{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:58:04Z","timestamp":1788325084211,"version":"build-2803163510"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T00:00:00Z","timestamp":1527120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100003670","name":"National Evidence-based Healthcare Collaborating Agency","doi-asserted-by":"publisher","award":["NA15\u2013001"],"award-info":[{"award-number":["NA15\u2013001"]}],"id":[{"id":"10.13039\/501100003670","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,1]]},"DOI":"10.1093\/jac\/dky168","type":"journal-article","created":{"date-parts":[[2018,4,18]],"date-time":"2018-04-18T11:13:07Z","timestamp":1524049987000},"page":"2631-2642","source":"Crossref","is-referenced-by-count":53,"title":["Clinical effectiveness of carbapenems versus alternative antibiotics for treating ESBL-producing Enterobacteriaceae bacteraemia: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"73","author":[{"given":"Soo Kyung","family":"Son","sequence":"first","affiliation":[{"name":"Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea"},{"name":"Department of Health Policy and Management, Graduate School of Public Health, Korea University, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na Rae","family":"Lee","sequence":"additional","affiliation":[{"name":"Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea"},{"name":"Department of Health Policy and Management, Graduate School of Public Health, Korea University, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Hoon","family":"Ko","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Ki","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Youn","family":"Moon","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Jeong","family":"Joo","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Kangbuk Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyong Ran","family":"Peck","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Ah","family":"Park","sequence":"additional","affiliation":[{"name":"Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,5,24]]},"reference":[{"key":"key\n\t\t\t\t20180921035251_dky168-B1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0140-6736(87)90891-9","article-title":"Transferable enzymatic resistance to third-generation cephalosporins during nosocomial outbreak of multiresistant Klebsiella pneumoniae","volume":"330","author":"Brun-Buisson","year":"1987","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180921035251_dky168-B2","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF01641355","article-title":"Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens","volume":"11","author":"Knothe","year":"1983","journal-title":"Infection"},{"key":"key\n\t\t\t\t20180921035251_dky168-B3","doi-asserted-by":"crossref","first-page":"1131.","DOI":"10.1128\/AAC.33.8.1131","article-title":"Extended-spectrum \u03b2-lactamases","volume":"33","author":"Philippon","year":"1989","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B4","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/jac\/20.3.323","article-title":"Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel \u03b2-lactamase","volume":"20","author":"Sirot","year":"1987","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S1473-3099(14)70950-8","article-title":"\u03b2-lactam and \u03b2-lactamase inhibitor combinations in the treatment of extended-spectrum \u03b2-lactamase producing Enterobacteriaceae: time for a reappraisal in the era of few antibiotic options?","volume":"15","author":"Harris","year":"2015","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1473-3099(08)70041-0","article-title":"Extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae: an emerging public-health concern","volume":"8","author":"Pitout","year":"2008","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B7","author":"WHO","year":"2014"},{"key":"key\n\t\t\t\t20180921035251_dky168-B8","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.amjmed.2006.03.013","article-title":"Resistance in gram-negative bacteria: Enterobacteriaceae","volume":"119","author":"Paterson","year":"2006","journal-title":"Am J Med"},{"key":"key\n\t\t\t\t20180921035251_dky168-B9","doi-asserted-by":"crossref","first-page":"ofv050","DOI":"10.1093\/ofid\/ofv050","article-title":"Treatment options for carbapenem-resistant Enterobacteriaceae infections","volume":"2","author":"Morrill","year":"2015","journal-title":"Open Forum Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B10","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1093\/jac\/dks301","article-title":"Carbapenems versus alternative antibiotics for the treatment of bacteraemia due to Enterobacteriaceae producing extended-spectrum \u03b2-lactamases: a systematic review and meta-analysis","volume":"67","author":"Vardakas","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/jac\/dku351","article-title":"\u03b2-Lactam\/\u03b2-lactamase inhibitors versus carbapenems for the treatment of sepsis: systematic review and meta-analysis of randomized controlled