{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T20:14:07Z","timestamp":1775679247507,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23AI163371"],"award-info":[{"award-number":["K23AI163371"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007812","name":"University of Washington","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007812","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Unverified drug allergies pose a significant barrier to successful antimicrobial stewardship efforts. Most delabelling efforts to date have occurred within an inpatient setting or through outpatient evaluations with an allergy specialist; limited data exist examining \u03b2-lactam allergies and delabelling efforts among diverse and underserved populations. Strategies are needed to better identify priority populations for allergy delabelling efforts and the highest-yield opportunities for intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We aimed to evaluate the prevalence of penicillin allergy labels (PALs) or cephalosporin allergy labels (CALs) among patients receiving infectious diseases (ID) specialty care across multiple academic and community-based settings and to characterize reported reactions and referral patterns to allergy specialists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional, retrospective cohort study of patients with PAL or CAL receiving care within seven outpatient specialty ID clinics and five inpatient ID consultation services within a large health system between 1 April 2021 and 31 December 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Inclusion criteria for this study were patients &amp;gt;18\u2005years old with a PAL or CAL listed in the electronic health record who received care at one of the above described clinics during the study time frame.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 4951 patients with a reported PAL or CAL, most were male (56%; n\u200a=\u200a2754), non-Hispanic (86%; n\u200a=\u200a4242) and white race (53%; n\u200a=\u200a2623), with a mean age of 48.2\u2005years. PAL and CAL rates were 7.6%\u201316.7% and 1.1%\u20135.3%, respectively, in outpatient ID clinics, and 8.8%\u201315.5% and 3.9%\u20136.1%, respectively, on inpatient ID consultation services. Of a total of 5965 PAL and 1506 CAL reported entries, most were consistent with hypersensitivity reactions (62.9% and 63.8%, respectively). There were 41.6% of patients with a PAL and 47.7% of patients with a CAL who reported isolated cutaneous symptoms only (flushing, itching, rash or urticaria). Few patients were referred to allergy specialists (7.8%) and ultimately delabelled.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High rates of penicillin and cephalosporin allergy labels, the majority of which reflect low-risk reactions, demonstrate a real ongoing need for innovative strategies to maximize delabelling efforts for patients with unverified drug allergies and infectious care needs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jacamr\/dlag033","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:51:51Z","timestamp":1772628711000},"source":"Crossref","is-referenced-by-count":0,"title":["Characterizing \u03b2-lactam allergy prevalence among patients receiving infectious disease specialty care within a large US healthcare system in Washington"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2942-3811","authenticated-orcid":false,"given":"Kelly","family":"Colas","sequence":"first","affiliation":[{"name":"Division of Allergy and Infectious Diseases, University of Washington , Seattle, WA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6849-3206","authenticated-orcid":false,"given":"Jimmy","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Allergy and Infectious Diseases, University of Washington , Seattle, WA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristine F","family":"Lan","sequence":"additional","affiliation":[{"name":"Division of Allergy and Infectious Diseases, University of Washington , Seattle, WA 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