{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:40:20Z","timestamp":1790692820325,"version":"4.1.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"4","funder":[{"DOI":"10.13039\/501100001665","name":"French National Research Agency","doi-asserted-by":"publisher","award":["ANR-10-LABX-33"],"award-info":[{"award-number":["ANR-10-LABX-33"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"DOI":"10.1093\/jac\/dkx519","type":"journal-article","created":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T22:05:47Z","timestamp":1515708347000},"page":"900-908","source":"Crossref","is-referenced-by-count":54,"title":["Evaluation of the rapid carbapenem inactivation method (rCIM): a phenotypic screening test for carbapenemase-producing Enterobacteriaceae"],"prefix":"10.1093","volume":"73","author":[{"given":"M\u0103d\u0103lina-Maria","family":"Muntean","sequence":"first","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"The \u2018Carol Davila\u2019 University of Medicine and Pharmacy, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei-Alexandru","family":"Muntean","sequence":"additional","affiliation":[{"name":"The \u2018Carol Davila\u2019 University of Medicine and Pharmacy, Bucharest, Romania"},{"name":"Department of Pneumology, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauraine","family":"Gauthier","sequence":"additional","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bic\u00eatre, France"},{"name":"Joint Research Unit EERA \u00ab Evolution and Ecology of Resistance to Antibiotics \u00bb, Institut Pasteur \u2013 APHP - Universit\u00e9 Paris Paris-Sud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Creton","sequence":"additional","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bic\u00eatre, France"},{"name":"Joint Research Unit EERA \u00ab Evolution and Ecology of Resistance to Antibiotics \u00bb, Institut Pasteur \u2013 APHP - Universit\u00e9 Paris Paris-Sud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garance","family":"Cotellon","sequence":"additional","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bic\u00eatre, France"},{"name":"Joint Research Unit EERA \u00ab Evolution and Ecology of Resistance to Antibiotics \u00bb, Institut Pasteur \u2013 APHP - Universit\u00e9 Paris Paris-Sud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mircea Ioan","family":"Popa","sequence":"additional","affiliation":[{"name":"The \u2018Carol Davila\u2019 University of Medicine and Pharmacy, Bucharest, Romania"},{"name":"The \u2018Cantacuzino\u2019 National Research Institute, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9my A","family":"Bonnin","sequence":"additional","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bic\u00eatre, France"},{"name":"Joint Research Unit EERA \u00ab Evolution and Ecology of Resistance to Antibiotics \u00bb, Institut Pasteur \u2013 APHP - Universit\u00e9 Paris Paris-Sud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9937-9572","authenticated-orcid":false,"given":"Thierry","family":"Naas","sequence":"additional","affiliation":[{"name":"Research Unit EA7361 \u2018Structure, dynamic, function and expression of broad spectrum \u03b2-lactamases\u2019, Faculty of Medicine, Universit\u00e9 Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Department of Bacteriology-Hygiene, Bic\u00eatre Hospital, Assistance Publique - H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"},{"name":"Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bic\u00eatre, France"},{"name":"Joint Research Unit EERA \u00ab Evolution and Ecology of Resistance to Antibiotics \u00bb, Institut Pasteur \u2013 APHP - Universit\u00e9 Paris Paris-Sud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,1,16]]},"reference":[{"key":"key\n\t\t\t\t20180316035334_dkx519-B1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","article-title":"The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria","volume":"9","author":"Nordmann","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S1473-3099(13)70190-7","article-title":"Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases","volume":"13","author":"Munoz-Price","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B3","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1093\/infdis\/jiw282","article-title":"The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace","volume":"215","author":"Logan","year":"2017","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B4","doi-asserted-by":"crossref","first-page":"895","DOI":"10.3389\/fmicb.2016.00895","article-title":"Global dissemination of carbapenemase-producing Klebsiella pneumoniae: epidemiology, genetic context, treatment options, and detection methods","volume":"7","author":"Lee","year":"2016","journal-title":"Front Microbiol"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B5","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1097\/CCM.0000000000001028","article-title":"The association between colonization with carbapenemase-producing Enterobacteriaceae and overall ICU mortality: an observational cohort study","volume":"43","author":"Dautzenberg","year":"2015","journal-title":"Crit Care Med"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B6","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1128\/AAC.01020-07","article-title":"Predictors of carbapenem-resistant Klebsiella pneumoniae acquisition among hospitalized adults and effect of acquisition on mortality","volume":"52","author":"Schwaber","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1469-0691.2011.03478.x","article-title":"Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections","volume":"18","author":"Ben-David","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.molmed.2012.03.003","article-title":"Carbapenem resistance in Enterobacteriaceae: here is the storm!","volume":"18","author":"Nordmann","year":"2012","journal-title":"Trends Mol Med"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B9","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.3201\/eid1710.110655","article-title":"Global spread of carbapenemase-producing Enterobacteriaceae","volume":"17","author":"Nordmann","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B10","doi-asserted-by":"crossref","first-page":"249856.","DOI":"10.1155\/2014\/249856","article-title":"Worldwide dissemination of the NDM-type carbapenemases in Gram-negative bacteria","volume":"2014","author":"Dortet","year":"2014","journal-title":"Biomed Res Int"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B11","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/1469-0691.12719","article-title":"The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide","volume":"20","author":"Nordmann","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ijantimicag.2017.03.012","article-title":"Carbapenem-resistant Enterobacteriaceae in the community: a scoping review","volume":"50","author":"Kelly","year":"2017","journal-title":"Int J Antimicrob Agents"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B13","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/1469-0691.12678","article-title":"Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories","volume":"20","author":"Hrab\u00e1k","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B14","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1128\/JCM.03318-14","article-title":"Evaluation of a new phenotypic OXA-48 disk test for differentiation of OXA-48 carbapenemase-producing Enterobacteriaceae clinical