{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:10:47Z","timestamp":1758672647325,"version":"3.44.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>MSSA tricuspid valve infective endocarditis (TVIE) is associated with significant morbidity and there is not consensus surrounding the optimal duration of antibiotic therapy. We report the outcomes of treating MSSA TVIE endocarditis using a multidisciplinary team and cardiovascular infectious diseases consult service.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients were identified from the multidisciplinary endocarditis team registry in a single-centre retrospective study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Between 7 September 2021 and 7 September 2024, 34 patients, including 27 who inject drugs, with isolated native MSSA TVIE were identified. Patients received a median of 28\u2005days (IQR 11\u201341) of antibiotics and 50% transitioned to oral antibiotics for a median of 14\u2005days. There was one relapsed infection (2.9%) and one death at 90\u2005days (2.9%). There was no difference in relapsed infection or mortality at 90\u2005days for patients transitioned to oral therapy compared with IV (P\u200a=\u200a0.52).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>With a standardized approach to patient care, including a cardiovascular infectious diseases consult service and multidisciplinary team, patients with MSSA isolated TVIE without metastatic osteoarticular or spinal infections were successfully treated with antibiotic courses of \u226428\u2005days with low rates of mortality and relapsed infection at 90\u2005days.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jacamr\/dlaf171","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T14:40:23Z","timestamp":1758552023000},"source":"Crossref","is-referenced-by-count":0,"title":["Antibiotic treatment duration for isolated methicillin-susceptible <i>Staphylococcus aureus<\/i> native tricuspid valve endocarditis: a standardized multidisciplinary approach"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2603-2951","authenticated-orcid":false,"given":"Sami","family":"El-Dalati","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bennett","family":"Collis","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Medicine , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan","family":"Hall","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Medicine , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talal","family":"Alnabelsi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8256-9353","authenticated-orcid":false,"given":"Chloe","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, HCA Healthcare\/USF Morsani College of Medicine GME\/HCA Florida Trinity , Tampa, FL ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Gurley","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1583-9453","authenticated-orcid":false,"given":"Luke","family":"Strnad","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Oregon Health and Science University , Portland, OR ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Reda","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Sekela","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2087-187X","authenticated-orcid":false,"given":"Armaghan-E Rehman","family":"Mansoor","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Olafsson","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Harris","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Pharmacy , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobbi Jo","family":"Stoner","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Pharmacy , Lexington, KY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"2025092304264147900_dlaf171-B1","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1038\/s41598-020-80869-y","article-title":"Comparing right- and left sided injection-drug related infective endocarditis","volume":"11","author":"Clarelin","year":"2021","journal-title":"Sci 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