{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:19:54Z","timestamp":1790399994764,"version":"4.1.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"9","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5KL2 RR025766\/RR\/NCRR"],"award-info":[{"award-number":["5KL2 RR025766\/RR\/NCRR"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2 TR000118\/TR\/NCATS"],"award-info":[{"award-number":["KL2 TR000118\/TR\/NCATS"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,1]]},"DOI":"10.1093\/jac\/dkx200","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T15:10:38Z","timestamp":1496416238000},"page":"2461-2468","source":"Crossref","is-referenced-by-count":35,"title":["Emerging multidrug resistance in community-associated Staphylococcus aureus involved in skin and soft tissue infections and nasal colonization"],"prefix":"10.1093","volume":"72","author":[{"given":"Grace C.","family":"Lee","sequence":"first","affiliation":[{"name":"College of Pharmacy, The University of Texas at Austin, San Antonio, TX, USA"},{"name":"Pharmacotherapy Education and Research Center, School of Medicine, The University of Texas Health Science Center, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Dallas","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, School of Health Professions, University of Texas Health Science Center, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biology, The University of Texas San Antonio, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall J.","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Pathology and Genomic Medicine, Houston Methodist Hospital and Research Institute, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Lawson","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Texas at Austin, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Wilson","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Texas at Austin, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Frei","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Texas at Austin, San Antonio, TX, USA"},{"name":"Pharmacotherapy Education and Research Center, School of Medicine, The University of Texas Health Science Center, San Antonio, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,7,3]]},"reference":[{"key":"key\n\t\t\t\t20180313122435_dkx200-B1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nrmicro2200","article-title":"Waves of resistance: Staphylococcus aureus in the antibiotic era","volume":"7","author":"Chambers","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B2","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/S0140-6736(09)61999-1","article-title":"Community-associated meticillin-resistant Staphylococcus aureus","volume":"375","author":"DeLeo","year":"2010","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B3","doi-asserted-by":"crossref","first-page":"249","DOI":"10.7326\/0003-4819-148-4-200802190-00204","article-title":"Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men","volume":"148","author":"Diep","year":"2008","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B4","doi-asserted-by":"crossref","first-page":"6738","DOI":"10.1073\/pnas.1401006111","article-title":"Molecular tracing of the emergence, diversification, and transmission of S. aureus sequence type 8 in a New York community","volume":"111","author":"Uhlemann","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/cid\/ciq067","article-title":"Antimicrobial resistance: not community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)! A clinician's guide to community MRSA - its evolving antimicrobial resistance and implications for therapy","volume":"52","author":"Chua","year":"2011","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B6","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/cid\/ciu444","article-title":"Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America","volume":"59","author":"Stevens","year":"2014","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B7","doi-asserted-by":"crossref","first-page":"e1002824","DOI":"10.1371\/journal.ppat.1002824","article-title":"Routine use of microbial whole genome sequencing in diagnostic and public health microbiology","volume":"8","author":"Koser","year":"2012","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B8","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.tig.2014.07.003","article-title":"Whole-genome sequencing to control antimicrobial resistance","volume":"30","author":"Koser","year":"2014","journal-title":"Trends Genet"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B9","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1093\/jac\/dkt494","article-title":"Rapid single-colony whole-genome sequencing of bacterial pathogens","volume":"69","author":"Koser","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B10","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/jac\/dkt413","article-title":"Evolution of methicillin-resistant Staphylococcus aureus towards increasing resistance","volume":"69","author":"Strommenger","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B11","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1093\/gbe\/evu092","article-title":"Dissecting vancomycin-intermediate resistance in Staphylococcus aureus using genome-wide association","volume":"6","author":"Alam","year":"2014","journal-title":"Genome Biol Evol"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B12","doi-asserted-by":"crossref","first-page":"e1002359","DOI":"10.1371\/journal.ppat.1002359","article-title":"Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR","volume":"7","author":"Howden","year":"2011","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B13","doi-asserted-by":"crossref","first-page":"9451","DOI":"10.1073\/pnas.0609839104","article-title":"Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing","volume":"104","author":"Mwangi","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B14","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3122\/jabfm.2011.05.110073","article-title":"Prevalence, severity, and treatment of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections in 10 medical clinics in Texas: a South Texas Ambulatory Research Network (STARNet) study","volume":"24","author":"Forcade","year":"2011","journal-title":"J Am Board Fam Med"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B15","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1017\/S0950268816001709","article-title":"Predictors of community-associated Staphylococcus aureus, methicillin-resistant and methicillin-susceptible Staphylococcus aureus skin and soft tissue infections in primary-care settings","volume":"144","author":"Lee","year":"2016","journal-title":"Epidemiol Infect"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B16","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Fourth Informational Supplement M100-S24","author":"Clinical and Laboratory Standards Institute","year":"2014"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B17","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B18","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0140-6736(06)68231-7","article-title":"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus","volume":"367","author":"Diep","year":"2006","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B19","doi-asserted-by":"crossref","first-page":"e7767.","DOI":"10.1371\/journal.pone.0007767","article-title":"BFAST: