{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:01:56Z","timestamp":1791414116722,"version":"4.3.3"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,1]]},"DOI":"10.1093\/jac\/dkx239","type":"journal-article","created":{"date-parts":[[2017,7,25]],"date-time":"2017-07-25T19:09:59Z","timestamp":1501009799000},"page":"2787-2791","source":"Crossref","is-referenced-by-count":46,"title":["Plazomicin activity against polymyxin-resistant Enterobacteriaceae, including MCR-1-producing isolates"],"prefix":"10.1093","volume":"72","author":[{"given":"Val\u00e9rie","family":"Denervaud-Tendon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn E","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M","family":"Krause","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Nordmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,8,10]]},"reference":[{"key":"key\n\t\t\t\t20171107090715_dkx239-B1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1128\/CMR.00064-16","article-title":"Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes","volume":"30","year":"2017","journal-title":"Clin Microbiol Rev"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijantimicag.2014.02.016","article-title":"Colistin resistance in Klebsiella pneumoniae","volume":"44","year":"2014","journal-title":"Int J Antimicrob Agents"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/jac\/dku323","article-title":"The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae","volume":"70","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B4","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1128\/AAC.05055-14","article-title":"Heteroresistance to colistin in Klebsiella pneumoniae associated with alterations in the PhoPQ regulatory system","volume":"59","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"16","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B6","article-title":"Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016","volume":"21","year":"2016","journal-title":"Euro Surveill"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S1473-3099(16)00006-2","article-title":"Plasmid-mediated carbapenem and colistin resistance in a clinical isolate of Escherichia coli","volume":"16","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B8","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1093\/cid\/ciw124","article-title":"Plasmid-mediated colistin-resistant Escherichia coli in bacteremia in Switzerland","volume":"62","year":"2016","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B9","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S1473-3099(16)00007-4","article-title":"Co-occurrence of extended spectrum \u03b2-lactamase and MCR-1 encoding genes on plasmids","volume":"16","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B10","doi-asserted-by":"crossref","first-page":"5208","DOI":"10.1128\/AAC.00869-16","article-title":"Association between the presence of aminoglycoside-modifying enzymes and in vitro activity of gentamicin, tobramycin, amikacin, and plazomicin against Klebsiella pneumoniae carbapenemase- and extended-spectrum-\u03b2-lactamase-producing Enterobacter species","volume":"60","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B11","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1128\/MMBR.51.4.439-457.1987","article-title":"Bacterial uptake of aminoglycoside antibiotics","volume":"51","year":"1987","journal-title":"Microbiol Rev"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B12","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1093\/jac\/dkx154","article-title":"Hafnia, an enterobacterial genus naturally resistant to colistin revealed by three susceptibility testing methods","volume":"72","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B13","volume-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically\u2014Tenth Edition: Approved Standard M07-10","author":"Clinical and Laboratory Standards Institute","year":"2015"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B14","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Fourth Informational Supplement M100-S24","author":"Clinical and Laboratory Standards Institute","year":"2014"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B15","author":"EUCAST","year":"2017"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B16","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.diagmicrobio.2011.08.016","article-title":"Updated multiplex polymerase chain reaction for detection of 16S rRNA methylases: high prevalence among NDM-1 producers","volume":"71","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B17","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","article-title":"Multiplex PCR for detection of acquired carbapenemase genes","volume":"70","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B18","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.idc.2016.02.011","article-title":"Aminoglycoside resistance: the emergence of acquired 16S ribosomal RNA methyltransferases","volume":"30","year":"2016","journal-title":"Infect Dis Clin North Am"},{"key":"key\n\t\t\t\t20171107090715_dkx239-B19","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1007\/s10096-010-1004-1","article-title":"Distribution of 16S rRNA methylases among different species of Gram-negative bacilli with high-level resistance to aminoglycosides","volume":"29","year":"2010","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/72\/10\/2787\/21587612\/dkx239.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T10:14:30Z","timestamp":1602584070000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/jac\/article\/72\/10\/2787\/4080303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,10]]},"references-count":19,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,8,10]]},"published-print":{"date-parts":[[2017,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkx239","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,10]]},"published":{"date-parts":[[2017,8,10]]}}}