{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:16:39Z","timestamp":1790788599388,"version":"4.1.0"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"Supplement 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Antimicrobial Chemotherapy"],"published-print":{"date-parts":[[2011,4,1]]},"DOI":"10.1093\/jac\/dkq516","type":"journal-article","created":{"date-parts":[[2011,3,11]],"date-time":"2011-03-11T05:48:21Z","timestamp":1299822501000},"page":"ii25-ii31","source":"Crossref","is-referenced-by-count":79,"title":["Antibiotic dosing in critical illness"],"prefix":"10.1093","volume":"66","author":[{"given":"C.","family":"McKenzie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,3,11]]},"reference":[{"issue":"1","key":"1_30133937","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/01.CCM.0000298158.12101.41","volume":"36","author":"Dellinger","year":"2008","journal-title":"Critical care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0090-3493","issn-type":"print"},{"issue":"19","key":"2_11371796","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1056\/NEJMoa010307","volume":"345","author":"Rivers","year":"2001","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"13","key":"3_34382069","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1056\/NEJMoa0810625","volume":"360","year":"2009","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"7464","key":"4_18302226","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1136\/bmj.38181.482222.55","volume":"329","year":"2004","journal-title":"BMJ","ISSN":"https:\/\/id.crossref.org\/issn\/0959-8138","issn-type":"print"},{"issue":"10","key":"5_11048671","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1056\/NEJM200103083441001","volume":"344","author":"Bernard","year":"2001","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"6","key":"6_22192883","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1097\/01.CCM.0000217961.75225.E9","volume":"34","author":"Kumar","year":"2006","journal-title":"Critical care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0090-3493","issn-type":"print"},{"issue":"1","key":"8_17990645","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s00134-003-2059-6","volume":"30","author":"Erstad","year":"2004","journal-title":"Intensive care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0342-4642","issn-type":"print"},{"issue":"3","key":"9_36510914","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1086\/650446","volume":"31","author":"Christoff","year":"2010","journal-title":"Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America","ISSN":"https:\/\/id.crossref.org\/issn\/0899-823X","issn-type":"print"},{"issue":"1","key":"10_38733378","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1093\/infdis\/155.1.93","volume":"155","year":"1987","journal-title":"Journal of Infectious Diseases","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"key":"12_39423096","first-page":"P61","volume":"13","year":"2009","journal-title":"Critical care (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/1364-8535","issn-type":"print"},{"issue":"3","key":"13_10706336","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1056\/NEJM199901213400307","volume":"340","author":"Wheeler","year":"1999","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"9453","key":"14_18655572","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0140-6736(04)17667-8","volume":"365","author":"Annane","year":"2005","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"2","key":"15_14464835","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2165\/00003088-199325020-00003","volume":"25","author":"Cheymol","year":"1993","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"2","key":"16_36474722","doi-asserted-by":"publisher","first-page":"71","DOI":"10.2165\/11318100-000000000-00000","volume":"49","author":"Hanley","year":"2010","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"2","key":"17_19325778","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1378\/chest.128.2.545","volume":"128","author":"Panidis","year":"2005","journal-title":"Chest","ISSN":"https:\/\/id.crossref.org\/issn\/0012-3692","issn-type":"print"},{"issue":"8849","key":"18_10191645","first-page":"895","volume":"341","author":"Reeves","year":"1993","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"7","key":"19_17150353","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1007\/s00134-002-1313-7","volume":"28","author":"Buijk","year":"2002","journal-title":"Intensive care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0342-4642","issn-type":"print"},{"issue":"1","key":"21_15655545","doi-asserted-by":"publisher","first-page":"32","DOI":"10.2165\/00003088-199427010-00004","volume":"27","author":"Barclay","year":"1994","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"11","key":"22_35413824","doi-asserted-by":"publisher","first-page":"4612","DOI":"10.1128\/AAC.00965-08","volume":"53","year":"2009","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"2","key":"23_15860989","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2165\/00003088-199528020-00005","volume":"28","author":"Hyatt","year":"1995","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"4","key":"24_6541544","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/S0924-8579(99)00114-4","volume":"13","author":"Li","year":"2000","journal-title":"International journal of antimicrobial agents","ISSN":"https:\/\/id.crossref.org\/issn\/0924-8579","issn-type":"print"},{"issue":"1","key":"25_10931171","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00003088-199937010-00001","volume":"37","author":"Li","year":"1999","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"6","key":"26_31857323","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.ijantimicag.2008.05.019","volume":"32","author":"Conil","year":"2008","journal-title":"International