{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T05:43:49Z","timestamp":1781502229704,"version":"3.54.1"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Antimicrobial Chemotherapy"],"DOI":"10.1093\/jac\/dkn392","type":"journal-article","created":{"date-parts":[[2008,9,18]],"date-time":"2008-09-18T14:37:10Z","timestamp":1221748630000},"page":"1234-1240","source":"Crossref","is-referenced-by-count":27,"title":["Breakthrough in penicillin resistance? Streptococcus pneumoniae isolates with penicillin\/cefotaxime MICs of 16 mg\/L and their genotypic and geographical relatedness"],"prefix":"10.1093","volume":"62","author":[{"given":"F.","family":"Soriano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Cafini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Tarrago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Alou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-J.","family":"Gimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Gracia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-C.","family":"Ponte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Leu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Letowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Fenoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,9,10]]},"reference":[{"issue":"12","key":"1_21234260","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.3201\/eid1110.051014","volume":"11","author":"Courvalin","year":"2005","journal-title":"Emerging infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1080-6040","issn-type":"print"},{"key":"2_28005844","doi-asserted-by":"crossref","first-page":"S363","DOI":"10.1086\/382696","volume":"38","year":"2004","journal-title":"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"issue":"3","key":"3_14475893","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/j.1365-2958.1993.tb01723.x","volume":"9","author":"Dowson","year":"1993","journal-title":"Molecular microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0950-382X","issn-type":"print"},{"issue":"8","key":"4_9691060","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1111\/j.1365-2958.1991.tb00821.x","volume":"5","author":"Laible","year":"1991","journal-title":"Molecular microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0950-382X","issn-type":"print"},{"issue":"9","key":"5_18300089","doi-asserted-by":"publisher","first-page":"3563","DOI":"10.1128\/AAC.48.9.3563-3566.2004","volume":"48","author":"Hauser","year":"2004","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"8","key":"6_17149736","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1128\/AAC.46.8.2349-2357.2002","volume":"46","author":"du Plessis","year":"2002","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"2","key":"7_21250509","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1093\/jac\/dki442","volume":"57","year":"2006","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"5","key":"8_21746254","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1093\/jac\/dkl083","volume":"57","year":"2006","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"7","key":"9_11212512","doi-asserted-by":"publisher","first-page":"2565","DOI":"10.1128\/JCM.39.7.2565-2571.2001","volume":"39","author":"McGee","year":"2001","journal-title":"Journal of Clinical Microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"issue":"26","key":"10_10598326","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1056\/NEJM200012283432603","volume":"343","author":"Whitney","year":"2000","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"8","key":"11_18271466","doi-asserted-by":"publisher","first-page":"3016","DOI":"10.1128\/AAC.48.8.3016-3023.2004","volume":"48","author":"Schrag","year":"2004","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"4","key":"12_10646600","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/S1201-9712(00)90112-7","volume":"4","author":"Huebner RE","year":"2000","journal-title":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1201-9712","issn-type":"print"},{"issue":"5","key":"13_18827444","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1128\/AAC.49.5.1965-1972.2005","volume":"49","author":"Perez-Trallero","year":"2005","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"12","key":"14_11401604","doi-asserted-by":"publisher","first-page":"3334","DOI":"10.1128\/AAC.45.12.3334-3340.2001","volume":"45","author":"Perez-Trallero","year":"2001","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"key":"15_31929855","first-page":"437","volume":"340","year":"1992","ISSN":"https:\/\/id.crossref.org\/issn\/1474-547X","issn-type":"print"},{"issue":"1","key":"16_10721801","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00006454-199901000-00002","volume":"18","author":"Dowell","year":"1999","journal-title":"The Pediatric infectious disease journal","ISSN":"https:\/\/id.crossref.org\/issn\/0891-3668","issn-type":"print"},{"issue":"5","key":"17_17189233","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1086\/341978","volume":"35","author":"Lonks","year":"2002","journal-title":"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"issue":"8","key":"18_15954243","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1056\/NEJM199508243330802","volume":"333","author":"Pallares","year":"1995","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"3","key":"21_16696399","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1128\/JCM.35.3.764-766.1997","volume":"35","author":"Fenoll","year":"1997","journal-title":"Journal of Clinical Microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"issue":"11","key":"22_6255733","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1099\/00221287-144-11-3049","volume":"144","year":"1998","journal-title":"Microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/1350-0872","issn-type":"print"},{"issue":"1","key":"24_10267063","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/infdis\/168.1.158","volume":"168","author":"Soares","year":"1993","journal-title":"The Journal of infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"issue":"9","key":"25_16037533","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/JCM.33.9.2233-2239.1995","volume":"33","author":"Tenover","year":"1995","journal-title":"Journal of Clinical Microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"issue":"2","key":"26_9521117","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1093\/infdis\/164.2.302","volume":"164","author":"Mu\u00a0\u00a0oz","year":"1991","journal-title":"The Journal of infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"issue":"1","key":"27_5243695","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1365-2958.1989.tb00108.x","volume":"3","author":"Dowson","year":"1989","journal-title":"Molecular microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0950-382X","issn-type":"print"},{"issue":"9","key":"28_9691089","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1111\/j.1365-2958.1991.tb02155.x","volume":"5","author":"Coffey","year":"1991","journal-title":"Molecular microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/0950-382X","issn-type":"print"},{"issue":"23","key":"29_10548053","doi-asserted-by":"publisher","first-page":"6798","DOI":"10.1128\/JB.182.23.6798-6805.2000","volume":"182","author":"Filipe","year":"2000","journal-title":"Journal of Bacteriology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9193","issn-type":"print"},{"issue":"5","key":"32_17011481","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1128\/AAC.46.5.1273-1280.2002","volume":"46","author":"Nagai","year":"2002","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"4","key":"33_16260171","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1128\/AAC.40.4.829","volume":"40","author":"Grebe","year":"1996","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"10","key":"36_6182139","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1128\/AAC.42.10.2768","volume":"42","author":"Ruiz","year":"1998","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"2","key":"37_10474004","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1089\/107662900419401","volume":"6","author":"Smith","year":"2000","journal-title":"Microbial drug resistance (Larchmont, N.Y.)","ISSN":"https:\/\/id.crossref.org\/issn\/1076-6294","issn-type":"print"},{"issue":"3","key":"38_6515737","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1086\/315316","volume":"181","author":"Porat","year":"2000","journal-title":"The Journal of infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"issue":"1","key":"39_6113490","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/jac\/42.1.115","volume":"42","author":"Johnson","year":"1998","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/62\/6\/1234\/2307361\/dkn392.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T09:59:16Z","timestamp":1588931956000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article-lookup\/doi\/10.1093\/jac\/dkn392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,10]]},"references-count":32,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2008,9,10]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkn392","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,10]]}}}