","author":"Hmelo","year":"2012","journal-title":"Aquat Microb Ecol"},{"key":"2024061320501716000_ref40","doi-asserted-by":"crossref","first-page":"5151","DOI":"10.1111\/1462-2920.13513","article-title":"Microbial diversity within the Trichodesmium holobiont","volume":"18","author":"Rouco","year":"2016","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref41","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.4319\/lo.2013.58.5.1667","article-title":"Increased intracellular concentrations of DMSP and DMSO in iron-limited oceanic phytoplankton Thalassiosira oceanica and Trichodesmium erythraeum","volume":"58","author":"Bucciarelli","year":"2013","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref42","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/jpy.12117","article-title":"Cellular interactions: lessons from the nitrogen-fixing cyanobacteria","volume":"49","author":"Thompson","year":"2013","journal-title":"J Phycol"},{"key":"2024061320501716000_ref43","doi-asserted-by":"crossref","first-page":"9938","DOI":"10.1073\/pnas.1501615112","article-title":"Phytoplankton-bacterial interactions mediate micronutrient colimitation at the coastal Antarctic Sea ice edge","volume":"112","author":"Bertrand","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"key":"2024061320501716000_ref44","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.4319\/lo.2006.51.4.1762","article-title":"Nitrogen fixation and release of fixed nitrogen by Trichodesmium spp. in the Gulf of Mexico","volume":"51","author":"Mulholland","year":"2006","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2012.00375","article-title":"Influence of vitamin B auxotrophy on nitrogen metabolism in eukaryotic phytoplankton","volume":"3","author":"Bertrand","year":"2012","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref46","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.4319\/lo.2009.54.5.1438","article-title":"Cross-basin comparison of phosphorus stress and nitrogen fixation in Trichodesmium","volume":"54","author":"Hynes","year":"2009","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref47","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/ismej.2011.115","article-title":"Quorum sensing control of phosphorus acquisition in Trichodesmium consortia","volume":"6","author":"Van Mooy","year":"2012","journal-title":"ISME J"},{"key":"2024061320501716000_ref48","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/s42003-019-0534-z","article-title":"Colonies of marine cyanobacteria Trichodesmium interact with associated bacteria to acquire iron from dust","volume":"2","author":"Basu","year":"2019","journal-title":"Commun Biol"},{"key":"2024061320501716000_ref49","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.3389\/fmicb.2017.02683","article-title":"Desert dust as a source of iron to the globally important diazotroph Trichodesmium","volume":"8","author":"Polyviou","year":"2018","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref50","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1462-2920.2009.02026.x","article-title":"A molecular assessment of the iron stress response in the two phylogenetic clades of Trichodesmium","volume":"12","author":"Chappell","year":"2010","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref51","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.1111\/j.1462-2920.2011.02572.x","article-title":"The role of reduction in iron uptake processes in a unicellular, planktonic cyanobacterium","volume":"13","author":"Kranzler","year":"2011","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref52","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3390\/md17050281","article-title":"Cyanobacterial siderophores-physiology, structure, biosynthesis, and applications","volume":"17","author":"\u00c5rst\u00f8l","year":"2019","journal-title":"Mar Drugs"},{"key":"2024061320501716000_ref53","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1111\/j.1462-2920.2011.02653.x","article-title":"Acquisition of iron by Trichodesmium and associated bacteria in culture","volume":"14","author":"Roe","year":"2012","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref54","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.4319\/lo.2005.50.6.1918","article-title":"Structure of synechobactins, new siderophores of the marine cyanobacterium Synechococcus sp. PCC 7002","volume":"50","author":"Ito","year":"2005","journal-title":"Limnol Oceanogr"},{"key":"2024061320501716000_ref55","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1128\/JB.188.9.3182-3191.2006","article-title":"Regulatory roles for IscA and SufA in iron homeostasis and redox stress responses in the cyanobacterium Synechococcus sp. strain PCC 7002","volume":"188","author":"Balasubramanian","year":"2006","journal-title":"J Bacteriol"},{"key":"2024061320501716000_ref56","doi-asserted-by":"crossref","DOI":"10.1128\/aem.01732-22","article-title":"Diversity and evolution of iron uptake pathways in marine cyanobacteria from the perspective of the coastal strain Synechococcus sp. strain PCC 7002","volume":"89","author":"Yong","year":"2023","journal-title":"Appl Environ Microbiol"},{"key":"2024061320501716000_ref57","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/1462-2920.15324","article-title":"A unique porin meditates iron-selective transport through cyanobacterial outer membranes","volume":"23","author":"Qiu","year":"2021","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref58","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1111\/1462-2920.15347","article-title":"Artificial construction of the biocoenosis of deep-sea ecosystem via seeping methane","volume":"23","author":"Sun","year":"2021","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref59","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat Methods"},{"key":"2024061320501716000_ref60","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"2024061320501716000_ref61","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","article-title":"Differential expression analysis for sequence count data","volume":"11","author":"Anders","year":"2010","journal-title":"Genome Biol"},{"key":"2024061320501716000_ref62","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"key":"2024061320501716000_ref63","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1038\/s41396-022-01215-w","article-title":"Siderophores as an iron source for picocyanobacteria in deep chlorophyll maximum layers of the oligotrophic ocean","volume":"16","author":"Hogle","year":"2022","journal-title":"ISME J."