an alignment tool for large scale genome resequencing","volume":"4","author":"Homer","year":"2009","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B20","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1086\/533502","article-title":"What is community-associated methicillin-resistant Staphylococcus aureus?","volume":"197","author":"David","year":"2008","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B21","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1128\/JCM.01057-13","article-title":"Asymptomatic carriage of sequence type 398, spa type t571 methicillin-susceptible Staphylococcus aureus in an urban jail: a newly emerging, transmissible pathogenic strain","volume":"51","author":"David","year":"2013","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B22","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1128\/AAC.02412-14","article-title":"In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing","volume":"58","author":"Carattoli","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B23","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1128\/AAC.01310-13","article-title":"ARG-ANNOT, a new bioinformatic tool to discover antibiotic resistance genes in bacterial genomes","volume":"58","author":"Gupta","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B24","doi-asserted-by":"crossref","first-page":"e01692","DOI":"10.1128\/mBio.01692-14","article-title":"Absence of patient-to-patient intrahospital transmission of Staphylococcus aureus as determined by whole-genome sequencing","volume":"5","author":"Long","year":"2014","journal-title":"MBio"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B25","doi-asserted-by":"crossref","first-page":"e1120","DOI":"10.1371\/journal.pone.0001120","article-title":"Molecular correlates of host specialization in Staphylococcus aureus","volume":"2","author":"Herron-Olson","year":"2007","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B26","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1001\/jama.298.15.1763","article-title":"Invasive methicillin-resistant Staphylococcus aureus infections in the United States","volume":"298","author":"Klevens","year":"2007","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B27","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1086\/587893","article-title":"A population-based study of the incidence and molecular epidemiology of methicillin-resistant Staphylococcus aureus disease in San Francisco, 2004-2005","volume":"46","author":"Liu","year":"2008","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B28","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1093\/jac\/dku174","article-title":"Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe","volume":"69","author":"Nurjadi","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B29","doi-asserted-by":"crossref","first-page":"567.e1","DOI":"10.1016\/j.cmi.2015.01.016","article-title":"Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant Staphylococcus aureus to Europe","volume":"21","author":"Nurjadi","year":"2015","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B30","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1128\/AAC.01128-08","article-title":"Identification of a novel trimethoprim resistance gene, dfrK, in a methicillin-resistant Staphylococcus aureus ST398 strain and its physical linkage to the tetracycline resistance gene tet(L)","volume":"53","author":"Kadlec","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B31","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3122\/jabfm.2013.05.120247","article-title":"Treatment failure and costs in patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections: a South Texas Ambulatory Research Network (STARNet) study","volume":"26","author":"Labreche","year":"2013","journal-title":"J Am Board Fam Med"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B32","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1056\/NEJMoa043252","article-title":"Methicillin-resistant Staphylococcus aureus disease in three communities","volume":"352","author":"Fridkin","year":"2005","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/cid\/civ794","article-title":"Genomic epidemiology of USA300 methicillin resistant Staphylococcus aureus in an urban community","volume":"62","author":"Popovich","year":"2016","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B34","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jhin.2011.04.028","article-title":"Community-associated meticillin-resistant Staphylococcus aureus strains as a cause of healthcare-associated infection","volume":"79","author":"Otter","year":"2011","journal-title":"J Hosp Infect"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B35","doi-asserted-by":"crossref","first-page":"e00054.","DOI":"10.1128\/mBio.00054-15","article-title":"Transmission and microevolution of USA300 MRSA in U.S. households: evidence from whole-genome sequencing","volume":"6","author":"Alam","year":"2015","journal-title":"MBio"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B36","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1093\/jac\/dks245","article-title":"Shift in dominant hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) clones over time","volume":"67","author":"Knight","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B37","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1469-0691.2004.01047.x","article-title":"Evaluation of the Vitek 2 system for identification and antimicrobial susceptibility testing of Staphylococcus spp","volume":"11","author":"Nonhoff","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B38","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10156-006-0502-7","article-title":"Characterization of oxacillin-susceptible mecA-positive Staphylococcus aureus: a new type of MRSA","volume":"13","author":"Hososaka","year":"2007","journal-title":"J Infect Chemother"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B39","doi-asserted-by":"crossref","first-page":"3946","DOI":"10.1128\/JCM.39.11.3946-3951.2001","article-title":"Methicillin-resistant Staphylococcus aureus: comparison of susceptibility testing methods and analysis of mecA-positive susceptible strains","volume":"39","author":"Sakoulas","year":"2001","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180313122435_dkx200-B40","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1093\/jac\/dkv119","article-title":"Within-host diversity of MRSA antimicrobial resistances","volume":"70","author":"Stanczak-Mrozek","year":"2015","journal-title":"J Antimicrob Chemother"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/72\/9\/2461\/24332472\/dkx200.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T12:26:42Z","timestamp":1520944002000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/72\/9\/2461\/3920571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,3]]},"references-count":40,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,7,3]]},"published-print":{"date-parts":[[2017,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkx200","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,9]]},"published":{"date-parts":[[2017,7,3]]}}}