{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T14:20:11Z","timestamp":1763389211401,"version":"3.37.3"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"DOI":"10.1093\/jac\/dkz132","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T08:10:29Z","timestamp":1553242229000},"page":"2009-2018","source":"Crossref","is-referenced-by-count":2,"title":["Association between polymorphisms in MRE11 and HIV-1 susceptibility and AIDS progression in a northern Chinese MSM population"],"prefix":"10.1093","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6392-3871","authenticated-orcid":false,"given":"Chang","family":"Liu","sequence":"first","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0098-4551","authenticated-orcid":false,"given":"Yuandong","family":"Qiao","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidan","family":"Xu","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawei","family":"Wu","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingbu","family":"Mei","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuelong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaili","family":"Wang","sequence":"additional","affiliation":[{"name":"Infectious Disease Hospital of Heilongjiang Province, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyan","family":"Li","sequence":"additional","affiliation":[{"name":"Editorial Department of International Journal of Genetics, Harbin Medical University, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueyuan","family":"Jia","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiming","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wu","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjing","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songbin","family":"Fu","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, China"},{"name":"Key Laboratory of Medical Genetics, (Harbin Medical University), Heilongjiang Higher Education Institutions, 157 Baojian Road, Nangang District, Harbin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"2019062107503993500_dkz132-B1","doi-asserted-by":"crossref","first-page":"6639","DOI":"10.1038\/sj.onc.1206815","article-title":"Pathologic aspects of AIDS malignancies","volume":"22","author":"Bellan","year":"2003","journal-title":"Oncogene"},{"key":"2019062107503993500_dkz132-B2","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1002\/cncr.25547","article-title":"Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States","volume":"117","author":"Simard","year":"2011","journal-title":"Cancer"},{"key":"2019062107503993500_dkz132-B3","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/nsr\/nwv060","article-title":"MSM and HIV-1 infection in China","volume":"2","author":"Shang","year":"2015","journal-title":"Nat Sci Rev"},{"key":"2019062107503993500_dkz132-B4","doi-asserted-by":"crossref","first-page":"1071.","DOI":"10.1038\/nature08467","article-title":"The DNA-damage response in human biology and disease","volume":"461","author":"Jackson","year":"2009","journal-title":"Nature"},{"key":"2019062107503993500_dkz132-B5","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/S1097-2765(00)80097-0","article-title":"The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks","volume":"1","author":"Paull","year":"1998","journal-title":"Mol Cell"},{"key":"2019062107503993500_dkz132-B6","doi-asserted-by":"crossref","first-page":"35458","DOI":"10.1074\/jbc.M105482200","article-title":"DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex","volume":"276","author":"Trujillo","year":"2001","journal-title":"J Biol Chem"},{"key":"2019062107503993500_dkz132-B7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nrm3047","article-title":"The MRE11 complex: starting from the ends","volume":"12","author":"Stracker","year":"2011","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2019062107503993500_dkz132-B8","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0092-8674(00)81547-0","article-title":"The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder","volume":"99","author":"Stewart","year":"1999","journal-title":"Cell"},{"key":"2019062107503993500_dkz132-B9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11060-015-1892-0","article-title":"Genetic variations in the homologous recombination repair pathway genes modify risk of glioma","volume":"126","author":"Zhang","year":"2016","journal-title":"J Neurooncol"},{"key":"2019062107503993500_dkz132-B10","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s10549-009-0518-7","article-title":"Genetic variation in genes interacting with BRCA1\/2 and risk of breast cancer in the Cypriot population","volume":"121","author":"Loizidou","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"2019062107503993500_dkz132-B11","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.1093\/hmg\/ddv102","article-title":"FGFR2 regulates Mre11 expression and