trials","volume":"70","author":"Shiber","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B12","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jclinepi.2012.09.016","article-title":"Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity","volume":"66","author":"Kim","year":"2013","journal-title":"J Clin Epidemiol"},{"key":"key\n\t\t\t\t20180921035251_dky168-B13","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1177\/1536867X0800800206","article-title":"Contour-enhanced funnel plots for meta-analysis","volume":"8","author":"Palmer","year":"2008","journal-title":"Stata Journal"},{"key":"key\n\t\t\t\t20180921035251_dky168-B14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20180921035251_dky168-B15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/MD.0000000000000111","article-title":"Klebsiella pneumoniae bloodstream infection: epidemiology and impact of inappropriate empirical therapy","volume":"93","author":"Girometti","year":"2014","journal-title":"Medicine (Baltimore)"},{"key":"key\n\t\t\t\t20180921035251_dky168-B16","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ijantimicag.2013.07.018","article-title":"Epidemiology and clinical outcomes of bloodstream infections caused by extended-spectrum \u03b2-lactamase-producing Escherichia coli in patients with cancer","volume":"42","author":"Ha","year":"2013","journal-title":"Int J Antimicrob Agents"},{"key":"key\n\t\t\t\t20180921035251_dky168-B17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1413-8670(12)70310-0","article-title":"Predictors of 14-day mortality in patients with bloodstream infections caused by Enterobacteriaceae strains: a mathematical PK\/PD analysis","volume":"16","author":"Callefi","year":"2012","journal-title":"Braz J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B18","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/jac\/dkn155","article-title":"Effect of antimicrobial therapy on mortality in 377 episodes of Enterobacter spp. bacteraemia","volume":"62","author":"Marcos","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B19","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jhin.2007.10.011","article-title":"Evaluation of risk factors for the acquisition of bloodstream infections with extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella species in the intensive care unit; antibiotic management and clinical outcome","volume":"68","author":"Cordery","year":"2008","journal-title":"J Hosp Infect"},{"key":"key\n\t\t\t\t20180921035251_dky168-B20","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1080\/00365540210147516","article-title":"Bacteremia caused by Escherichia coli producing extended-spectrum \u03b2-lactamase: a case-control study of risk factors and outcomes","volume":"34","author":"Ho","year":"2002","journal-title":"Scand J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B21","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1093\/cid\/civ003","article-title":"Carbapenem therapy is associated with improved survival compared to piperacillin-tazobactam for patients with ESBL bacteremia","volume":"60","author":"Tamma","year":"2015","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B22","doi-asserted-by":"crossref","first-page":"5107","DOI":"10.1128\/AAC.00701-15","article-title":"Multicenter retrospective study of cefmetazole and flomoxef for treatment of extended-spectrum-\u03b2-lactamase-producing Escherichia coli bacteremia","volume":"59","author":"Matsumura","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B23","doi-asserted-by":"crossref","first-page":"7558","DOI":"10.1128\/AAC.01477-15","article-title":"Cefepime therapy for monomicrobial Enterobacter cloacae bacteremia: unfavorable outcome in patients infected by cefepime susceptible-dose dependent isolates","volume":"59","author":"Lee","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B24","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.ijantimicag.2015.07.020","article-title":"Comparative effectiveness of flomoxef versus carbapenems in the treatment of bacteraemia due to extended-spectrum \u03b2-lactamase-producing Escherichia coli or Klebsiella pneumoniae with emphasis on minimum inhibitory concentration of flomoxef: a retrospective study","volume":"46","author":"Lee","year":"2015","journal-title":"Int J Antimicrob Agents"},{"key":"key\n\t\t\t\t20180921035251_dky168-B25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13756-015-0055-6","article-title":"Comparable outcomes for \u03b2-lactam\/\u03b2-lactamase inhibitor combinations and carbapenems in definitive treatment of bloodstream infections caused by cefotaxime-resistant Escherichia coli or Klebsiella pneumoniae","volume":"4","author":"Harris","year":"2015","journal-title":"Antimicrob Resist Infect Control"},{"key":"key\n\t\t\t\t20180921035251_dky168-B26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijid.2014.07.012","article-title":"Nosocomial extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae bacteremia in hemodialysis patients and the implications for antibiotic therapy","volume":"28","author":"Yang","year":"2014","journal-title":"Int