{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:34:00Z","timestamp":1792553640892,"version":"4.5.0"},"reference-count":201,"publisher":"Oxford University Press (OUP)","issue":"3","funder":[{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Surface water receives large quantities of wastes from human and animal sources, thus providing an ideal setting for the accumulation, development, and dissemination of antibiotic resistant bacteria, including extended-spectrum \u03b2-lactamase (ESBL)-producing Enterobacteriaceae. The rapid spread of ESBL-producing Enterobacteriaceae, particularly Escherichia coli and Klebsiella pneumoniae, is a growing threat to public health, and there have been increasing reports on the prevalence and abundance of ESBL-producing Enterobacteriaceae in aquatic environments all over the globe. The objective of this review is to understand the extent of ESBL-producing Enterobacteriaceae contamination in aquatic environments and to enhance our knowledge on the role of the freshwater environment as a reservoir and transmission routes for these bacteria. In this review, we present the prevalence and distribution of ESBL-producing Enterobacteriaceae and their ESBL genes in the freshwater environment, potential sources of these bacteria in the aquatic environment, as well as their potential drivers in the environment, including anthropogenic and environmental factors.<\/jats:p>","DOI":"10.1093\/jambio\/lxad034","type":"journal-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T19:30:52Z","timestamp":1676748652000},"source":"Crossref","is-referenced-by-count":58,"title":["Freshwater environment as a reservoir of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae"],"prefix":"10.1093","volume":"134","author":[{"given":"Sohyun","family":"Cho","sequence":"first","affiliation":[{"name":"U.S. Department of Agriculture, Agricultural Research Service, U.S. National Poultry Research Center , Poultry Microbiological Safety and Processing Research Unit, Athens, GA 30605 , USA"},{"name":"Oak Ridge Institute for Science and Education , Oak Ridge, TN 37830 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene R","family":"Jackson","sequence":"additional","affiliation":[{"name":"U.S. Department of Agriculture, Agricultural Research Service, U.S. National Poultry Research Center , Poultry Microbiological Safety and Processing Research Unit, Athens, GA 30605 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan G","family":"Frye","sequence":"additional","affiliation":[{"name":"U.S. Department of Agriculture, Agricultural Research Service, U.S. National Poultry Research Center , Poultry Microbiological Safety and Processing Research Unit, Athens, GA 30605 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,20]]},"reference":[{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1128\/AAC.02689-13","article-title":"Enterobacteriaceae with extended-spectrum- and pAmpC-type beta-lactamase-encoding genes isolated from freshwater fish from two lakes in Switzerland","volume":"58","author":"Abgottspon","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"885","DOI":"10.3390\/microorganisms8060885","article-title":"a One Health comparative assessment of antimicrobial resistance in generic and extended-spectrum cephalosporin-resistant Escherichia coli from beef production, sewage and clinical settings","volume":"8","author":"Adator","year":"2020","journal-title":"Microorganisms"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1007\/s11356-017-0686-7","article-title":"Extended spectrum beta-lactamase (ESBL)-producing bacteria isolated from hospital wastewaters, rivers and aquaculture sources in Nigeria","volume":"25","author":"Adelowo","year":"2018","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1128\/JCM.01915-15","article-title":"Prevalence, risk factors, and transmission dynamics of extended-spectrum-beta-lactamase-producing Enterobacteriaceae: a national survey of cattle farms in Israel in 2013","volume":"53","author":"Adler","year":"2015","journal-title":"J Clin Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"601","DOI":"10.2166\/wh.2022.216","article-title":"Antibiotic resistance pattern and molecular detection of ESBL-associated genes in E. Coli from surface and wastewater of Islamabad capital territory, Pakistan","volume":"20","author":"Ahsan","year":"2022","journal-title":"J Water Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"14847","DOI":"10.1038\/s41598-019-51421-4","article-title":"Occurrence of bacterial markers and antibiotic resistance genes in sub-Saharan rivers receiving animal farm wastewaters","volume":"9","author":"Al\u00a0Salah","year":"2019","journal-title":"Sci Rep"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s00248-015-0718-0","article-title":"Wild birds, frequent carriers of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli of CTX-M and SHV-12 types","volume":"72","author":"Alcala","year":"2016","journal-title":"Microb Ecol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.envint.2018.05.011","article-title":"Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR","volume":"117","author":"An","year":"2018","journal-title":"Environ Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"101547","DOI":"10.1016\/j.tmaid.2019.101547","article-title":"Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in a population of Dutch travellers: a cross-sectional study","volume":"33","author":"Arcilla","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1264\/jsme2.ME17050","article-title":"Occurrence of extended-spectrum and AmpC-type beta-lactamase genes in Escherichia coli isolated from water environments in Northern Thailand","volume":"32","author":"Assawatheptawee","year":"2017","journal-title":"Microbes Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1080\/09603123.2021.1940884","article-title":"Detection of extended spectrum beta-lactamase genes in strains of Escherichia coli and Klebsiella pneumoniae isolated from recreational water and tertiary hospital waste water in Zaria, Nigeria","volume":"32","author":"Atta","year":"2021","journal-title":"Int J Environ Health Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0190380","DOI":"10.1371\/journal.pone.0190380","article-title":"ESBL-producing Escherichia coli in Swedish gulls-a case of environmental pollution from humans?","volume":"12","author":"Atterby","year":"2017","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13756-017-0208-x","article-title":"the threat of antimicrobial resistance in developing countries: causes and control strategies","volume":"6","author":"Ayukekbong","year":"2017","journal-title":"Antimicrob Resist Infect Control"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/j.jsps.2020.10.009","article-title":"Pharmaceutical disposal facilitates the mobilization of resistance determinants among microbiota of polluted environment","volume":"28","author":"Azam","year":"2020","journal-title":"Saudi Pharm J"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.scitotenv.2014.09.084","article-title":"Distribution and molecular characterization of genes encoding CTX-M and AmpC beta-lactamases in Escherichia coli isolated from an Indian urban aquatic environment","volume":"505","author":"Bajaj","year":"2015","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3389\/fmicb.2020.00108","article-title":"Genome-based analysis of extended-spectrum beta-lactamase-producing Escherichia coli in the aquatic environment and Nile perch (Lates niloticus) of Lake Victoria, Tanzania","volume":"11","author":"Baniga","year":"2020","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3390\/tropicalmed6020105","article-title":"Extended