{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:06:06Z","timestamp":1791482766453,"version":"4.3.4"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Primary Health Care Region Sk\u00e5ne"},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["Dnr 2020-05689"],"award-info":[{"award-number":["Dnr 2020-05689"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Escherichia coli, the most common bacterium causing urinary tract infections (UTIs), is increasingly reported as resistant to multiple antibiotics. Swedish surveillance data from hospital and primary health care (PHC) report a 17%\u201319% prevalence of resistance to ciprofloxacin in E. coli from urine cultures in men over 20\u2005years of age. Surveillance data may include nosocomial infections. However, few studies have described resistance in E. coli in men with community-acquired UTI in PHC. We aimed to describe the microbiological results, including antibiotic resistance in E. coli, in men with lower UTI (LUTI) attending PHC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective study based on information from electronic medical records, we included patients from 289 PHC centres. For all men aged 18\u201379\u2005years diagnosed with LUTI in PHC from January 2012 to December 2015, we extracted data on age, UTI diagnosis and results from urine cultures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 17\u200a987 episodes of lower UTI were identified. E. coli was detected in 62% of positive cultures and 63% of detected E. coli isolates were susceptible to all tested antimicrobials. Resistance in E. coli to the first-choice antibiotics pivmecillinam and nitrofurantoin were 2% and 1%, respectively. Resistance to ciprofloxacin was 9%, and to trimethoprim it was 17%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Resistance levels for ciprofloxacin in E. coli among men with LUTI in PHC were lower than in surveillance data. The results of this study point to the importance of surveillance of resistance in urine samples from patients with LUTI in PHC in order to choose the right empirical antibiotic treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jacamr\/dlae214","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T07:31:49Z","timestamp":1734420709000},"source":"Crossref","is-referenced-by-count":4,"title":["Bacterial growth and antimicrobial resistance in urinary\n                    <i>Escherichia coli<\/i>\n                    isolates among men with lower UTI in Swedish primary healthcare: retrospective data over a 4\u2005year period"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9510-7473","authenticated-orcid":false,"given":"Helena","family":"Kornf\u00e4lt Isberg","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Family Medicine Malm\u00f6, Lund University , Malm\u00f6 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7928-9555","authenticated-orcid":false,"given":"Martin","family":"Sundqvist","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Clinical Microbiology, Faculty of Medicine and Health, \u00d6rebro University , \u00d6rebro ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Melander","sequence":"additional","affiliation":[{"name":"Regional Center for Communicable Disease Control , Region Sk\u00e5ne, Malm\u00f6 ,","place":["Sweden"]},{"name":"Department of Translational Medicine, Lund University , Malm\u00f6 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Beckman","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Family Medicine Malm\u00f6, Lund University , Malm\u00f6 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Hedin","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Family Medicine Malm\u00f6, Lund University , Malm\u00f6 ,","place":["Sweden"]},{"name":"Futurum, Region J\u00f6nk\u00f6ping County and Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Link\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,26]]},"reference":[{"key":"2025022008180773200_dlae214-B1","article-title":"Antibiotic resistance","author":"WHO","year":"2023"},{"key":"2025022008180773200_dlae214-B2","article-title":"Antimicrobial resistance in the EU\/EEA (EARS-Net) - Annual epidemiological report","author":"ECDC","year":"2021"},{"key":"2025022008180773200_dlae214-B3","author":"L\u00e4kemedelsverket. 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