},{"key":"2024061320501716000_ref64","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/ismej.2014.123","article-title":"New insights into iron acquisition by cyanobacteria: an essential role for ExbB-ExbD complex in inorganic iron uptake","volume":"9","author":"Jiang","year":"2015","journal-title":"ISME J"},{"key":"2024061320501716000_ref65","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nrmicro1464","article-title":"Multidrug-resistance efflux pumps-not just for resistance","volume":"4","author":"Piddock","year":"2006","journal-title":"Nat Rev Microbiol."},{"key":"2024061320501716000_ref66","doi-asserted-by":"crossref","first-page":"5370","DOI":"10.1128\/JB.00615-13","article-title":"The sll1951 gene encodes the surface layer protein of Synechocystis sp. strain PCC 6803","volume":"195","author":"Trautner","year":"2013","journal-title":"J Bacteriol"},{"key":"2024061320501716000_ref67","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.bbamem.2018.04.006","article-title":"The S-layer biogenesis system of Synechocystis 6803: role of Sll1180 and Sll1181 (E. Coli HlyB and HlyD analogs) as type-I secretion components for Sll1951 export","volume":"1860","author":"Agarwal","year":"2018","journal-title":"Biochim Biophys Acta Biomembr"},{"key":"2024061320501716000_ref68","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.1111\/1462-2920.14095","article-title":"Identification of inner membrane translocase components of TolC-mediated secretion in the cyanobacterium Synechocystis sp. PCC 6803","volume":"20","author":"Gon\u00e7alves","year":"2018","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref69","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.566691","article-title":"Iron uptake mechanisms in marine phytoplankton","volume":"11","author":"Sutak","year":"2020","journal-title":"Front Microbiol"},{"key":"2024061320501716000_ref70","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.5194\/bg-15-2565-2018","article-title":"N2 fixation as a dominant new N source in the western tropical South Pacific Ocean (OUTPACE cruise)","volume":"15","author":"Caffin","year":"2018","journal-title":"Biogeosciences"},{"key":"2024061320501716000_ref71","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.tim.2010.12.004","article-title":"Nitrogen fixation by marine cyanobacteria","volume":"19","author":"Zehr","year":"2011","journal-title":"Trends Microbiol"},{"key":"2024061320501716000_ref72","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/s41564-021-01028-1","article-title":"Dynamic diel proteome and daytime nitrogenase activity supports buoyancy in the cyanobacterium Trichodesmium","volume":"7","author":"Held","year":"2022","journal-title":"Nat Microbiol"},{"key":"2024061320501716000_ref73","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/1462-2920.15307","article-title":"Spatial and temporal variations in Synechococcus microdiversity in the Southern California coastal ecosystem","volume":"23","author":"Nagarkar","year":"2021","journal-title":"Environ Microbiol"},{"key":"2024061320501716000_ref74","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.04000-22","article-title":"Coexistence of dominant marine phytoplankton sustained by nutrient specialization","volume":"11","author":"Masuda","year":"2023","journal-title":"Microbiol Spectr"},{"key":"2024061320501716000_ref75","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1038\/ismej.2014.69","article-title":"Inference of interactions in cyanobacterial\u2013heterotrophic co-cultures via transcriptome sequencing","volume":"8","author":"Beliaev","year":"2014","journal-title":"ISME J."},{"key":"2024061320501716000_ref76","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10534-011-9495-5","article-title":"Siderophore-mediated iron uptake in two clades of Marinobacter spp. associated with phytoplankton: the role of light","volume":"25","author":"Amin","year":"2012","journal-title":"Biometals"},{"key":"2024061320501716000_ref77","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.1021\/acs.est.6b05833","article-title":"Iron ssotope fractionation during Fe(II) oxidation mediated by the oxygen-producing marine cyanobacterium Synechococcus PCC 7002","volume":"51","author":"Swanner","year":"2017","journal-title":"Environ Sci Technol"},{"key":"2024061320501716000_ref78","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s10534-009-9237-0","article-title":"Siderophores of Marinobacter aquaeolei: petrobactin and its sulfonated derivatives","volume":"22","author":"Homann","year":"2009","journal-title":"Biometals"},{"key":"2024061320501716000_ref79","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0055564","article-title":"Multidisciplinary evidences that Synechocystis PCC6803 exopolysaccharides operate in cell sedimentation and protection against salt and metal stresses","volume":"8","author":"Jittawuttipoka","year":"2013","journal-title":"PLoS One"}],"container-title":["ISME Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ismecommun\/advance-article-pdf\/doi\/10.1093\/ismeco\/ycae072\/57906569\/ycae072.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ismecommun\/article-pdf\/4\/1\/ycae072\/58214705\/ycae072.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ismecommun\/article-pdf\/4\/1\/ycae072\/58214705\/ycae072.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T07:50:25Z","timestamp":1718351425000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ismecommun\/article\/doi\/10.1093\/ismeco\/ycae072\/7682153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":79,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1,8]]}},"URL":"https:\/\/doi.org\/10.1093\/ismeco\/ycae072","relation":{},"ISSN":["2730-6151"],"issn-type":[{"value":"2730-6151","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1]]},"published":{"date-parts":[[2024,1]]},"article-number":"ycae072"}}