spectrum beta-lactamase Escherichia coli in river waters collected from two cities in Ghana, 2018\u20132020","volume":"6","author":"Banu","year":"2021","journal-title":"Trop Med Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.4269\/ajtmh.18-0726","article-title":"Antibiotic resistance in Enterobacteriaceae from surface waters in urban Brazil highlights the risks of poor sanitation","volume":"100","author":"Bartley","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.3390\/ijerph19084736","article-title":"Removal of extended-spectrum beta-lactamase-producing Escherichia coli, ST98, in water for human consumption by black ceramic water filters in low-income Ecuadorian highlands","volume":"19","author":"Bastidas-Caldes","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"747","DOI":"10.3390\/microorganisms8050747","article-title":"Antimicrobial resistance traits ofEscherichia coli isolated from dairy manure and freshwater ecosystems are similar to one another but differ from associated clinical isolates","volume":"8","author":"Beattie","year":"2020","journal-title":"Microorganisms"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.scitotenv.2016.01.042","article-title":"Characteristics of extended-spectrum beta-lactamase (ESBL)- and pAmpC beta-lactamase-producing Enterobacteriaceae of water samples in Tunisia","volume":"550","author":"Ben\u00a0Said","year":"2016","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"6551","DOI":"10.1128\/AAC.00933-15","article-title":"the human gut microbiome as a transporter of antibiotic resistance genes between continents","volume":"59","author":"Bengtsson-Palme","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/nrmicro3439","article-title":"Tackling antibiotic resistance: the environmental framework","volume":"13","author":"Berendonk","year":"2015","journal-title":"Nat Rev Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"dlac048","DOI":"10.1093\/jacamr\/dlac048","article-title":"Comparison of the global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli between healthcare and community settings: a systematic review and meta-analysis","volume":"4","author":"Bezabih","year":"2022","journal-title":"JAC Antimicrob Resist"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/jac\/dkaa399","article-title":"the global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli in the community","volume":"76","author":"Bezabih","year":"2021","journal-title":"J Antimicrob Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.vetmic.2014.03.007","article-title":"Prevalence and characteristics of ESBL-producing E. Coli in Dutch recreational waters influenced by wastewater treatment plants","volume":"171","author":"Blaak","year":"2014","journal-title":"Vet Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0135402","DOI":"10.1371\/journal.pone.0135402","article-title":"Distribution, numbers and diversity of ESBL-producing E. Coli in the poultry farm environment","volume":"10","author":"Blaak","year":"2015","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.3389\/fmicb.2018.03239","article-title":"Dissemination of CTX-M-producing Escherichia coli in freshwater fishes from a French watershed (Burgundy)","volume":"9","author":"Bollache","year":"2018","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e5958","DOI":"10.1371\/journal.pone.0005958","article-title":"Dissemination of Escherichia coli with CTX-M type ESBL between humans and yellow-legged gulls in the south of France","volume":"4","author":"Bonnedahl","year":"2009","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1093\/jac\/dkq222","article-title":"Characterization, and comparison, of human clinical and black-headed gull (Larus ridibundus) extended-spectrum \u03b2 -lactamase-producing bacterial isolates from Kalmar, on the southeast coast of Sweden","volume":"65","author":"Bonnedahl","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1179\/2047773214Y.0000000148","article-title":"Prevalence of antibiotic resistant bacteria in healthy adults, foods, food animals, and the environment in selected areas in Thailand","volume":"108","author":"Boonyasiri","year":"2014","journal-title":"Pathog Glob Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1093\/cid\/ciu190","article-title":"Wastewater treatment plants release large amounts of extended-spectrum beta-lactamase-producing Escherichia coli into the environment","volume":"58","author":"Brechet","year":"2014","journal-title":"Clin Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijantimicag.2004.02.015","article-title":"a view on antimicrobial resistance in developing countries and responsible risk factors","volume":"24","author":"Byarugaba","year":"2004","journal-title":"Int J Antimicrob Agents"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e127","DOI":"10.1016\/S1473-3099(16)00100-6","article-title":"Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance","volume":"16","author":"Cabello","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"519169","DOI":"10.3389\/fmicb.2020.519169","article-title":"Distribution of beta-lactamase producing gram-negative bacterial isolates in Isabela river of Santo Domingo, Dominican Republic","volume":"11","author":"Calderon","year":"2020","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.3389\/fmicb.2017.02232","article-title":"Occurrence of extended spectrum beta-lactamases, KPC-Type, and MCR-1.2-producing Enterobacteriaceae from wells, river water, and wastewater treatment plants in Oltrepo Pavese area, northern Italy","volume":"8","author":"Caltagirone","year":"2017","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3389\/fmicb.2012.00110","article-title":"CTX-M enzymes: origin and diffusion","volume":"3","author":"Canton","year":"2012","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"dlab092","DOI":"10.1093\/jacamr\/dlab092","article-title":"Extended-spectrum beta-lactamases: an update on their characteristics, epidemiology and detection","volume":"3","author":"Castanheira","year":"2021","journal-title":"JAC Antimicrob Resist"},{"key":"2023030721021618100_","article-title":"Antibiotic use in the United States, 2017: progress and opportunities","author":"Centers for Disease Control and Prevention (CDC)","year":"2017"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","DOI":"10.15620\/cdc:82532","article-title":"Antibiotic resistance threats in the United States, 2019","author":"Centers for Disease Control and Prevention (CDC)","year":"2019"},{"key":"2023030721021618100_","article-title":"ResistanceMap: antibiotic use","author":"Center for Disease Dynamics, Economics and Policy (CDDEP)"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1365-2672.2011.05072.x","article-title":"Multiresistance, beta-lactamase-encoding genes and bacterial diversity in hospital wastewater in Rio de Janeiro, Brazil","volume":"111","author":"Chagas","year":"2011","journal-title":"J Appl Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"115502","DOI":"10.1016\/j.envpol.2020.115502","article-title":"Co-occurrence of multidrug resistance, beta-lactamase and plasmid mediated AmpC genes in bacteria isolated from river Ganga, northern India","volume":"267","author":"Chaturvedi","year":"2020","journal-title":"Environ Pollut"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"129693","DOI":"10.1016\/j.chemosphere.2021.129693","article-title":"Dissemination of antibiotic resistance genes, mobile genetic elements, and efflux genes in anthropogenically impacted riverine environments","volume":"273","author":"Chaturvedi","year":"2021","journal-title":"Chemosphere"},{"key":"2023030721021618100_","first-page":"1375060","article-title":"Occurrence