{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:41:13Z","timestamp":1774582873485,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"DOI":"10.1093\/jac\/dkx276","type":"journal-article","created":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T19:14:03Z","timestamp":1499973243000},"page":"3172-3176","source":"Crossref","is-referenced-by-count":7,"title":["Risk of HIV transmission during combined ART initiation for HIV-infected persons with severe immunosuppression"],"prefix":"10.1093","volume":"72","author":[{"given":"V","family":"Supervie","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique (IPLESP UMRS 1136), 56 bd Vincent Auriol, F75013 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Assoumou","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique (IPLESP UMRS 1136), 56 bd Vincent Auriol, F75013 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Breban","sequence":"additional","affiliation":[{"name":"Institut Pasteur, UEME, F75015 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Lert","sequence":"additional","affiliation":[{"name":"INSERM CESP U1018, H\u00f4pital Paul-Brousse, 94800 Villejuif, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Costagliola","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique (IPLESP UMRS 1136), 56 bd Vincent Auriol, F75013 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Pialoux","sequence":"additional","affiliation":[{"name":"H\u00f4pital Tenon, APHP, Service des Maladies Infectieuses et Tropicales, F75020 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Landman","sequence":"additional","affiliation":[{"name":"Bichat Claude Bernard, APHP, Maladies Infectieuses, F75018 Paris, France"},{"name":"Institut de M\u00e9decine et d\u2019Epid\u00e9miologie Appliqu\u00e9es, UMR 1137, Univ Paris Diderot, Sorbonne Paris Cit\u00e9, F75018 Paris, France"},{"name":"Institut de M\u00e9decine et d\u2019Epid\u00e9miologie Appliqu\u00e9es, UMR 1137, INSERM, F75018 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M","family":"Girard","sequence":"additional","affiliation":[{"name":"Institut de M\u00e9decine et d\u2019Epid\u00e9miologie Appliqu\u00e9es, UMR 1137, INSERM, F75018 Paris, France"},{"name":"Saint Antoine, APHP, Maladies Infectieuses, F75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Slama","sequence":"additional","affiliation":[{"name":"H\u00f4pital Tenon, APHP, Service des Maladies Infectieuses et Tropicales, F75020 Paris, France"},{"name":"H\u00f4tel Dieu, APHP, Service de th\u00e9rapeutique en immuno-infectiologie, F75004 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the IMEA 040 DATA Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Members of the IMEA 040 DATA Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Cabi\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Abel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Hochedez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandrine","family":"Pierre-Fran\u00e7ois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beno\u00eet","family":"Roz\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Lupin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Katlama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc Antoine","family":"Valentin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte","family":"Autran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assia","family":"Samri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sidonie","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Genevi\u00e8ve","family":"Marcelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Landman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e9ronique","family":"Joly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z\u00e9lie","family":"Julia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanislas","family":"Harent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Papot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao-Chau","family":"Phung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Peytavin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick L\u00ea","family":"Minh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agathe","family":"Rami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myriam","family":"Diemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maguy","family":"Parrinello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Cahitte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Mortier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Pialoux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"L\u2019Yavanc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Le Loup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Bonnard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie Gis\u00e8le","family":"Lebrette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Chas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Berrebi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nad\u00e8ge","family":"Velazquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Adda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudine","family":"Duvivier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Touam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Lortholary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michka","family":"Shoai-Tehrani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Rouzaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Denes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Ducroux-Roubertou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne","family":"Durox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Genet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Philippe","family":"Rogez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Rogez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Pascual","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliette","family":"Pavie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erila","family":"Bourzam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugues","family":"Auma\u00eetre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milagros","family":"Ferreyra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Saada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martine","family":"Malet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christia","family":"Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Honore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Zamord","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huguette","family":"Berthe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Landowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"de Truchis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Perre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre-Marie","family":"Girard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Valin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline","family":"Campa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9n\u00e9dicte","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Luc","family":"Meynard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mich\u00e8le","family":"Pauchard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Surgers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,8,14]]},"reference":[{"key":"key\n\t\t\t\t20180328162404_dkx276-B1","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMoa1600693","article-title":"Antiretroviral therapy for the prevention of HIV-1 transmission","volume":"375","author":"Cohen","year":"2016","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B2","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/QAI.0000000000001158","article-title":"Treatment as prevention: characterization of partner infections in the HIV Prevention Trials Network 052 Trial","volume":"74","author":"Eshleman","year":"2017","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B3","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJMoa1506816","article-title":"Initiation of antiretroviral therapy in early asymptomatic HIV infection","volume":"373","author":"Insight Start Study Group","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B4","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1056\/NEJMoa1507198","article-title":"A trial of early antiretrovirals and isoniazid preventive therapy in Africa","volume":"373","author":"Temprano ANRS Study Group","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B5","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1093\/cid\/cit724","article-title":"Advanced HIV disease at entry into HIV care and initiation of antiretroviral therapy during 2006-2011: findings from four sub-Saharan African countries","volume":"58","author":"Lahuerta","year":"2014","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B6","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2015.20.47.30070","article-title":"Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013","volume":"20","author":"Late presenters working group in COHERE in EuroCoord","year":"2015","journal-title":"Euro Surveill"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B7","author":"Khatchatourian"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B8","doi-asserted-by":"crossref","first-page":"867","DOI":"10.3851\/IMP2531","article-title":"Impact of pre-therapy viral load on virological response to modern first-line HAART","volume":"18","author":"Santoro","year":"2013","journal-title":"Antivir Ther"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B9","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1056\/NEJM200003303421303","article-title":"Viral load and heterosexual transmission of human immunodeficiency virus type 1","volume":"342","author":"Quinn","year":"2000","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B10","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/QAI.0000000000001019","article-title":"HIV transmission risk persists during the first 6\u2009months of antiretroviral therapy","volume":"72","author":"Mujugira","year":"2016","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B11","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1093\/jac\/dkw103","article-title":"Efficacy and safety of once-daily ritonavir-boosted atazanavir or darunavir in combination with a dual nucleos(t)ide analogue backbone in HIV-1-infected combined ART (cART)-naive patients with severe immunosuppression: a 48\u2009week, non-comparative, randomized, multicentre trial (IMEA 040 DATA trial)","volume":"71","author":"Slama","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B12","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0140-6736(08)61115-0","article-title":"Relation between HIV viral load and infectiousness: a model-based analysis","volume":"372","author":"Wilson","year":"2008","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/cid\/ciu223","article-title":"Heterosexual risk of HIV transmission per sexual act under combined antiretroviral therapy: systematic review and Bayesian modeling","volume":"59","author":"Supervie","year":"2014","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B14","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S0277-9536(96)00258-4","article-title":"Effectiveness of condoms in preventing HIV transmission","volume":"44","author":"Pinkerton","year":"1997","journal-title":"Soc Sci Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B15","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1056\/NEJMoa1506273","article-title":"On-demand preexposure prophylaxis in men at high risk for HIV-1 infection","volume":"373","author":"Molina","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328162404_dkx276-B16","author":"Molina"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/72\/11\/3172\/21359411\/dkx276.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T02:50:13Z","timestamp":1569811813000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/72\/11\/3172\/4082647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,14]]},"references-count":16,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,8,14]]},"published-print":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkx276","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,11]]},"published":{"date-parts":[[2017,8,14]]}}}