{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:28:16Z","timestamp":1790044096736,"version":"4.0.1"},"reference-count":38,"publisher":"Oxford University Press (OUP)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1093\/jac\/dkx187","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T08:20:42Z","timestamp":1496132442000},"source":"Crossref","is-referenced-by-count":8,"title":["Imbalance in mitochondrial dynamics and apoptosis in pregnancies among HIV-infected women on HAART with obstetric complications"],"prefix":"10.1093","author":[{"given":"Mariona","family":"Guitart-Mampel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Sandra","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constanza","family":"Moren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Catalan-Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Tobias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Gonzalez-Casacuberta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana L.","family":"Juarez-Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M.","family":"Gatell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Cardellach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose C.","family":"Milisenda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M.","family":"Grau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gratacos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Garrabou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,7,4]]},"reference":[{"key":"key\n\t\t\t\t20170731062403_dkx187-B1","doi-asserted-by":"crossref","first-page":"766","DOI":"10.7326\/0003-4819-154-11-201106070-00345","article-title":"Thirty years of HIV and AIDS: future challenges and opportunities","volume":"154","year":"2011","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B2","doi-asserted-by":"crossref","first-page":"744","DOI":"10.2174\/138920012800840365","article-title":"Pharmacokinetic considerations of perinatal antiretroviral therapy","volume":"13","year":"2012","journal-title":"Curr Drug Metab"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B3","first-page":"CD003510.","article-title":"Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B4","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1086\/423176","article-title":"Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals","volume":"39","year":"2004","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B5","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1097\/INF.0000000000000894","article-title":"Decreased mitochondrial function among healthy infants exposed to antiretrovirals during gestation, delivery and the neonatal period","volume":"34","year":"2015","journal-title":"Pediatr Infect Dis J"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B6","doi-asserted-by":"crossref","first-page":"9897","DOI":"10.3390\/ijerph110909897","article-title":"Mitochondrial toxicity in human pregnancy: an update on clinical and experimental approaches in the last 10\u2009years","volume":"11","year":"2014","journal-title":"Int J Environ Res Public Health"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B7","first-page":"159","article-title":"Molecular basis of reduced birth weight in smoking pregnant women: mitochondrial dysfunction and apoptosis","volume":"21","year":"2014","journal-title":"Addict Biol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/00002030-200301240-00023","article-title":"Case report: nucleoside analogue-induced lactic acidosis in the third trimester of pregnancy","volume":"17","year":"2003","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B9","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1056\/NEJMoa991159","article-title":"Antiretroviral therapy during pregnancy and the risk of an adverse outcome","volume":"346","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B10","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1097\/00002030-200007070-00012","article-title":"Risk factors for preterm birth, low birth weight, and intrauterine growth retardation in infants born to HIV-infected pregnant women receiving zidovudine. Pediatric AIDS Clinical Trials Group 185 Team","volume":"14","year":"2000","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/01.aids.0000198090.70325.bd","article-title":"Increased risk of pre-eclampsia and fetal death in HIV-infected pregnant women receiving highly active antiretroviral therapy","volume":"20","year":"2006","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B12","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1097\/00002030-200411190-00019","article-title":"Increased risk of adverse pregnancy outcomes in HIV-infected women treated with highly active antiretroviral therapy in Europe","volume":"18","year":"2004","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B13","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1177\/135965350801300607","article-title":"Mitochondrial DNA depletion in oocytes of HIV-infected antiretroviral-treated infertile women","volume":"13","year":"2008","journal-title":"Antivir Ther"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B14","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/00002030-200404300-00009","article-title":"Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir","volume":"18","year":"2004","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B15","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nm0595-417","article-title":"Mitochondrial toxicity of antiviral drugs","volume":"1","year":"1995","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B16","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/QAI.0b013e3181bd564c","article-title":"Genetic and functional mitochondrial assessment of HIV-infected patients developing HAART-related hyperlactatemia","volume":"52","year":"2009","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B17","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3851\/IMP1764","article-title":"Decreased