of beta-lactamase-producing gram-negative bacterial isolates in water sources in Cali city, Colombia","volume":"2019","author":"Chavez","year":"2019","journal-title":"Int J Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1016\/j.envpol.2010.03.023","article-title":"the profile of antibiotics resistance and integrons of extended-spectrum beta-lactamase producing thermotolerant coliforms isolated from the Yangtze River basin in Chongqing","volume":"158","author":"Chen","year":"2010","journal-title":"Environ Pollut"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1128\/AEM.03222-15","article-title":"Characteristics of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli strains isolated from multiple rivers in southern Taiwan","volume":"82","author":"Chen","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0197005","DOI":"10.1371\/journal.pone.0197005","article-title":"Prevalence and characterization of Escherichia coliisolated from the upper oconee watershed in Northeast Georgia","volume":"13","author":"Cho","year":"2018","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.3390\/ijerph16193761","article-title":"Genetic characterization of antimicrobial-resistant Escherichia coli isolated from a mixed-use watershed in northeast Georgia, USA","volume":"16","author":"Cho","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3389\/fmicb.2015.00803","article-title":"Potential impacts of aquatic pollutants: sub-clinical antibiotic concentrations induce genome changes and promote antibiotic resistance","volume":"6","author":"Chow","year":"2015","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jes.2020.05.030","article-title":"a survey of sub-inhibitory concentrations of antibiotics in the environment","volume":"99","author":"Chow","year":"2021","journal-title":"J Environ Sci (China)"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e398","DOI":"10.1016\/S2542-5196(18)30186-4","article-title":"Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis","volume":"2","author":"Collignon","year":"2018","journal-title":"Lancet Planet Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ecoenv.2016.10.031","article-title":"Characterization of CTX-M enzymes, quinolone resistance determinants, and antimicrobial residues from hospital sewage, wastewater treatment plant, and river water","volume":"136","author":"Conte","year":"2017","journal-title":"Ecotoxicol Environ Saf"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/jac\/dkl415","article-title":"Detection of Escherichia coli harbouring extended-spectrum beta-lactamases of the CTX-M, TEM and SHV classes in faecal samples of wild animals in Portugal","volume":"58","author":"Costa","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0210686","DOI":"10.1371\/journal.pone.0210686","article-title":"High prevalence and diversity of extended-spectrum beta-lactamase and emergence of OXA-48 producing enterobacterales in wildlife in Catalonia","volume":"14","author":"Darwich","year":"2019","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.envpol.2017.04.036","article-title":"Rainfall increases the abundance of antibiotic resistance genes within a riverine microbial community","volume":"226","author":"Di\u00a0Cesare","year":"2017","journal-title":"Environ Pollut"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"10153","DOI":"10.1021\/acs.est.6b02268","article-title":"Fitness and recovery of bacterial communities and antibiotic resistance genes in urban wastewaters exposed to classical disinfection treatments","volume":"50","author":"Di\u00a0Cesare","year":"2016","journal-title":"Environ Sci Technol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"135","DOI":"10.7705\/biomedica.v39i0.4391","article-title":"Detection of multidrug-resistant Enterobacteriaceae isolated from river waters flowing to the Guanabara Bay and from clinical samples of hospitals in Rio de Janeiro, Brazil","volume":"39","author":"Dias\u00a0Goncalves","year":"2019","journal-title":"Biomedica"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"604567","DOI":"10.3389\/fmicb.2021.604567","article-title":"Isolation of ciprofloxacin and ceftazidime-resistant enterobacterales from vegetables and river water is strongly associated with the season and the sample type","volume":"12","author":"D\u00edaz-Gavidia","year":"2021","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1111\/j.1365-2672.2009.04155.x","article-title":"Antibiotic-resistant Salmonella and Escherichia coliisolates with integrons and extended-spectrum beta-lactamases in surface water and sympatric black-headed gulls","volume":"106","author":"Dolejska","year":"2009","journal-title":"J Appl Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13756-016-0108-5","article-title":"Quantitative evaluation of extended-spectrum beta-lactamase-producing Escherichia coli strains in the wastewater of a French teaching hospital and relation to patient strain","volume":"5","author":"Drieux","year":"2016","journal-title":"Antimicrob Resist Infect Control"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.scitotenv.2017.02.157","article-title":"Unexpected common occurrence of transferable extended spectrum cephalosporinase-producing Escherichia coli in Swedish surface waters used for drinking water supply","volume":"587-588","author":"Egervarn","year":"2017","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"711950","DOI":"10.3389\/fenvs.2021.711950","article-title":"the abundance of genes encoding ESBL, pAmpC and non-\u03b2-lactam resistance in multidrug-resistant Enterobacteriaceae recovered from wastewater effluents","volume":"9","author":"Fadare","year":"2021","journal-title":"Front Environ Sci"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0224861","DOI":"10.1371\/journal.pone.0224861","article-title":"Comparative distribution of extended-spectrum beta-lactamase-producing Escherichia coli from urine infections and environmental waters","volume":"14","author":"Fagerstrom","year":"2019","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"617349","DOI":"10.3389\/fmicb.2021.617349","article-title":"Clonal CTX-M-15-producing Escherichia coli ST-949 are present in German surface water","volume":"12","author":"Falgenhauer","year":"2021","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"172813","DOI":"10.1016\/j.ejphar.2019.172813","article-title":"Antimicrobial pharmaceuticals in the aquatic environment - occurrence and environmental implications","volume":"866","author":"Felis","year":"2020","journal-title":"Eur J Pharmacol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4767","DOI":"10.1128\/AEM.00798-16","article-title":"Detection of antibiotic resistance genes in source and drinking water samples from a First Nations Community in Canada","volume":"82","author":"Fernando","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.3389\/fmicb.2020.01273","article-title":"Whole genome sequencing and characterization of multidrug-resistant (MDR) bacterial strains isolated from a Norwegian university campus pond","volume":"11","author":"Finton","year":"2020","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","article-title":"2015 Summary report on antimicrobials sold or distributed for use in food-producing animals","author":"Food and Drug Administration (FDA)","year":"2016"},{"key":"2023030721021618100_","article-title":"2017 Summary report on antimicrobials sold or distributed for use in food-producing animals","author":"Food and Drug Administration (FDA)","year":"2018"},{"key":"2023030721021618100_","article-title":"2020 Summary report