{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T14:26:02Z","timestamp":1775571962572,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T00:00:00Z","timestamp":1551139200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["204566\/Z\/16\/Z"],"award-info":[{"award-number":["204566\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/R014590\/1"],"award-info":[{"award-number":["MR\/R014590\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000270","name":"Natural Environment Research Council","doi-asserted-by":"publisher","award":["NE\/P001165\/1"],"award-info":[{"award-number":["NE\/P001165\/1"]}],"id":[{"id":"10.13039\/501100000270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012147","name":"Royal Brompton & Harefield NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012147","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Allergic bronchopulmonary aspergillosis (ABPA) can accelerate lung function decline in patients with cystic fibrosis (CF). Antifungal medication can be used in addition to systemic corticosteroid treatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Patients and methods<\/jats:title>\n                  <jats:p>We evaluated Aspergillus-specific IgE and the use of therapeutic drug monitoring of triazoles in a retrospective analysis of 32 patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There was a significant reduction in Aspergillus IgE with posaconazole but not with other triazoles (P\u205f=\u205f0.026). Aspergillus IgE levels were inversely correlated with the therapeutic drug level of posaconazole.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>These data suggest that posaconazole is better than comparator azoles at decreasing serological response to Aspergillus and that this response was better with therapeutic levels of posaconazole.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jac\/dkz075","type":"journal-article","created":{"date-parts":[[2019,2,3]],"date-time":"2019-02-03T23:07:01Z","timestamp":1549235221000},"page":"1701-1703","source":"Crossref","is-referenced-by-count":34,"title":["Posaconazole for the treatment of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis"],"prefix":"10.1093","volume":"74","author":[{"given":"J","family":"Periselneris","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Nwankwo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Schelenz","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Armstrong-James","sequence":"additional","affiliation":[{"name":"National Heart & Lung Institute, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,2,25]]},"reference":[{"key":"2019121022400453500_dkz075-B1","first-page":"863","article-title":"Aspergillosis and atopy in cystic fibrosis","volume":"120","author":"Nelson","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"2019121022400453500_dkz075-B2","first-page":"1035","article-title":"Aspergillus\/allergic bronchopulmonary aspergillosis in an Irish cystic fibrosis population: a diagnostically challenging entity","volume":"53","author":"Chotirmall","year":"2008","journal-title":"Respir Care"},{"key":"2019121022400453500_dkz075-B3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1164\/rccm.200603-423OC","article-title":"Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis","volume":"174","author":"Kraemer","year":"2006","journal-title":"Am J Respir Crit Care 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