isolates","volume":"53","author":"Tsakris","year":"2015","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B15","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1128\/JCM.03467-14","article-title":"Efficient detection of carbapenemase activity in Enterobacteriaceae by matrix-assisted laser desorption ionization-time of flight mass spectrometry in less than 30 minutes","volume":"53","author":"Lasserre","year":"2015","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B16","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1093\/jac\/dkv213","article-title":"Evaluation of the RAPIDEC\u00ae CARBA NP, the rapid CARB Screen\u00ae and the Carba NP test for biochemical detection of carbapenemase-producing Enterobacteriaceae","volume":"70","author":"Dortet","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B17","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1093\/jac\/dkv468","article-title":"A two-centre evaluation of RAPIDEC\u00ae CARBA NP for carbapenemase detection in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp","volume":"71","author":"Kabir","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B18","doi-asserted-by":"crossref","first-page":"e0123690.","DOI":"10.1371\/journal.pone.0123690","article-title":"The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in Gram-negative rods","volume":"10","author":"Van der Zwaluw","year":"2015","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B19","doi-asserted-by":"crossref","first-page":"6437","DOI":"10.1128\/AAC.01395-12","article-title":"Rapid identification of carbapenemase types in Enterobacteriaceae and Pseudomonas spp. by using a biochemical test","volume":"56","author":"Dortet","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B20","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1093\/jac\/dkw058","article-title":"Prospective evaluation of the OXA-48 K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases","volume":"71","author":"Dortet","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B21","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/jac\/dkv472","article-title":"Evaluation of two new commercial immunochromatographic assays for the rapid detection of OXA-48 and KPC carbapenemases from cultured bacteria","volume":"71","author":"Glupczynski","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B22","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.mimet.2011.09.011","article-title":"Development of an immunochromatographic assay for diagnosing the production of IMP-type metallo-\u03b2-lactamases that mediate carbapenem resistance in Pseudomonas","volume":"87","author":"Kitao","year":"2011","journal-title":"J Microbiol Methods"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B23","doi-asserted-by":"crossref","first-page":"3832","DOI":"10.1128\/AAC.00517-16","article-title":"Improvement of the Xpert Carba-R Kit for the detection of carbapenemase-producing Enterobacteriaceae","volume":"60","author":"Dortet","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B24","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1093\/jac\/dku571","article-title":"Evaluation of three commercial assays for rapid detection of genes encoding clinically relevant carbapenemases in cultured bacteria","volume":"70","author":"Findlay","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B25","doi-asserted-by":"crossref","first-page":"5574","DOI":"10.1128\/AAC.00425-15","article-title":"Development of a novel real-time PCR assay with high-resolution melt analysis to detect and differentiate OXA-48-like \u03b2-lactamases in carbapenem-resistant Enterobacteriaceae","volume":"59","author":"Hemarajata","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B26","doi-asserted-by":"crossref","first-page":"e0170769.","DOI":"10.1371\/journal.pone.0170769","article-title":"Retrospective and prospective evaluation of the Carbapenem inactivation method for the detection of carbapenemase-producing Enterobacteriaceae","volume":"12","author":"Gauthier","year":"2017","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B27","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00818-17","article-title":"OXA-244-producing Escherichia coli isolates: a challenge for clinical microbiology laboratories","volume":"61","author":"Hoyos-Mallecot","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B28","doi-asserted-by":"crossref","first-page":"7100","DOI":"10.1128\/AAC.01512-15","article-title":"Dissemination of carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania","volume":"59","author":"Dortet","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B29","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: the versatile \u03b2-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B30","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1128\/AAC.02522-13","article-title":"Class D \u03b2-lactamases: are they all carbapenemases?","volume":"58","author":"Antunes","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B31","doi-asserted-by":"crossref","first-page":"78.","DOI":"10.1186\/s12879-016-2174-y","article-title":"Development of an algorithm for phenotypic screening of carbapenemase-producing Enterobacteriaceae in the routine laboratory","volume":"17","author":"Robert","year":"2017","journal-title":"BMC Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B32","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/0974-777X.176149","article-title":"Laboratory detection and clinical implication of oxacillinase-48 like carbapenemase: the hidden threat","volume":"8","author":"Bakthavatchalam","year":"2016","journal-title":"J Global Infect Dis"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B33","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.2174\/1389450117666160310144501","article-title":"Structural and functional aspects of class A carbapenemases","volume":"17","author":"Naas","year":"2016","journal-title":"Curr Drug Targets"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B34","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1093\/jac\/dkx089","article-title":"Prospective evaluation of the OKN K-SeT assay, a new multiplex immunochromatographic test for the rapid detection of OXA-48-like, KPC and NDM carbapenemases","volume":"72","author":"Glupczynski","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B35","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1128\/JCM.00193-17","article-title":"The modified carbapenem inactivation method (mCIM) for phenotypic detection of carbapenemase production among Enterobacteriaceae","volume":"55","author":"Pierce","year":"2017","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180316035334_dkx519-B36","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.mimet.2016.11.013","article-title":"Evaluation of the modified carbapenem inactivation method and sodium mercaptoacetate-combination method for the detection of metallo-\u03b2-lactamase production by carbapenemase-producing Enterobacteriaceae","volume":"132","author":"Yamada","year":"2017","journal-title":"J Microbiol Methods"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/73\/4\/900\/24269645\/dkx519.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,16]],"date-time":"2018-03-16T03:54:04Z","timestamp":1521172444000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/73\/4\/900\/4812663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,16]]},"references-count":36,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,1,16]]},"published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkx519","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,4]]},"published":{"date-parts":[[2018,1,16]]}}}