on antimicrobials sold or distributed for use in food-producing animals","author":"Food and Drug Administration (FDA)","year":"2021"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3389\/fmicb.2019.00364","article-title":"Extended spectrum beta-lactamase-producing gram-negative bacteria recovered from an Amazonian Lake near the city of Belem, Brazil","volume":"10","author":"Freitas","year":"2019","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"190912","DOI":"10.5696\/2156-9614-9.23.190912","article-title":"Assessment of antibiotic levels, multi-drug resistant bacteria and genetic biomarkers in the waters of the Rio Grande River between the United States-Mexico Border","volume":"9","author":"Fuentes","year":"2019","journal-title":"J Health Pollut"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4772","DOI":"10.1128\/AEM.02898-09","article-title":"Enumeration and characterization of antimicrobial-resistant Escherichia coli bacteria in effluent from municipal, hospital, and secondary treatment facility sources","volume":"76","author":"Galvin","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3389\/fmicb.2015.00313","article-title":"Application of swine manure on agricultural fields contributes to extended-spectrum beta-lactamase-producing Escherichia colispread in Tai'an, China","volume":"6","author":"Gao","year":"2015","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.3390\/ijerph120404203","article-title":"Emissions of Escherichia colicarrying extended-spectrum \u03b2-lactamase resistance from pig farms to the surrounding environment","volume":"12","author":"Gao","year":"2015","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"603578","DOI":"10.3389\/fmicb.2020.603578","article-title":"Occurrence and diversity of CTX-M-producing Escherichia coli from the Seine River","volume":"11","author":"Girlich","year":"2020","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"ofy357","DOI":"10.1093\/ofid\/ofy357","article-title":"Risk factors for community-acquired extended-spectrum beta-lactamase-producing Enterobacteriaceae infections- a retrospective study of symptomatic urinary tract infections","volume":"6","author":"Goyal","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3389\/fmicb.2011.00246","article-title":"Extended-spectrum beta-lactamases producing E. Coli in wildlife, yet another form of environmental pollution?","volume":"2","author":"Guenther","year":"2011","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","first-page":"860","article-title":"Analysis of wastewater reveals the spread of diverse extended-spectrum beta-lactamase-producing E. Coli strains in uMgungundlovu District, South Africa","volume":"10","author":"Gumede","year":"2021","journal-title":"Antibiotics (Basel, Switzerland)"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.1021\/acs.est.5b00644","article-title":"Distinguishing effects of ultraviolet exposure and chlorination on the horizontal transfer of antibiotic resistance genes in municipal wastewater","volume":"49","author":"Guo","year":"2015","journal-title":"Environ Sci Technol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0210735","DOI":"10.1371\/journal.pone.0210735","article-title":"Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia","volume":"14","author":"Guzman-Otazo","year":"2019","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3862949","DOI":"10.1155\/2019\/3862949","article-title":"Antimicrobial-resistant Escherichia coli from environmental waters in northern Colorado","volume":"2019","author":"Haberecht","year":"2019","journal-title":"J Environ Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.scitotenv.2017.09.217","article-title":"Occurrence and characteristics of extended-spectrum beta-lactamase- and carbapenemase- producing bacteria from hospital effluents in Singapore","volume":"615","author":"Haller","year":"2018","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jiac.2014.07.003","article-title":"ESBL-producing Enterobacteriaceae in environmental water in Dhaka, Bangladesh","volume":"20","author":"Haque","year":"2014","journal-title":"J Infect Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fmicb.2012.00083","article-title":"Occurrence of CTX-M producing Escherichia coli in soils, cattle, and farm environment in France (Burgundy Region)","volume":"3","author":"Hartmann","year":"2012","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"44368","DOI":"10.1007\/s11356-020-10326-w","article-title":"Genetic characterization of ESBL-producing Escherichia coli and Klebsiella pneumoniae isolated from wastewater and river water in Tunisia: predominance of CTX-M-15 and high genetic diversity","volume":"27","author":"Hassen","year":"2020","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"fiaa231","DOI":"10.1093\/femsec\/fiaa231","article-title":"Genetic characterization of extended-spectrum beta-lactamase-producing Enterobacteriaceae from a biological industrial wastewater treatment plant in Tunisia with detection of the colistin-resistance mcr-1 gene","volume":"97","author":"Hassen","year":"2021","journal-title":"FEMS Microbiol Ecol"},{"key":"2023030721021618100_","first-page":"201","article-title":"Multidrug resistance and the predominance of blaCTX-M in extended spectrum beta-lactamase-producing Enterobacteriaceae of animal and water origin","volume":"28","author":"Hassen","year":"2018","journal-title":"J Mol Microbiol Biotechnol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.3147\/jsfp.51.S75","article-title":"Spread of antibiotic and antimicrobial susceptibility of ESBL-producing Escherichia coli isolated from wild and cultured fish in the Mekong Delta, Vietnam","volume":"51","author":"Hon","year":"2016","journal-title":"Fish Pathol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.1128\/AEM.01740-13","article-title":"Molecular typing of CTX-M-producing Escherichia coli isolates from environmental water, swine feces, specimens from healthy humans, and human patients","volume":"79","author":"Hu","year":"2013","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1016\/j.watres.2011.02.026","article-title":"Inactivation and reactivation of antibiotic-resistant bacteria by chlorination in secondary effluents of a municipal wastewater treatment plant","volume":"45","author":"Huang","year":"2011","journal-title":"Water Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"fiy038","DOI":"10.1093\/femsec\/fiy038","article-title":"Host range of antibiotic resistance genes in wastewater treatment plant influent and effluent","volume":"94","author":"Hultman","year":"2018","journal-title":"FEMS Microbiol Ecol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.3390\/microorganisms9051057","article-title":"Diversity of plasmids and genes encoding resistance to extended-spectrum \u03b2-lactamase in Escherichia coli from different animal sources","volume":"9","author":"Ibekwe","year":"2021","journal-title":"Microorganisms"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1021\/es303577u","article-title":"Pathogenic Escherichia coli strains producing extended-spectrum beta-lactamases in the Yeongsan River basin of South Korea","volume":"47","author":"Jang","year":"2013","journal-title":"Environ Sci Technol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.3389\/fmicb.2019.01797","article-title":"Whole genome sequencing of extended-spectrum \u03b2-lactamase (ESBL)-producing Escherichia coliisolated from a wastewater treatment plant in China","volume":"10","author":"Jiang","year":"2019","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"849","DOI":"10.2166\/wh.2020.065","article-title":"Extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli