{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T14:15:36Z","timestamp":1783088136389,"version":"3.54.6"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T00:00:00Z","timestamp":1661731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"US Assistant Secretary for Preparedness and Response","award":["6 U3REP150548-05-08"],"award-info":[{"award-number":["6 U3REP150548-05-08"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Monkeypox virus was historically rare outside of West and Central Africa until the current 2022 global outbreak, which has required clinicians to be alert to identify individuals with possible monkeypox, institute isolation, and take appropriate next steps in evaluation and management. Clinical decision support systems (CDSS), which have been shown to improve adherence to clinical guidelines, can support frontline clinicians in applying the most current evaluation and management guidance in the setting of an emerging infectious disease outbreak when those guidelines are evolving over time. Here, we describe the rapid development and implementation of a CDSS tool embedded in the electronic health record to guide frontline clinicians in the diagnostic evaluation of monkeypox infection and triage patients with potential monkeypox infection to individualized infectious disease physician review. We also present data on the initial performance of this tool in a large integrated healthcare system.<\/jats:p>","DOI":"10.1093\/jamia\/ocac151","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T12:55:58Z","timestamp":1661345758000},"page":"2124-2127","source":"Crossref","is-referenced-by-count":12,"title":["Development and implementation of a clinical decision support system tool for the evaluation of suspected monkeypox infection"],"prefix":"10.1093","volume":"29","author":[{"given":"John S","family":"Albin","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9286-3548","authenticated-orcid":false,"given":"Jacob E","family":"Lazarus","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen M","family":"Hysell","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M","family":"Rubins","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts, USA"},{"name":"Department of Medicine, Brigham and Women\u2019s Hospital , Boston, Massachusetts, USA"},{"name":"Digital eCare, Mass General Brigham , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay","family":"Germaine","sequence":"additional","affiliation":[{"name":"Digital eCare, Mass General Brigham , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6604-6111","authenticated-orcid":false,"given":"Caitlin M","family":"Dugdale","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"},{"name":"Medical Practice Evaluation Center, Massachusetts General Hospital , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard M","family":"Heller","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth L","family":"Hohmann","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua J","family":"Baugh","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts, USA"},{"name":"Department of Emergency Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-1123","authenticated-orcid":false,"given":"Erica S","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Harvard Medical School , Boston, Massachusetts, USA"},{"name":"Digital eCare, Mass General Brigham , Boston, Massachusetts, USA"},{"name":"Department of Emergency Medicine, Massachusetts General Hospital , Boston, Massachusetts, USA"},{"name":"Regional Emerging Special Pathogens Treatment Center, Massachusetts General Hospital , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,29]]},"reference":[{"issue":"6","key":"2022111608004359000_ocac151-B1","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1056\/NEJMcpc2201244","article-title":"Case 24-2022: a 31-year-old man with perianal and penile ulcers, rectal pain, and rash","volume":"387","author":"Basgoz","year":"2022","journal-title":"N Engl J Med"},{"key":"2022111608004359000_ocac151-B2","author":"Centers for Disease Control and Prevention 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