{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T20:45:56Z","timestamp":1772311556282,"version":"3.50.1"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["PDR10 E\u201326\/204.521\/2021"],"award-info":[{"award-number":["PDR10 E\u201326\/204.521\/2021"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u0131fico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["303\u00a0288\/2020-5"],"award-info":[{"award-number":["303\u00a0288\/2020-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u0131vel Superior","doi-asserted-by":"publisher","award":["88881.311598\/2018-01"],"award-info":[{"award-number":["88881.311598\/2018-01"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To evaluate the prevalence, molecular characteristics, antimicrobial susceptibility, and epithelial invasion of Streptococcus agalactiae strains isolated from pregnant women and newborns in Rio de Janeiro, Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A total of 67 S. agalactiae isolates, 48 isolates from pregnant women and 19 from neonates, were analyzed. Capsular type Ia and V were predominant (35.8%\/each). The multilocus sequence typing analysis revealed the presence of 19 STs grouped into 6 clonal complexes with prevalence of CC17\/40.3% and CC23\/34.3%. The lmb and iag virulence genes were found in 100% of isolates. Four S. agalactiae strains, belonging to CC17\/ST1249 and CC23\/ST23, were able to adhere to A549 respiratory epithelial cells. Antimicrobial resistance was verified mainly to tetracycline (85%), erythromycin (70.8%), and clindamycin (58.3%). Four S. agalactiae isolates were multidrug resistant. The resistance genes tested were found in 92.5% of isolates for tetM, 58.2% for ermB, 28.4% for mefAE, and 10.4% for tetO.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The study showed a high prevalence of virulence and antimicrobial genes in S. agalactiae strains isolated from pregnant women and newborns, supporting the idea that continued surveillance is necessary to identify risk factors and perform long-term follow-up in pregnant women and neonates in Rio de Janeiro.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jambio\/lxae200","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:09:15Z","timestamp":1723075755000},"source":"Crossref","is-referenced-by-count":4,"title":["Molecular characterization, antimicrobial resistance and invasion of epithelial cells by <i>Streptococcus agalactiae<\/i> strains isolated from colonized pregnant women and newborns in Rio de Janeiro, Brazil"],"prefix":"10.1093","volume":"135","author":[{"given":"Bruna Alves da Silva","family":"Pimentel","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Biology and Physiology of Streptococci, Institute of Biology Roberto Alcantara Gomes, Rio de Janeiro State University\u2014UERJ , Rio de Janeiro 20550-013 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamella Silva","family":"Lannes-Costa","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Physiology of Streptococci, Institute of Biology Roberto Alcantara Gomes, Rio de Janeiro State University\u2014UERJ , Rio de Janeiro 20550-013 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice Slotfeldt","family":"Viana","sequence":"additional","affiliation":[{"name":"Departamento de Microbiologia M\u00e9dica, Universidade Federal do Rio de Janeiro , Rio de Janeiro, 21941-902 RJ , 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