presence in urban aquatic environments in Kanpur, India","volume":"18","author":"Johnson","year":"2020","journal-title":"J Water Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0186576","DOI":"10.1371\/journal.pone.0186576","article-title":"a comparison of extended spectrum beta-lactamase producing Escherichia coli from clinical, recreational water and wastewater samples associated in time and location","volume":"12","author":"Jorgensen","year":"2017","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.scitotenv.2017.10.312","article-title":"Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations","volume":"616-617","author":"Jutkina","year":"2018","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/cid\/ciw283","article-title":"Fecal colonization with extended-spectrum beta-lactamase-producing Enterobacteriaceae and risk factors among healthy individuals: a systematic review and metaanalysis","volume":"63","author":"Karanika","year":"2016","journal-title":"Clin Infect Dis"},{"key":"2023030721021618100_","first-page":"237","article-title":"Plasmid-mediated extended-spectrum beta-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1","volume":"201","author":"Karim","year":"2001","journal-title":"FEMS Microbiol Lett"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.tim.2017.09.005","article-title":"Antibiotic-resistance genes in waste water","volume":"26","author":"Karkman","year":"2018","journal-title":"Trends Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s12275-008-0150-y","article-title":"the identification of CTX-M-14, TEM-52, and CMY-1 enzymes in Escherichia coli isolated from the Han River in Korea","volume":"46","author":"Kim","year":"2008","journal-title":"J Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"8264","DOI":"10.3390\/ijerph18168264","article-title":"Occurrence of extended spectrum beta lactamase (ESBL) producers, quinolone and carbapenem resistant Enterobacteriaceae isolated from environmental samples along Msimbazi River basin ecosystem in Tanzania","volume":"18","author":"Kimera","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1057\/s41599-018-0152-2","article-title":"Pharming animals: a global history of antibiotics in food production (1935\u20132017)","volume":"4","author":"Kirchhelle","year":"2018","journal-title":"Palgrave Commun"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e0165820","DOI":"10.1371\/journal.pone.0165820","article-title":"Enterobacteriaceae isolated from the River Danube: antibiotic resistances, with a focus on the presence of ESBL and carbapenemases","volume":"11","author":"Kittinger","year":"2016","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1473-3099(20)30332-7","article-title":"Assessment of WHO antibiotic consumption and access targets in 76 countries, 2000\u201315: an analysis of pharmaceutical sales data","volume":"21","author":"Klein","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"E3463","DOI":"10.1073\/pnas.1717295115","article-title":"Global increase and geographic convergence in antibiotic consumption between 2000 and 2015","volume":"115","author":"Klein","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jenvman.2013.03.024","article-title":"Beta-lactamase-producing Enterobacteriaceae in hospital effluents","volume":"123","author":"Korzeniewska","year":"2013","journal-title":"J Environ Manage"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.jenvman.2013.06.051","article-title":"Extended-spectrum beta-lactamase (ESBL)-positive Enterobacteriaceae in municipal sewage and their emission to the environment","volume":"128","author":"Korzeniewska","year":"2013","journal-title":"J Environ Manage"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ecoenv.2013.01.014","article-title":"Antibiotic resistant Escherichia coli in hospital and municipal sewage and their emission to the environment","volume":"91","author":"Korzeniewska","year":"2013","journal-title":"Ecotoxicol Environ Saf"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"32111","DOI":"10.1007\/s11356-021-14178-w","article-title":"Pharmaceutical effluent: a critical link in the interconnected ecosystem promoting antimicrobial resistance","volume":"28","author":"Kotwani","year":"2021","journal-title":"Environ Sci Pollut Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/jac\/dkh325","article-title":"Resistance in the environment","volume":"54","author":"Kummerer","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.chemosphere.2008.12.006","article-title":"Antibiotics in the aquatic environment\u2014a review\u2014part II","volume":"75","author":"Kummerer","year":"2009","journal-title":"Chemosphere"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"788","DOI":"10.2166\/wh.2017.257","article-title":"Characterization of extended spectrum beta-lactamase (ESBL)-producing Escherichia coli in Asi (Orontes) River in Turkey","volume":"15","author":"Kurekci","year":"2017","journal-title":"J Water Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"110487","DOI":"10.1016\/j.envres.2020.110487","article-title":"Extended-spectrum \u03b2-lactamase-producing Escherichia coli and antimicrobial resistance in municipal and hospital wastewaters in Czech Republic: culture-based and metagenomic approaches","volume":"193","author":"Kutilova","year":"2021","journal-title":"Environ Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ijantimicag.2014.09.016","article-title":"Surveillance of antimicrobial resistance among Escherichia coli in wastewater in Stockholm during 1 year: does it reflect the resistance trends in the society?","volume":"45","author":"Kwak","year":"2015","journal-title":"Int J Antimicrob Agents"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"138129","DOI":"10.1016\/j.scitotenv.2020.138129","article-title":"Impact of anthropogenic activities on the occurrence and distribution of toxic metals, extending-spectra beta-lactamases and carbapenem resistance in sub-Saharan African urban rivers","volume":"727","author":"Laffite","year":"2020","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.2147\/IDR.S269033","article-title":"Risk factors of extended-spectrum beta-lactamases-producing Escherichia coli community acquired urinary tract infections: a systematic review","volume":"13","author":"Larramendy","year":"2020","journal-title":"Infect Drug Resist"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"20130571","DOI":"10.1098\/rstb.2013.0571","article-title":"Pollution from drug manufacturing: review and perspectives","volume":"369","author":"Larsson","year":"2014","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jhazmat.2007.07.008","article-title":"Effluent from drug manufactures contains extremely high levels of pharmaceuticals","volume":"148","author":"Larsson","year":"2007","journal-title":"J Hazard Mater"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"110037","DOI":"10.1016\/j.envres.2020.110037","article-title":"How much of antibiotics can enter surface water with treated wastewater and how it affects the resistance of waterborne bacteria: a case study of the Bialka river sewage treatment plant","volume":"191","author":"Lenart-Boron","year":"2020","journal-title":"Environ Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1007\/s11356-014-3665-2","article-title":"Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system","volume":"22","author":"Li","year":"2015","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"633","DOI":"10.3389\/fmicb.2019.00633","article-title":"the role of plasmids in the multiple antibiotic resistance transfer in ESBLs-producing Escherichia coli