double-strand break repair via the MEK\u2013ERK\u2013POU1F1 pathway in breast tumorigenesis","volume":"24","author":"Huang","year":"2015","journal-title":"Hum Mol Genet"},{"key":"2019062107503993500_dkz132-B12","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.molonc.2008.09.007","article-title":"Aberrations of the MRE11\u2013RAD50\u2013NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene","volume":"2","author":"Bartkova","year":"2008","journal-title":"Mol Oncol"},{"key":"2019062107503993500_dkz132-B13","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s10549-016-4034-2","article-title":"Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer","volume":"161","author":"Kim","year":"2017","journal-title":"Breast Cancer Res Treat"},{"key":"2019062107503993500_dkz132-B14","doi-asserted-by":"crossref","first-page":"69.","DOI":"10.1186\/1471-2350-9-69","article-title":"Analysis of variants in DNA damage signalling genes in bladder cancer","volume":"9","author":"Choudhury","year":"2008","journal-title":"BMC Med Genet"},{"key":"2019062107503993500_dkz132-B15","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s12185-017-2263-8","article-title":"Recent advances in the study of immunodeficiency and DNA damage response","volume":"106","author":"Morio","year":"2017","journal-title":"Int J Hematol"},{"key":"2019062107503993500_dkz132-B16","doi-asserted-by":"crossref","first-page":"5689","DOI":"10.1093\/nar\/gkw274","article-title":"The structure of ends determines the pathway choice and Mre11 nuclease dependency of DNA double-strand break repair","volume":"44","author":"Liao","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"2019062107503993500_dkz132-B17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.mrfmmm.2017.07.011","article-title":"Regulation of repair pathway choice at two-ended DNA double-strand breaks","volume":"803\u2013805","author":"Shibata","year":"2017","journal-title":"Mutat Res"},{"key":"2019062107503993500_dkz132-B18","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.molcel.2013.11.003","article-title":"DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities","volume":"53","author":"Shibata","year":"2014","journal-title":"Mol Cell"},{"key":"2019062107503993500_dkz132-B19","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.dnarep.2010.10.001","article-title":"Mre11\u2013Rad50\u2013Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks","volume":"9","author":"Williams","year":"2010","journal-title":"DNA Repair (Amst)"},{"key":"2019062107503993500_dkz132-B20","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1158\/0008-5472.CAN-05-3144","article-title":"HIV-1 Vpr induces DNA double-strand breaks","volume":"66","author":"Tachiwana","year":"2006","journal-title":"Cancer Res"},{"key":"2019062107503993500_dkz132-B21","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1080\/15384101.2017.1312225","article-title":"Deficiency in DNA damage response, a new characteristic of cells infected with latent HIV-1","volume":"16","author":"Piekna-Przybylska","year":"2017","journal-title":"Cell Cycle"},{"key":"2019062107503993500_dkz132-B22","doi-asserted-by":"crossref","first-page":"40.","DOI":"10.1186\/s12985-015-0266-8","article-title":"BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection","volume":"12","author":"Guendel","year":"2015","journal-title":"Virol J"},{"key":"2019062107503993500_dkz132-B23","doi-asserted-by":"crossref","first-page":"21.","DOI":"10.1186\/1742-4690-10-21","article-title":"DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition","volume":"10","author":"Koyama","year":"2013","journal-title":"Retrovirology"},{"key":"2019062107503993500_dkz132-B24","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.7150\/ijbs.10366","article-title":"Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination","volume":"10","author":"Zhang","year":"2014","journal-title":"Int J Biol Sci"},{"key":"2019062107503993500_dkz132-B25","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/sj.onc.1209831","article-title":"HIV-1 Vpr induces ATM-dependent cellular signal with enhanced homologous recombination","volume":"26","author":"Nakai-Murakami","year":"2007","journal-title":"Oncogene"},{"key":"2019062107503993500_dkz132-B26","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1038\/sj.onc.1207417","article-title":"HIV-1 Tat increases cell survival in response to cisplatin by stimulating Rad51 gene expression","volume":"23","author":"Chipitsyna","year":"2004","journal-title":"Oncogene"},{"key":"2019062107503993500_dkz132-B27","doi-asserted-by":"crossref","first-page":"438","DOI":"10.4161\/cc.8.3.7642","article-title":"Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope","volume":"8","author":"Seror","year":"2009","journal-title":"Cell Cycle"},{"key":"2019062107503993500_dkz132-B28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.meegid.2016.04.016","article-title":"The