{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T13:42:41Z","timestamp":1780148561758,"version":"3.54.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,2,1]]},"DOI":"10.1093\/jac\/dki454","type":"journal-article","created":{"date-parts":[[2005,12,21]],"date-time":"2005-12-21T01:58:17Z","timestamp":1135130297000},"page":"349-352","source":"Crossref","is-referenced-by-count":35,"title":["Enhanced efficacy of pH-sensitive nystatin liposomes against Cryptococcus neoformans in murine model"],"prefix":"10.1093","volume":"57","author":[{"given":"Tahseen H.","family":"Nasti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masood A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Owais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,12,20]]},"reference":[{"key":"key\n\t\t\t\t20171010190540_B1","doi-asserted-by":"crossref","unstructured":"Diamond RD. The growing problem of mycoses in patients infected with the human immunodeficiency virus. Rev Infect Dis1991; 13: 480\u20136.","DOI":"10.1093\/clinids\/13.3.480"},{"key":"key\n\t\t\t\t20171010190540_B2","doi-asserted-by":"crossref","unstructured":"Anaissie E. Opportunistic mycoses in the immunocompromised host: experience at a cancer center and review. Clin Infect Dis1992; 14: S43\u201351.","DOI":"10.1093\/clinids\/14.Supplement_1.S43"},{"key":"key\n\t\t\t\t20171010190540_B3","doi-asserted-by":"crossref","unstructured":"Rude TH, Toffaletti DL, Cox GM et al. Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. Infect Immun2002; 70: 5684\u201394.","DOI":"10.1128\/IAI.70.10.5684-5694.2002"},{"key":"key\n\t\t\t\t20171010190540_B4","doi-asserted-by":"crossref","unstructured":"Chretien F, Lortholary O, Kansau I et al. Pathogenesis of cerebral Cryptococcus neoformans infection after fungemia. J Infect Dis2002; 186: 522\u201330.","DOI":"10.1086\/341564"},{"key":"key\n\t\t\t\t20171010190540_B5","doi-asserted-by":"crossref","unstructured":"Denning DW. Therapeutic outcome of invasive aspergillosis. Clin Infect Dis1996; 12: 1147\u2013201.","DOI":"10.1093\/clinids\/12.6.1147"},{"key":"key\n\t\t\t\t20171010190540_B6","doi-asserted-by":"crossref","unstructured":"Dupont B. Overview of lipid formulations of amphotericin B. J Antimicrob Chemother2002; 49 Suppl 1: 31\u20136.","DOI":"10.1093\/jac\/49.suppl_1.31"},{"key":"key\n\t\t\t\t20171010190540_B7","doi-asserted-by":"crossref","unstructured":"Straubinger RM. pH-sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells. Methods Enzymol1993; 221: 361\u201376.","DOI":"10.1016\/0076-6879(93)21030-C"},{"key":"key\n\t\t\t\t20171010190540_B8","doi-asserted-by":"crossref","unstructured":"Hope MJ, Mui B, Ansell S et al. Cationic lipids, phosphatidylethanolamine and the intracellular delivery of polymeric, nucleic acid based drugs. Mol Membr Biol1998; 15: 1\u201314.","DOI":"10.3109\/09687689809027512"},{"key":"key\n\t\t\t\t20171010190540_B9","doi-asserted-by":"crossref","unstructured":"Singleton WS, Gray MS, Brown ML. A method for adsorbent fractionation of cottonseed oil for experimental intravenous fat emulsions. J Am Oil Chem Soc1965; 42: 53\u20136.","DOI":"10.1007\/BF02558256"},{"key":"key\n\t\t\t\t20171010190540_B10","doi-asserted-by":"crossref","unstructured":"Owais M, Gupta CM. Liposome mediated cytosolic delivery of macromolecules and its possible use in vaccine development. Eur J Biochem2000; 267: 3946\u201356.","DOI":"10.1046\/j.1432-1327.2000.01447.x"},{"key":"key\n\t\t\t\t20171010190540_B11","doi-asserted-by":"crossref","unstructured":"Mehta TR, Hopfer RL, McQueen T et al. Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections. Antimicrob Agents Chemother1987; 31: 1901\u20133.","DOI":"10.1128\/AAC.31.12.1901"},{"key":"key\n\t\t\t\t20171010190540_B12","unstructured":"National Committee for Clinical Laboratory Standards. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts: Approved Standard M27-A. NCCLS, Villanova, PA, USA, 1997."},{"key":"key\n\t\t\t\t20171010190540_B13","doi-asserted-by":"crossref","unstructured":"Khan MA, Syed FM, Nasti HT et al. Use of tuftsin bearing nystatin liposomes against an isolate of Candida albicans showing less in vivo susceptibility to amphotericin B. J Drug Target2003; 11: 93\u20139.","DOI":"10.1080\/1061186031000119093"},{"key":"key\n\t\t\t\t20171010190540_B14","doi-asserted-by":"crossref","unstructured":"Lutwyche P, Cordeiro C, Wiseman DJ et al. Intracellular delivery and antibacterial activity of gentamicin encapsulated in pH-sensitive liposomes. Antimicrob Agents Chemother1998; 42: 2511\u201320.","DOI":"10.1128\/AAC.42.10.2511"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/57\/2\/349\/2407943\/dki454.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T18:00:53Z","timestamp":1555005653000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/jac\/article\/57\/2\/349\/804721\/Enhanced-efficacy-of-pHsensitive-nystatin"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,20]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,12,20]]},"published-print":{"date-parts":[[2006,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dki454","relation":{},"ISSN":["1460-2091","0305-7453"],"issn-type":[{"value":"1460-2091","type":"electronic"},{"value":"0305-7453","type":"print"}],"subject":[],"published-other":{"date-parts":[[2006,2]]},"published":{"date-parts":[[2005,12,20]]}}}