{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:18:48Z","timestamp":1788481128625,"version":"build-2803163510"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006727","name":"Hochschuljubil\u00e4umsfonds der Stadt Wien","doi-asserted-by":"publisher","award":["H-458732\/2023"],"award-info":[{"award-number":["H-458732\/2023"]}],"id":[{"id":"10.13039\/501100006727","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Union\u2019s Horizon 2020","award":["874735"],"award-info":[{"award-number":["874735"]}]},{"name":"FWF project","award":["10.55776\/P37311"],"award-info":[{"award-number":["10.55776\/P37311"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To assess the prevalence of ESBL Enterobacteriaceae among dogs attending a veterinary clinic in Vienna, characterize the isolates in terms of antimicrobial resistance, virulence and phylogenetic relationships.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Faecal samples of 88 dogs were streaked on selective plates, species were identified by MALDI-ToF MS, tested for resistance by a combination disk test and VITEK 2\u00ae, whole genome-sequenced, bioinformatically genotyped, phylogenetically analysed and screened for resistance and virulence genes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>ESBL Escherichia coli carriage rate was 14.8% (95% CI: [8.1\u201323.9]). No carbapenem resistance was found, but 53.8% of the isolates were classified genotypically as multi-drug resistant. Phylogenetic analyses revealed that half of the isolates belonged to animal and environment-associated phylogroups, while another half was human-associated, and included high-risk international clones of ST38, ST131 and ST141, which clustered primarily with human isolates. All isolates harboured various virulence-associated genes, including four isolates that encoded exotoxins, of which two were from the pandemic ST131 and emerging ST141 lineages.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Dogs in Vienna carry ESBL E. coli with high rates of multi-drug resistance and virulence, and a highly diverse population structure that includes pandemic human-associated lineages.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jac\/dkaf103","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T04:20:18Z","timestamp":1742358018000},"page":"1573-1576","source":"Crossref","is-referenced-by-count":3,"title":["Pandemic human-associated extended-spectrum \u03b2-lactamase-producing <i>Escherichia coli<\/i> lineages of ST38, ST131 and ST141 identified in Viennese dogs"],"prefix":"10.1093","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3122-3367","authenticated-orcid":false,"given":"Pia","family":"Saria","sequence":"first","affiliation":[{"name":"Centre for Food Science and Veterinary Public Health, Clinical Department for Farm Animals and Food Systems Science, University of Veterinary Medicine , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavlos G","family":"Doulidis","sequence":"additional","affiliation":[{"name":"Division for Small Animal Internal Medicine, Clinical Centre for Small Animals, Department for Small Animals and Horses, University of Veterinary Medicine , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Desvars-Larrive","sequence":"additional","affiliation":[{"name":"Centre for Food Science and Veterinary Public Health, Clinical Department for Farm Animals and Food Systems Science, University of Veterinary Medicine , Vienna ,","place":["Austria"]},{"name":"Complexity Science Hub Vienna , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienn Gr\u00e9ta","family":"T\u00f3th","sequence":"additional","affiliation":[{"name":"Centre for Bioinformatics, University of Veterinary Medicine , Budapest ,","place":["Hungary"]},{"name":"Department of Animal Breeding and Genetics, University of Veterinary Medicine , Budapest ,","place":["Hungary"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwan A","family":"Burgener","sequence":"additional","affiliation":[{"name":"Division for Small Animal Internal Medicine, Clinical Centre for Small Animals, Department for Small Animals and Horses, University of Veterinary Medicine , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandro","family":"Rodr\u00edguez-Rojas","sequence":"additional","affiliation":[{"name":"Division for Small 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