polymorphisms of MSH6 gene are associated with AIDS progression in a northern Chinese population","volume":"42","author":"Wang","year":"2016","journal-title":"Infect Genet Evol"},{"key":"2019062107503993500_dkz132-B29","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1093\/carcin\/bgt094","article-title":"Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population","volume":"34","author":"Li","year":"2013","journal-title":"Carcinogenesis"},{"key":"2019062107503993500_dkz132-B30","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1080\/10428190600909743","article-title":"Haplotypic variation in MRE11, RAD50 and NBS1 and risk of non-Hodgkin\u2019s lymphoma","volume":"47","author":"Rollinson","year":"2006","journal-title":"Leuk Lymphoma"},{"key":"2019062107503993500_dkz132-B31","doi-asserted-by":"crossref","first-page":"11070","DOI":"10.1128\/JVI.78.20.11070-11076.2004","article-title":"APOBEC3G genetic variants and their influence on the progression to AIDS","volume":"78","author":"An","year":"2004","journal-title":"J Virol"},{"key":"2019062107503993500_dkz132-B32","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3109\/13550284.2010.499891","article-title":"Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood\u2013brain barrier dysfunction: implications for HIV-1-associated neurocognitive disorder","volume":"16","author":"Gandhi","year":"2010","journal-title":"J Neurovirol"},{"key":"2019062107503993500_dkz132-B33","doi-asserted-by":"crossref","first-page":"i25","DOI":"10.1093\/jrr\/rrw034","article-title":"The role of the Mre11\u2013Rad50\u2013Nbs1 complex in double-strand break repair\u2014facts and myths","volume":"57","author":"Takeda","year":"2016","journal-title":"J Radiat Res"},{"key":"2019062107503993500_dkz132-B34","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.chom.2008.10.004","article-title":"Genome-scale RNAi screen for host factors required for HIV replication","volume":"4","author":"Zhou","year":"2008","journal-title":"Cell Host Microbe"},{"key":"2019062107503993500_dkz132-B35","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.cell.2008.07.032","article-title":"Global analysis of host\u2013pathogen interactions that regulate early-stage HIV-1 replication","volume":"135","author":"Konig","year":"2008","journal-title":"Cell"},{"key":"2019062107503993500_dkz132-B36","doi-asserted-by":"crossref","first-page":"114.","DOI":"10.1186\/1742-4690-6-114","article-title":"DNA double strand break repair enzymes function at multiple steps in retroviral infection","volume":"6","author":"Sakurai","year":"2009","journal-title":"Retrovirology"},{"key":"2019062107503993500_dkz132-B37","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0042-6822(03)00455-0","article-title":"Roles of host cell factors in circularization of retroviral DNA","volume":"314","author":"Kilzer","year":"2003","journal-title":"Virology"},{"key":"2019062107503993500_dkz132-B38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s10549-008-0084-4","article-title":"DNA-repair genetic polymorphisms and risk of breast cancer in Cyprus","volume":"115","author":"Loizidou","year":"2009","journal-title":"Breast Cancer Res Treat"},{"key":"2019062107503993500_dkz132-B39","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1007\/s00438-014-0983-5","article-title":"Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes and risk of breast cancer in China","volume":"290","author":"Wu","year":"2015","journal-title":"Mol Genet Genomics"},{"key":"2019062107503993500_dkz132-B40","doi-asserted-by":"crossref","first-page":"452.","DOI":"10.1186\/s12885-018-4360-3","article-title":"Genetic variants in ATM, H2AFX and MRE11 genes and susceptibility to breast cancer in the Polish population","volume":"18","author":"Podralska","year":"2018","journal-title":"BMC Cancer"},{"key":"2019062107503993500_dkz132-B41","first-page":"184","article-title":"Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study","volume":"3","author":"Pellatt","year":"2012","journal-title":"Int J Mol Epidemiol Genet"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/advance-article-pdf\/doi\/10.1093\/jac\/dkz132\/28434180\/dkz132.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/74\/7\/2009\/28851719\/dkz132.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T07:51:18Z","timestamp":1561103478000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article\/74\/7\/2009\/5464314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,15]]},"references-count":41,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,4,15]]},"published-print":{"date-parts":[[2019,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkz132","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"type":"print","value":"0305-7453"},{"type":"electronic","value":"1460-2091"}],"subject":[],"published-other":{"date-parts":[[2019,7]]},"published":{"date-parts":[[2019,4,15]]}}}