isolated from wastewater treatment plants","volume":"10","author":"Li","year":"2019","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"13033","DOI":"10.1007\/s11356-015-4575-7","article-title":"Spread of extended-spectrum beta-lactamase-producing Escherichia coli from a swine farm to the receiving river","volume":"22","author":"Li","year":"2015","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12866-018-1270-0","article-title":"Molecular characteristics of extended-spectrum beta-lactamase-producing Escherichia coli isolated from the rivers and lakes in Northwest China","volume":"18","author":"Liu","year":"2018","journal-title":"BMC Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.scitotenv.2016.02.103","article-title":"Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms","volume":"553","author":"Lundstrom","year":"2016","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/s41558-018-0161-6","article-title":"Antibiotic resistance increases with local temperature","volume":"8","author":"MacFadden","year":"2018","journal-title":"Nat Clim Change"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"795","DOI":"10.3390\/molecules23040795","article-title":"Antibiotic use in agriculture and its consequential resistance in environmental sources: potential public health implications","volume":"23","author":"Manyi-Loh","year":"2018","journal-title":"Molecules"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.watres.2015.09.010","article-title":"Prevalence and proliferation of antibiotic resistance genes in two municipal wastewater treatment plants","volume":"85","author":"Mao","year":"2015","journal-title":"Water Res"},{"key":"2023030721021618100_","article-title":"the ESBL tricycle AMR surveillance project: a simple, one health approach to global surveillance","author":"Matheu","year":"2017"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40793-019-0345-3","article-title":"Metagenome of a polluted river reveals a reservoir of metabolic and antibiotic resistance genes","volume":"14","author":"Mittal","year":"2019","journal-title":"Environ Microbiome"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.3389\/fmicb.2017.02476","article-title":"High prevalence of CTX-M-15-type ESBL-producing E. Coli from migratory avian species in Pakistan","volume":"8","author":"Mohsin","year":"2017","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.3389\/fmicb.2016.01862","article-title":"Predominance of CTX-M-15 among ESBL producers from environment and fish gut from the shores of Lake Victoria in Mwanza, Tanzania","volume":"7","author":"Moremi","year":"2016","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jgar.2018.10.007","article-title":"Occurrence of extended-spectrum beta-lactamase-producing bacteria in urban Clinton River habitat","volume":"16","author":"Muraleedharan","year":"2019","journal-title":"J Glob Antimicrob Resist"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Murray","year":"2022","journal-title":"Lancet"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s10661-013-3398-6","article-title":"Occurrences and fate of selected human antibiotics in influents and effluents of sewage treatment plant and effluent-receiving river Yamuna in Delhi (India)","volume":"186","author":"Mutiyar","year":"2014","journal-title":"Environ Monit Assess"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1080\/14756366.2017.1344235","article-title":"Beta-lactamase database (BLDB) - structure and function","volume":"32","author":"Naas","year":"2017","journal-title":"J Enzyme Inhib Med Chem"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.envpol.2016.12.041","article-title":"Water metagenomic analysis reveals low bacterial diversity and the presence of antimicrobial residues and resistance genes in a river containing wastewater from backyard aquacultures in the Mekong Delta, Vietnam","volume":"222","author":"Nakayama","year":"2017","journal-title":"Environ Pollut"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.scitotenv.2014.12.072","article-title":"Environmental waters and blaNDM-1 in Belgrade, Serbia: endemicity questioned","volume":"511","author":"Novovic","year":"2015","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"100803","DOI":"10.1016\/j.nmni.2020.100803","article-title":"Resistotyping and extended-spectrum beta-lactamase genes among Escherichia coli from wastewater treatment plants and recipient surface water for reuse in South Africa","volume":"38","author":"Nzima","year":"2020","journal-title":"New Microbes New Infect"},{"key":"2023030721021618100_","article-title":"Antimicrobials in agriculture and the environment: reducing unnecessary use and waste","author":"O'Neill","year":"2015"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1089\/mdr.2016.0269","article-title":"Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae from pharmaceutical wastewaters in south-western Nigeria","volume":"23","author":"Obasi","year":"2017","journal-title":"Microb Drug Resist"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.watres.2014.02.041","article-title":"High dissemination of extended-spectrum beta-lactamase-producing Enterobacteriaceae in effluents from wastewater treatment plants","volume":"56","author":"Ojer-Usoz","year":"2014","journal-title":"Water Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3201\/eid0501.990103","article-title":"Socioeconomic and behavioral factors leading to acquired bacterial resistance to antibiotics in developing countries","volume":"5","author":"Okeke","year":"1999","journal-title":"Emerg Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"67","DOI":"10.2166\/wh.2019.195","article-title":"High quantities of multidrug-resistant Escherichia coliare present in the Machangara urban river in Quito, Ecuador","volume":"18","author":"Ortega-Paredes","year":"2020","journal-title":"J Water Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.cmi.2019.02.026","article-title":"Individual- and community-level risk factors for ESBL Enterobacteriaceae colonization identified by universal admission screening in London","volume":"25","author":"Otter","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1128\/CMR.18.4.657-686.2005","article-title":"Extended-spectrum beta-lactamases: a clinical update","volume":"18","author":"Paterson","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.watres.2019.05.102","article-title":"Diversity and antibiotic resistance among Escherichia coli populations in hospital and community wastewater compared to wastewater at the receiving urban treatment plant","volume":"161","author":"Paulshus","year":"2019","journal-title":"Water Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.3390\/microorganisms8091425","article-title":"Multidrug-resistant bacteria isolated from different aquatic environments in the north of Spain and south of France","volume":"8","author":"Perez-Etayo","year":"2020","journal-title":"Microorganisms"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1128\/AEM.02761-09","article-title":"Genetic detection of extended-spectrum beta-lactamase-containing Escherichia coli isolates from birds of prey from Serra da Estrela Natural Reserve in Portugal","volume":"76","author":"Pinto","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2165\/11533040-000000000-00000","article-title":"Infections with extended-spectrum beta-lactamase-producing enterobacteriaceae: changing epidemiology and drug treatment choices","volume":"70","author":"Pitout","year":"2010","journal-title":"Drugs"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1473-3099(08)70041-0","article-title":"Extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae: