{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:00:36Z","timestamp":1792166436956,"version":"4.4.0"},"reference-count":93,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The most frequently ordered laboratory test worldwide is the complete blood count (CBC). As clinical chemists are increasingly assigned to assist or direct laboratories outside of the traditional clinical chemistry sections, such as the automated hematology section, expertise must be established. This review article is a dedication to that ongoing effort.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Content<\/jats:title>\n                  <jats:p>In this primer, the white blood cell (WBC) test components of the CBC are introduced, followed by a discussion of the laboratory evaluation of leukopenia and leukocytosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>The laboratorian's approach to consult cases should be guided by the patient's clinical history and presentation while being able to provide key laboratory-based insights to assist in resolving result discrepancies that may otherwise go unnoticed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jalm\/jfaf004","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T11:32:03Z","timestamp":1738063923000},"page":"459-475","source":"Crossref","is-referenced-by-count":5,"title":["An Introduction to the Complete Blood Count for Clinical Chemists: White Blood Cells"],"prefix":"10.1093","volume":"10","author":[{"given":"Bremansu","family":"Osa-Andrews","sequence":"first","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida , Gainesville, FL ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8524-1281","authenticated-orcid":false,"given":"Xander M R","family":"van Wijk","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California San Francisco , San Francisco, CA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Normarie","family":"Herrera Rivera","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Division, HRP Labs , San Juan, PR ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P","family":"Seifert","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida , Gainesville, FL ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2329-2929","authenticated-orcid":false,"given":"Neil S","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida , Gainesville, FL ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9651-7754","authenticated-orcid":false,"given":"Maximo J","family":"Marin","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida , Gainesville, FL ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"2025030423062205300_jfaf004-B1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/ajcp\/aqy165","article-title":"The top 25 laboratory tests by volume and revenue in five different countries","volume":"151","author":"Horton","year":"2019","journal-title":"Am J Clin Pathol"},{"key":"2025030423062205300_jfaf004-B2","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/jalm\/jfae023","article-title":"An introduction to the complete blood count for clinical chemists: platelets","volume":"9","author":"van Wijk","year":"2024","journal-title":"J Appl Lab Med"},{"key":"2025030423062205300_jfaf004-B3","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1093\/jalm\/jfae031","article-title":"An introduction to the complete blood count for clinical chemists: red blood cells","volume":"9","author":"Marin","year":"2024","journal-title":"J Appl Lab Med"},{"key":"2025030423062205300_jfaf004-B4","author":"Cellwiki. 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