J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B27","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.diagmicrobio.2014.07.006","article-title":"Carbapenems and piperacillin\/tazobactam for the treatment of bacteremia caused by extended-spectrum \u03b2-lactamase\u2013producing Proteus mirabilis","volume":"80","author":"Tsai","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B28","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s10096-014-2094-y","article-title":"Alternatives to carbapenems for infections caused by ESBL-producing Enterobacteriaceae","volume":"33","author":"Pilmis","year":"2014","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B29","first-page":"293","article-title":"Role of empirical and targeted therapy in hospitalized patients with bloodstream infections caused by ESBL","volume":"26","author":"Falcone","year":"2014","journal-title":"Ann Ig"},{"key":"key\n\t\t\t\t20180921035251_dky168-B30","doi-asserted-by":"crossref","first-page":"e120","DOI":"10.1016\/j.ijid.2012.09.008","article-title":"Clinical outcome of extended-spectrum \u03b2-lactamase-producing Escherichia coli bacteremia in an area with high endemicity","volume":"17","author":"To","year":"2013","journal-title":"Int J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B31","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/cid\/cis916","article-title":"Cefepime therapy for monomicrobial bacteremia caused by cefepime-susceptible extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae: MIC matters","volume":"56","author":"Lee","year":"2013","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B32","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3109\/00365548.2013.775479","article-title":"Outcomes and risk factors for mortality in community-onset bacteremia caused by extended-spectrum \u03b2-lactamase-producing Escherichia coli, with a special emphasis on antimicrobial therapy","volume":"45","author":"Kang","year":"2013","journal-title":"Scand J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/cid\/cir790","article-title":"\u03b2-Lactam\/\u03b2-lactam inhibitor combinations for the treatment of bacteremia due to extended-spectrum \u03b2-lactamase-producing Escherichia coli: a post hoc analysis of prospective cohorts","volume":"54","author":"Rodr\u00edguez-Ba\u00f1o","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2334-12-245","article-title":"Impact of empirical treatment in extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella spp. bacteremia. A multicentric cohort study","volume":"12","author":"Peralta","year":"2012","journal-title":"BMC Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B35","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.jinf.2012.01.008","article-title":"Piperacillin\u2013tazobactam as an initial empirical therapy of bacteremia caused by extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae","volume":"64","author":"Kang","year":"2012","journal-title":"J Infect"},{"key":"key\n\t\t\t\t20180921035251_dky168-B36","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1128\/AAC.05753-11","article-title":"Bacteremia caused by extended-spectrum-\u03b2-lactamase-producing Escherichia coli sequence type ST131 and non-ST131 clones: comparison of demographic data, clinical features, and mortality","volume":"56","author":"Chung","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B37","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1128\/AAC.05419-11","article-title":"Impact of cefepime therapy on mortality among patients with bloodstream infections caused by extended-spectrum-\u03b2-lactamase-producing Klebsiella pneumoniae and Escherichia coli","volume":"56","author":"Chopra","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B38","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1590\/S1413-86702011000600016","article-title":"Klebsiella ESBL bacteremia-mortality and risk factors","volume":"15","author":"Tuon","year":"2011","journal-title":"Braz J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B39","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ijantimicag.2010.09.009","article-title":"Risk factors and outcome of extended-spectrum \u03b2-lactamase-producing Enterobacter cloacae bloodstream infections","volume":"37","author":"Qureshi","year":"2011","journal-title":"Int J Antimicrob Agents"},{"key":"key\n\t\t\t\t20180921035251_dky168-B40","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1590\/S1413-86702011000400012","article-title":"Risk factors for bloodstream infections caused by extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae","volume":"15","author":"Quirante","year":"2011","journal-title":"Braz J Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B41","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/jac\/dkq494","article-title":"Bacteraemia due to multidrug-resistant Gram-negative bacilli in cancer patients: risk factors, antibiotic therapy and outcomes","volume":"66","author":"Gudiol","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B42","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s15010-011-0201-x","article-title":"The