{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:05:16Z","timestamp":1790719516536,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:00:00Z","timestamp":1548633600000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Eumedica SA","award":["CIC\/010\/2017\/FR\/GR"],"award-info":[{"award-number":["CIC\/010\/2017\/FR\/GR"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1093\/jac\/dky569","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T15:12:11Z","timestamp":1545232331000},"page":"1323-1326","source":"Crossref","is-referenced-by-count":8,"title":["Temocillin breakpoints in pyelonephritis: evaluation in a murine model due to ESBL-producing Escherichia coli clinical isolates"],"prefix":"10.1093","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7773-5695","authenticated-orcid":false,"given":"K\u00e9vin","family":"Alexandre","sequence":"first","affiliation":[{"name":"EA 2656 (GRAM 2.0), IRIB, Normandie Univ, Unirouen, Rouen, France"},{"name":"Infectious Diseases Department, Rouen University Hospital, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Soares","sequence":"additional","affiliation":[{"name":"EA 2656 (GRAM 2.0), IRIB, Normandie Univ, Unirouen, Rouen, France"},{"name":"Microbiology Department, Rouen University Hospital, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Chau","sequence":"additional","affiliation":[{"name":"INSERM, IAME, UMR 1137, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7904-9402","authenticated-orcid":false,"given":"Bruno","family":"Fantin","sequence":"additional","affiliation":[{"name":"INSERM, IAME, UMR 1137, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Caron","sequence":"additional","affiliation":[{"name":"EA 2656 (GRAM 2.0), IRIB, Normandie Univ, Unirouen, Rouen, France"},{"name":"Infectious Diseases Department, Rouen University Hospital, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7301-2614","authenticated-orcid":false,"given":"Manuel","family":"Etienne","sequence":"additional","affiliation":[{"name":"EA 2656 (GRAM 2.0), IRIB, Normandie Univ, Unirouen, Rouen, France"},{"name":"Infectious Diseases Department, Rouen University Hospital, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,1,25]]},"reference":[{"key":"2019042309335970600_dky569-B1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s40262-017-0584-7","article-title":"Pharmacokinetics and pharmacodynamics of temocillin","volume":"57","author":"Alexandre","year":"2018","journal-title":"Clin Pharmacokinet"},{"key":"2019042309335970600_dky569-B2","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1093\/jac\/dku465","article-title":"Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration","volume":"70","author":"Laterre","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0732-8893(84)90023-3","article-title":"Temocillin: in vitro activity against 734 selected clinical isolates, including \u03b2-lactamase-producing strains","volume":"2","author":"Fuchs","year":"1984","journal-title":"Diagn Microbiol Infect Dis"},{"key":"2019042309335970600_dky569-B4","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/jac\/dkm179","article-title":"Temocillin susceptibility by BSAC methodology","volume":"60","author":"Andrews","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B5","first-page":"33","volume-title":"CASFM\/EUCAST","year":"2017"},{"key":"2019042309335970600_dky569-B6","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1093\/jac\/dku542","article-title":"Activity of temocillin in a murine model of urinary tract infection due to Escherichia coli producing or not producing the ESBL CTX-M-15","volume":"70","author":"Soubirou","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B7","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1093\/jac\/dkw066","article-title":"Activity of temocillin in a lethal murine model of infection of intra-abdominal origin due to KPC-producing Escherichia coli","volume":"71","author":"Alexandre","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/1758-2229.12019","article-title":"The Clermont Escherichia coli phylo-typing method revisited: improvement of specificity and detection of new phylo-groups","volume":"5","author":"Clermont","year":"2013","journal-title":"Environ Microbiol Rep"},{"key":"2019042309335970600_dky569-B9","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1128\/JCM.02130-10","article-title":"Comparison of nine phenotypic methods for detection of extended-spectrum \u03b2-lactamase production by Enterobacteriaceae","volume":"49","author":"Garrec","year":"2011","journal-title":"J Clin Microbiol"},{"key":"2019042309335970600_dky569-B10","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1128\/IAI.01329-12","article-title":"Fitness, stress resistance, and extraintestinal virulence in Escherichia coli","volume":"81","author":"Bleibtreu","year":"2013","journal-title":"Infect Immun"},{"key":"2019042309335970600_dky569-B11","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1128\/AAC.06233-11","article-title":"Cefoxitin as an alternative to carbapenems in a murine model of urinary tract infection due to Escherichia coli harboring CTX-M-15-type extended-spectrum \u03b2-lactamase","volume":"56","author":"Lepeule","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"2019042309335970600_dky569-B12","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/jac\/dkm467","article-title":"Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection","volume":"61","author":"De Jongh","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B13","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1093\/jac\/dkr317","article-title":"Temocillin use in England: clinical and microbiological efficacies in infections caused by extended-spectrum and\/or derepressed AmpC \u03b2-lactamase-producing Enterobacteriaceae","volume":"66","author":"Balakrishnan","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"2019042309335970600_dky569-B14","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1093\/jac\/dky101","article-title":"Temocillin against Enterobacteriaceae isolates from community-acquired urinary tract infections: low rate of resistance and good accuracy of routine susceptibility testing methods","volume":"73","author":"Alexandre","year":"2018","journal-title":"J Antimicrob Chemother"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/74\/5\/1323\/28501348\/dky569.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T09:37:40Z","timestamp":1556012260000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/74\/5\/1323\/5301655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,25]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,1,25]]},"published-print":{"date-parts":[[2019,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dky569","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,5]]},"published":{"date-parts":[[2019,1,25]]}}}