{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T22:00:12Z","timestamp":1773957612779,"version":"3.50.1"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"African Centre of Excellence for Infectious Diseases in Humans and Animals","award":["P151847"],"award-info":[{"award-number":["P151847"]}]},{"DOI":"10.13039\/100004421","name":"World Bank","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004421","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Bakground<\/jats:title>\n                    <jats:p>Salmonella spp. is a major cause of bacterial gastroenteritis worldwide borne from consuming contaminated food or water. The growing incidence of difficult-to-treat Salmonella infections has been heightened by increased AMR due to increased use of antibiotics posing acritical public health challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross-sectional study involving 205 children with AGE at Levy Mwanawasa University Teaching Hospital in Lusaka Zambia, between September 2020 and February 2021. Stool samples were collected and subjected to standard microbiological testing, serotyping, antimicrobial susceptibility testing and molecular confirmation for Salmonella spp. In addition, a questionnaire was administered to participants\u2019 guardians to determine the level of knowledge and practices towards Salmonella infections. Data analysis was performed using Microsoft Excel, GraphPad Prism and WHONET.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty Salmonella isolates were recovered from the processed stool samples (n\u200a=\u200a205), giving a 9.76% prevalence. Out of 20 Salmonella isolates identified, only four were susceptible to all tested antibiotics. Seven isolates (35%) were classified as multidrug resistant. The highest resistance was observed to trimethoprim-sulfamethoxazole (42.9%). Identified risk factors included use of untreated drinking water and suboptimal feeding practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The presence of multidrug-resistant Salmonella among paediatric patients highlights the need for strengthened AMR surveillance, antimicrobial stewardship and targeted public health interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jacamr\/dlag031","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T17:56:28Z","timestamp":1773942988000},"source":"Crossref","is-referenced-by-count":0,"title":["Antimicrobial resistance, characterization, and knowledge practices of\n                    <i>Salmonella<\/i>\n                    spp. infection in under-five children with acute gastroenteritis at Levy Mwanawasa University Teaching Hospital, Lusaka Zambia"],"prefix":"10.1093","volume":"8","author":[{"given":"Namwezi Namuchimba","family":"Kapembwa","sequence":"first","affiliation":[{"name":"Department of Disease Control, School of Veterinary Medicine, University of Zambia , Lusaka ,","place":["Zambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0731-3558","authenticated-orcid":false,"given":"Flavien Nsoni","family":"Bumbangi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Sciences, School of Medicine, Eden University , Lusaka ,","place":["Zambia"]},{"name":"Department of Nutrition, Kinshasa School of Public Health, Faculty of Medicine, University of Kinshasa , Kinshasa, Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chisanga","family":"Chipanta","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Medicine, University of Zambia , Lusaka ,","place":["Zambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaunda","family":"Yamba","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology, University Teaching Hospitals , Lusaka ,","place":["Zambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike","family":"Nundwe","sequence":"additional","affiliation":[{"name":"Department of Disease Control, School of Veterinary Medicine, University of Zambia , Lusaka ,","place":["Zambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misheck","family":"Shawa","sequence":"additional","affiliation":[{"name":"Department of Disease Control, School of Veterinary Medicine, University of Zambia , Lusaka ,","place":["Zambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Bwalya","family":"Muma","sequence":"additional","affiliation":[{"name":"Department of Disease Control, School of Veterinary Medicine, University of Zambia , Lusaka 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