an emerging public-health concern","volume":"8","author":"Pitout","year":"2008","journal-title":"Lancet Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"7439","DOI":"10.1128\/AEM.00949-08","article-title":"Seagulls of the Berlengas natural reserve of Portugal as carriers of fecal Escherichia coli harboring CTX-M and TEM extended-spectrum beta-lactamases","volume":"74","author":"Poeta","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"101815","DOI":"10.1016\/j.cimid.2022.101815","article-title":"Global epidemiology of CTX-M-type beta-lactam resistance in human and animal","volume":"86","author":"Rana","year":"2022","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1016\/j.jiph.2020.10.016","article-title":"Multilocus-based phylogenetic analysis of extended-spectrum beta-lactamase Escherichia coli O157:H7 uncovers related strains between agriculture and nearby water sources","volume":"13","author":"Raseala","year":"2020","journal-title":"J Infect Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1038\/s41467-020-15735-6","article-title":"Aquaculture at the crossroads of global warming and antimicrobial resistance","volume":"11","author":"Reverter","year":"2020","journal-title":"Nat Commun"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.scitotenv.2013.01.032","article-title":"Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review","volume":"447","author":"Rizzo","year":"2013","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4217","DOI":"10.3390\/ijerph16214217","article-title":"Comparison of culture- and quantitative PCR-based indicators of antibiotic resistance in wastewater, recycled water, and tap water","volume":"16","author":"Rocha","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","first-page":"2245","article-title":"IncI1\/ST3 and IncN\/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1\/-32 in diverse Escherichia coli clones from different piggeries","volume":"68","author":"Rodrigues","year":"2013","journal-title":"J Antimicrob Chemother"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"171","DOI":"10.2166\/washdev.2020.086","article-title":"Hospital wastewater effluent: hot spot for antibiotic resistant bacteria","volume":"10","author":"Rozman","year":"2020","journal-title":"J Water Sanit Hyg Dev"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13073-017-0471-8","article-title":"Whole genome sequencing of ESBL-producing Escherichia coli isolated from patients, farm waste and canals in Thailand","volume":"9","author":"Runcharoen","year":"2017","journal-title":"Genome Med"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.ijantimicag.2018.09.022","article-title":"Non-prescription sales of antimicrobial agents at community pharmacies in developing countries: a systematic review","volume":"52","author":"Sakeena","year":"2018","journal-title":"Int J Antimicrob Agents"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3390\/antibiotics9060286","article-title":"the gut of healthy infants in the community as a reservoir of ESBL and carbapenemase-producing bacteria","volume":"9","author":"Saleem","year":"2020","journal-title":"Antibiotics (Basel)"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"100236","DOI":"10.1016\/j.onehlt.2021.100236","article-title":"Global prevalence and molecular characterization of extended-spectrum beta-lactamase producing-Escherichia coli in dogs and cats - a scoping review and meta-analysis","volume":"12","author":"Salgado-Caxito","year":"2021","journal-title":"One Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s10661-018-6801-5","article-title":"Detection of different \u03b2-lactamases encoding genes, including bla(NDM), and plasmid-mediated quinolone resistance genes in different water sources from Brazil","volume":"190","author":"Sanchez","year":"2018","journal-title":"Environ Monit Assess"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3109\/03009734.2014.904457","article-title":"Selection of antibiotic resistance at very low antibiotic concentrations","volume":"119","author":"Sandegren","year":"2014","journal-title":"Ups J Med Sci"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e00107","DOI":"10.1128\/mSphere.00107-20","article-title":"Prevalence and characteristics of extended-spectrum-beta-lactamase-producing and carbapenemase-producing Enterobacteriaceae from freshwater fish and pork in wet markets of Hong Kong","volume":"5","author":"Sapugahawatte","year":"2020","journal-title":"mSphere"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.chemosphere.2006.03.026","article-title":"a global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment","volume":"65","author":"Sarmah","year":"2006","journal-title":"Chemosphere"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e02748","DOI":"10.1128\/AEM.02748-19","article-title":"ESKAPE bacteria and extended-spectrum-\u03b2-lactamase-producing Escherichia coli isolated from wastewater and process water from German poultry slaughterhouses","volume":"86","author":"Savin","year":"2020","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"11825","DOI":"10.1021\/acs.est.5b01888","article-title":"Fate of extended-spectrum beta-lactamase-producing Escherichia coli from faecal sources in surface water and probability of human exposure through swimming","volume":"49","author":"Schijven","year":"2015","journal-title":"Environ Sci Technol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3389\/fmicb.2019.01034","article-title":"Antibiotic resistance of E. Coli isolated from a constructed wetland dominated by a crow roost, with emphasis on ESBL and AmpC containing E. Coli","volume":"10","author":"Sen","year":"2019","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e030266","DOI":"10.1136\/bmjopen-2019-030266","article-title":"Variation of effect estimates in the analysis of mortality and length of hospital stay in patients with infections caused by bacteria-producing extended-spectrum beta-lactamases: a systematic review and meta-analysis","volume":"10","author":"Shamsrizi","year":"2020","journal-title":"BMJ Open"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"5611","DOI":"10.1007\/s13762-018-1939-9","article-title":"Co-occurrence of esbls and silver resistance determinants among bacterial isolates inhabiting polluted stretch of river Yamuna, India","volume":"16","author":"Siddiqui","year":"2018","journal-title":"Int J Environ Sci Technol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.scitotenv.2014.04.100","article-title":"Prevalence of antibiotic-resistant fecal bacteria in a river impacted by both an antibiotic production plant and urban treated discharges","volume":"488-489","author":"Sidrach-Cardona","year":"2014","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"874","DOI":"10.3390\/pathogens9110874","article-title":"Extracellular DNA (eDNA): neglected and potential sources of antibiotic resistant genes (ARGs) in the aquatic environments","volume":"9","author":"Sivalingam","year":"2020","journal-title":"Pathogens"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"622891","DOI":"10.3389\/fmicb.2021.622891","article-title":"Antibiotic resistance profiles and molecular characteristics of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae isolated from shrimp aquaculture farms in Kerala, India","volume":"12","author":"Sivaraman","year":"2021","journal-title":"Front Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"104581","DOI":"10.1016\/j.micpath.2020.104581","article-title":"Molecular assessment of antimicrobial resistance and virulence in multi drug resistant ESBL-producing Escherichia coli and Klebsiella pneumoniae from