effect of inappropriate therapy on bacteremia by ESBL-producing bacteria","volume":"39","author":"De Rosa","year":"2011","journal-title":"Infection"},{"key":"key\n\t\t\t\t20180921035251_dky168-B43","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1590\/S0037-86822010000400022","article-title":"Epidemiology of extended spectrum \u03b2-lactamase producing Enterobacter bacteremia in a Brazilian hospital","volume":"43","author":"Tuon","year":"2010","journal-title":"Rev Soc Bras Med Trop"},{"key":"key\n\t\t\t\t20180921035251_dky168-B44","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1128\/AAC.00055-10","article-title":"Bacteremia due to extended-spectrum-\u03b2-lactamase-producing Enterobacter cloacae: role of carbapenem therapy","volume":"54","author":"Lee","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-0500-3-116","article-title":"Clinical outcome of empiric antimicrobial therapy of bacteremia due to extended-spectrum \u03b2-lactamase producing Escherichia coli and Klebsiella pneumoniae","volume":"3","author":"Chaubey","year":"2010","journal-title":"BMC Res Notes"},{"key":"key\n\t\t\t\t20180921035251_dky168-B46","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1086\/588082","article-title":"Predictors of mortality from community-onset bloodstream infections due to extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae","volume":"29","author":"Apisarnthanarak","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"key":"key\n\t\t\t\t20180921035251_dky168-B47","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1128\/AAC.01509-06","article-title":"Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-\u03b2-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment","volume":"51","author":"Tumbarello","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B48","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1093\/jac\/dkl381","article-title":"Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates","volume":"58","author":"Lee","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B49","first-page":"496","article-title":"Bacteremia due to extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae other than Escherichia coli and Klebsiella","volume":"39","author":"Huang","year":"2006","journal-title":"J Microbiol Immunol Infect"},{"key":"key\n\t\t\t\t20180921035251_dky168-B50","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.diagmicrobio.2006.06.015","article-title":"Outcome of cephalosporin treatment of bacteremia due to CTX-M\u2013type extended-spectrum \u03b2-lactamase\u2013producing Escherichia coli","volume":"56","author":"Bin","year":"2006","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B51","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1128\/AAC.49.7.2598-2605.2005","article-title":"Proteus mirabilis bloodstream infections: risk factors and treatment outcome related to the expression of extended-spectrum \u03b2-lactamases","volume":"49","author":"Endimiani","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B52","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1086\/420816","article-title":"Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum \u03b2-lactamases","volume":"39","author":"Paterson","year":"2004","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180921035251_dky168-B53","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1128\/AAC.48.12.4574-4581.2004","article-title":"Bloodstream infections due to extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for mortality and treatment outcome, with special emphasis on antimicrobial therapy","volume":"48","author":"Kang","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180921035251_dky168-B54","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1007\/s00134-002-1521-1","article-title":"Extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: risk factors and clinical outcome","volume":"28","author":"Du","year":"2002","journal-title":"Intensive Care Med"},{"key":"key\n\t\t\t\t20180921035251_dky168-B55","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1055\/s-2007-996411","article-title":"Optimizing therapy for infections caused by Enterobacteriaceae producing extended-spectrum \u03b2-lactamases","volume":"28","author":"Endimiani","year":"2007","journal-title":"Semin Respir Crit Care Med"},{"key":"key\n\t\t\t\t20180921035251_dky168-B56","author":"Deeks","year":"2011"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/73\/10\/2631\/25770294\/dky168.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T19:12:44Z","timestamp":1751569964000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/73\/10\/2631\/5003037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,24]]},"references-count":56,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,5,24]]},"published-print":{"date-parts":[[2018,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dky168","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,10]]},"published":{"date-parts":[[2018,5,24]]}}}