mitochondrial DNA content in subcutaneous fat from HIV-infected women taking antiretroviral therapy as measured at delivery","volume":"16","year":"2011","journal-title":"Antivir Ther"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B18","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1253\/circj.CJ-14-0240","article-title":"Regulation of mitochondrial dynamics and cell fate","volume":"78","year":"2014","journal-title":"Circ J"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B19","first-page":"109","article-title":"Metabolic stress and disorders related to alterations in mitochondrial fission or fusion","volume":"5","year":"2013","journal-title":"Mol Cell Pharmacol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B20","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1056\/NEJMra1215233","article-title":"Mitochondrial dynamics\u2014mitochondrial fission and fusion in human diseases","volume":"369","year":"2013","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B21","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1089\/ars.2010.3286","article-title":"Mitochondrial dynamics in diabetes","volume":"14","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B22","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1096\/fj.13-230037","article-title":"Role of mitofusin 2 (Mfn2) in controlling cellular proliferation","volume":"28","year":"2014","journal-title":"FASEB J"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B23","article-title":"Mechanisms of mitochondrial fission and fusion","volume":"5","year":"2013","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B24","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.bbamcr.2006.02.004","article-title":"Get the balance right: mitofusins roles in health and disease","volume":"1763","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B25","doi-asserted-by":"crossref","first-page":"e33657.","DOI":"10.1371\/journal.pone.0033657","article-title":"HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction","volume":"7","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B26","doi-asserted-by":"crossref","first-page":"e0125680.","DOI":"10.1371\/journal.pone.0125680","article-title":"Mfn2 affects embryo development via mitochondrial dysfunction and apoptosis","volume":"10","year":"2015","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B27","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/j.1468-1331.2012.03670.x","article-title":"Mitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer's disease","volume":"19","year":"2012","journal-title":"Eur J Neurol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B28","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/infdis\/jir764","article-title":"The effects of sepsis on mitochondria","volume":"205","year":"2012","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B29","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0006-291X(03)00631-4","article-title":"Mechanism of HIV-1 viral protein R-induced apoptosis","volume":"304","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B30","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1152\/physiolgenomics.00059.2014","article-title":"In utero exposure to prepregnancy maternal obesity and postweaning high-fat diet impair regulators of mitochondrial dynamics in rat placenta and offspring","volume":"46","year":"2014","journal-title":"Physiol Genomics"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B31","doi-asserted-by":"crossref","first-page":"e63206.","DOI":"10.1371\/journal.pone.0063206","article-title":"Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures","volume":"8","year":"2013","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B32","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1681\/ASN.2014010126","article-title":"Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia","volume":"26","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B33","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1067\/mob.2002.119176","article-title":"Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation","volume":"186","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B34","doi-asserted-by":"crossref","first-page":"e99000.","DOI":"10.1371\/journal.pone.0099000","article-title":"Limited evolution of inferred HIV-1 tropism while viremia is undetectable during standard HAART therapy","volume":"9","year":"2014","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B35","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/QAD.0b013e32834f3232","article-title":"Perinatal outcomes, mitochondrial toxicity and apoptosis in HIV-treated pregnant women and in-utero-exposed newborn","volume":"26","year":"2012","journal-title":"AIDS"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B36","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.canlet.2014.12.025","article-title":"Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells","volume":"358","year":"2015","journal-title":"Cancer Lett"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B37","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1073\/pnas.0703976104","article-title":"Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins","volume":"104","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170731062403_dkx187-B38","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/nature05111","article-title":"Role of Bax and Bak in mitochondrial morphogenesis","volume":"443","year":"2006","journal-title":"Nature"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/doi\/10.1093\/jac\/dkx187\/19376986\/dkx187.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T20:09:30Z","timestamp":1692821370000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article-lookup\/doi\/10.1093\/jac\/dkx187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,4]]},"references-count":38,"URL":"https:\/\/doi.org\/10.1093\/jac\/dkx187","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,4]]}}}