food fishes, Assam, India","volume":"149","author":"Sivaraman","year":"2020","journal-title":"Microb Pathog"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e69581","DOI":"10.1371\/journal.pone.0069581","article-title":"Risk factors for community-acquired urinary tract infections caused by ESBL-producing enterobacteriaceae\u2014a case-control study in a low prevalence country","volume":"8","author":"S\u00f8raas","year":"2013","journal-title":"PLoS One"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1089\/fpd.2011.0866","article-title":"Gilthead seabream (Sparus aurata) as carriers of SHV-12 and TEM-52 extended-spectrum beta-lactamases-containing Escherichia coli isolates","volume":"8","author":"Sousa","year":"2011","journal-title":"Foodborne Pathog Dis"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1038\/s41598-021-81315-3","article-title":"Detection and characterization of ESBL-producing Enterobacteriaceae from the gut of subsistence farmers, their livestock, and the surrounding environment in rural Nepal","volume":"11","author":"Subramanya","year":"2021","journal-title":"Sci Rep"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"4134","DOI":"10.1128\/AEM.00359-12","article-title":"Resistance to broad-spectrum antibiotics in aquatic systems: anthropogenic activities modulate the dissemination of bla(CTX-M)-like genes","volume":"78","author":"Tacao","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.watres.2017.04.073","article-title":"Characterization of OXA-48-like-producing Enterobacteriaceae isolated from river water in Algeria","volume":"120","author":"Tafoukt","year":"2017","journal-title":"Water Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.1016\/S2542-5196(17)30141-9","article-title":"Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis","volume":"1","author":"Tang","year":"2017","journal-title":"Lancet Planet Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.scitotenv.2018.07.126","article-title":"Occurrence of antibiotic residues and antibiotic-resistant bacteria in effluents of pharmaceutical manufacturers and other sources around Hanoi, Vietnam","volume":"645","author":"Thai","year":"2018","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","first-page":"14","article-title":"Isolation of extended spectrum \u03b2-lactamase (ESBL) producing bacteria from urban surface waters in Malaysia","volume":"20","author":"Tissera","year":"2013","journal-title":"Malays J Med Sci"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1126\/science.aao1495","article-title":"Reducing antimicrobial use in food animals","volume":"357","author":"Van\u00a0Boeckel","year":"2017","journal-title":"Science"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"649","DOI":"10.3201\/eid2004.131718","article-title":"High rates of antimicrobial drug resistance gene acquisition after international travel, the Netherlands","volume":"20","author":"von\u00a0Wintersdorff","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"2023030721021618100_","article-title":"WHO integrated global surveillance on ESBL-producing E. Coli using a \u201cone Health\u201d approach: implementation and opportunities","author":"World Health Organization (WHO)","year":"2021"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1128\/CMR.00023-13","article-title":"Trends in human fecal carriage of extended-spectrum beta-lactamases in the community: toward the globalization of CTX-M","volume":"26","author":"Woerther","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"2023030721021618100_","article-title":"Antimicrobial resistance: global report on surveillance","author":"World Health Organization (WHO)","year":"2014"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.chemosphere.2014.02.040","article-title":"Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river","volume":"119","author":"Xu","year":"2015","journal-title":"Chemosphere"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ecoenv.2017.04.053","article-title":"Occurrence of antimicrobial resistance bacteria in the Yodo River basin, Japan and determination of beta-lactamases producing bacteria","volume":"143","author":"Yamashita","year":"2017","journal-title":"Ecotoxicol Environ Saf"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s10646-017-1814-3","article-title":"Antibiotic resistance genes in surface water of eutrophic urban lakes are related to heavy metals, antibiotics, lake morphology and anthropic impact","volume":"26","author":"Yang","year":"2017","journal-title":"Ecotoxicol"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.scitotenv.2017.03.138","article-title":"Troubled water under the bridge: screening of River Mur water reveals dominance of CTX-M harboring Escherichia coli and for the first time an environmental VIM-1 producer in Austria","volume":"593-594","author":"Zarfel","year":"2017","journal-title":"Sci Total Environ"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"12030","DOI":"10.1007\/s11356-016-6350-9","article-title":"Fate and removal of various antibiotic resistance genes in typical pharmaceutical wastewater treatment systems","volume":"23","author":"Zhai","year":"2016","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.watres.2019.06.026","article-title":"beta-lactam resistance genes in bacteriophage and bacterial DNA from wastewater, river water, and irrigation water in Washington State","volume":"161","author":"Zhang","year":"2019","journal-title":"Water Res"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s13756-019-0590-7","article-title":"Economic burden of antibiotic resistance in ESKAPE organisms: a systematic review","volume":"8","author":"Zhen","year":"2019","journal-title":"Antimicrob Resist Infect Control"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"937","DOI":"10.3390\/ijerph18030937","article-title":"Characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolates from Jurong Lake, Singapore with whole-genome-sequencing","volume":"18","author":"Zhong","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1089\/mdr.2018.0431","article-title":"Evaluating dissemination mechanisms of antibiotic-resistant bacteria in rural environments in China by using CTX-M-producing Escherichia coli as an indicator","volume":"25","author":"Zou","year":"2019","journal-title":"Microb Drug Resist"},{"key":"2023030721021618100_","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1128\/AEM.00054-13","article-title":"Characteristics of extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae isolates from rivers and lakes in Switzerland","volume":"79","author":"Zurfluh","year":"2013","journal-title":"Appl Environ Microbiol"}],"container-title":["Journal of Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jambio\/advance-article-pdf\/doi\/10.1093\/jambio\/lxad034\/49281612\/lxad034.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jambio\/article-pdf\/134\/3\/lxad034\/49439678\/lxad034.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jambio\/article-pdf\/134\/3\/lxad034\/49439678\/lxad034.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T04:36:24Z","timestamp":1701923784000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jambio\/article\/doi\/10.1093\/jambio\/lxad034\/7049110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,20]]},"references-count":201,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,2,20]]},"published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jambio\/lxad034","relation":{},"ISSN":["1365-2672"],"issn-type":[{"value":"1365-2672","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3]]},"published":{"date-parts":[[2023,2,20]]},"article-number":"lxad034"}}