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The diarrhoea-type enterotoxins and vomiting-type enterotoxins it produces can lead to local or systemic infections. In recent years, resistance in B. cereus has been increasing, and multidrug-resistant bacteria have emerged. Therefore, understanding the drug resistance mechanism of B. cereus has become a matter of considerable concern in scientific research. In addition, this review explores the main resistance mechanisms of B. cereus to antibacterial drugs and discusses the detection and control strategies for the drug resistance of this bacterium. In addition, the purpose of this article is to deeply explore the drug resistance mechanism of B. cereus, with the aim of providing scientific basis and practical guidance for rational clinical drug use. Meanwhile, this article also provides innovative ideas for exploring new research approaches and screening safe and efficient antibacterial candidate drugs, with the aim of providing practical assistance for improving the current clinical cure rate.<\/jats:p>","DOI":"10.1093\/jac\/dkaf399","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T11:59:35Z","timestamp":1760183975000},"source":"Crossref","is-referenced-by-count":2,"title":["Progress in the study of drug resistance mechanism of\n                    <i>Bacillus cereus<\/i>"],"prefix":"10.1093","volume":"81","author":[{"given":"Yuhang","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology, Inner Mongolia Minzu University , Tongliao, Inner Mongolia 028300 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Inner Mongolia Minzu University , Tongliao, Inner Mongolia 028300 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhe","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Animal Disease Prevention and Control, Tongliao Naiman Banner Animal Disease Control and Prevention Center , Tongliao, Inner Mongolia 028300 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Animal Disease Prevention and Control, Tongliao Animal Disease Prevention and Control Center , Tongliao, Inner Mongolia 028000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhilin","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Inner Mongolia Minzu University , Tongliao, Inner Mongolia 028300 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