journal of antimicrobial agents","ISSN":"https:\/\/id.crossref.org\/issn\/0924-8579","issn-type":"print"},{"issue":"2","key":"27_22323589","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3121\/cmr.4.2.138","volume":"4","author":"Falagas","year":"2006","journal-title":"Clinical Medicine & Research","ISSN":"https:\/\/id.crossref.org\/issn\/1539-4182","issn-type":"print"},{"issue":"2","key":"28_21348122","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1093\/jac\/dki461","volume":"57","year":"2006","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"6","key":"29_11597568","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1059\/0003-4819-72-6-857","volume":"72","author":"KOCH-WESER","year":"1970","journal-title":"Annals of Internal Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"30_12211832","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.0954-6820.1965.tb01882.x","volume":"177","author":"Tallgren","year":"1965","journal-title":"Acta medica Scandinavica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-6101","issn-type":"print"},{"issue":"4","key":"31_31517743","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1097\/MCC.0b013e3283021b3a","volume":"14","author":"Roberts","year":"2008","journal-title":"Current opinion in critical care","ISSN":"https:\/\/id.crossref.org\/issn\/1070-5295","issn-type":"print"},{"key":"32_39423098","first-page":"1320","volume":"26","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/1875-9114","issn-type":"print"},{"issue":"5","key":"33_31009744","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1097\/CCM.0b013e3181704625","volume":"36","author":"Roberts","year":"2008","journal-title":"Critical care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0090-3493","issn-type":"print"},{"issue":"6","key":"34_11186024","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0924-8579(01)00329-6","volume":"17","author":"Nicolau","year":"2001","journal-title":"International journal of antimicrobial agents","ISSN":"https:\/\/id.crossref.org\/issn\/0924-8579","issn-type":"print"},{"issue":"2","key":"35_21540600","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1345\/aph.1G467","volume":"40","year":"2006","journal-title":"The Annals of Pharmacotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0012-6578","issn-type":"print"},{"issue":"1","key":"36_32992438","doi-asserted-by":"publisher","first-page":"82","DOI":"10.2146\/ajhp080434","volume":"66","author":"Rybak","year":"2009","journal-title":"American Journal of Health-System Pharmacy","ISSN":"https:\/\/id.crossref.org\/issn\/1079-2082","issn-type":"print"},{"issue":"8939-8940","key":"37_15699552","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1016\/S0140-6736(94)92890-8","volume":"344","author":"Saunders","year":"1994","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"9","key":"38_11277239","doi-asserted-by":"publisher","first-page":"2460","DOI":"10.1128\/AAC.45.9.2460-2467.2001","volume":"45","author":"Wysocki","year":"2001","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"9","key":"39_19414656","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1097\/01.CCM.0000178180.61305.1D","volume":"33","author":"Rello","year":"2005","journal-title":"Critical care medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0090-3493","issn-type":"print"},{"issue":"1","key":"41_16335828","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1093\/bja\/77.1.32","volume":"77","author":"Park","year":"1996","journal-title":"British Journal of Anaesthesia","ISSN":"https:\/\/id.crossref.org\/issn\/0007-0912","issn-type":"print"},{"issue":"6","key":"42_4966572","doi-asserted-by":"crossref","first-page":"347","DOI":"10.2165\/00003088-198814060-00003","volume":"14","author":"Bodenham","year":"1988","journal-title":"Clinical pharmacokinetics","ISSN":"https:\/\/id.crossref.org\/issn\/0312-5963","issn-type":"print"},{"issue":"6","key":"43_30125262","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1055\/s-2007-996406","volume":"28","author":"Rea","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1069-3424","issn-type":"print"},{"issue":"4","key":"44_17284284","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1053\/jarr.2002.35561","volume":"9","author":"Ronco","year":"2002","journal-title":"Advances in renal replacement therapy","ISSN":"https:\/\/id.crossref.org\/issn\/1073-4449","issn-type":"print"},{"key":"45_39423100","first-page":"524","volume":"54","year":"1991","journal-title":"British journal of hospital medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1064","issn-type":"print"},{"issue":"6","key":"46_32727555","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1097\/MCC.0b013e32830f937c","volume":"14","author":"Bouman","year":"2008","journal-title":"Current opinion in critical care","ISSN":"https:\/\/id.crossref.org\/issn\/1070-5295","issn-type":"print"},{"key":"49_39423101","doi-asserted-by":"crossref","first-page":"P451","DOI":"10.1186\/cc9303","volume":"14","year":"2010","journal-title":"Critical care (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/1364-8535","issn-type":"print"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/66\/suppl_2\/ii25\/2344189\/dkq516.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T11:18:31Z","timestamp":1503487111000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article-lookup\/doi\/10.1093\/jac\/dkq516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,11]]},"references-count":43,"journal-issue":{"issue":"Supplement 2","published-online":{"date-parts":[[2011,3,11]]},"published-print":{"date-parts":[[2011,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkq516","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,11]]}}}