{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T01:38:19Z","timestamp":1777772299585,"version":"3.51.4"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"United States Department of Health and Human Services, Assistant Secretary for Technology Policy"},{"DOI":"10.13039\/100005982","name":"Office of the National Coordinator for Health Information Technology","doi-asserted-by":"publisher","award":["90AX0028"],"award-info":[{"award-number":["90AX0028"]}],"id":[{"id":"10.13039\/100005982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We conducted the Clinical Registry Extraction and Data Submission (CREDS) project to evaluate the readiness of HL7 Fast Healthcare Interoperability Resources (FHIR) for provisioning data from health information systems for the American College of Cardiology Cardiac Catheterization Percutaneous Coronary Intervention (CathPCI) Registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>The CREDS project had 3 workstreams: (1) evaluation of the readiness of clinical documentation for data transforms, (2) modeling of a FHIR-based clinical workflow for registry data submission, and (3) development and demonstration of a CREDS FHIR implementation for registry data submission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 344 data concepts comprising the CathPCI Registry, only 111 (32%) were sufficiently discrete to be listed in the CathPCI Data Dictionary with a terminology mapping. Cardiologist informaticians identified an additional 42 concepts suitable for provisioning via a FHIR payload. The resulting notional workflow combined FHIR-based data assembly with manual chart abstraction of compound, summative, and complex clinical concepts. A CathPCI FHIR StructureDefinition artifact was authored, incorporated into a CREDS FHIR Implementation Guide, and balloted to Standard for Trial Use status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>CREDS demonstrated both potential and limitations for using FHIR for registry data submission. The largest technical impediment was the volume of code (&amp;gt;11\u2009000 lines) for the FHIR StructureDefinition. Lack of regularized clinical vocabularies, reliance of registries on complex clinical concepts, and absence of FHIR infrastructure must be overcome before CREDS can be used at scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CREDS demonstrated proof-of-concept FHIR-based provisioning of clinical data for registry submission. All artifacts are open source to inform others with similar interests.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jamia\/ocag029","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:27:32Z","timestamp":1771331252000},"page":"1018-1025","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the potential of fast healthcare interoperability resources for clinical registry data submission"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6231-5567","authenticated-orcid":false,"given":"James E","family":"Tcheng","sequence":"first","affiliation":[{"name":"Department of Medicine, Duke University School of Medicine , Durham, NC 27705,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Finney","sequence":"additional","affiliation":[{"name":"Leap Orbit LLC , Columbia, MD, 21046,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"Boone","sequence":"additional","affiliation":[{"name":"PointClickCare Inc. (formerly Audacious Inquiry) , Mississauga, ON, L4W0C4,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samit P","family":"Desai","sequence":"additional","affiliation":[{"name":"PointClickCare Inc. (formerly Audacious Inquiry) , Mississauga, ON, L4W0C4,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A","family":"Pyke","sequence":"additional","affiliation":[{"name":"PointClickCare Inc. (formerly Audacious Inquiry) , Mississauga, ON, L4W0C4,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandan","family":"Shanbhag","sequence":"additional","affiliation":[{"name":"American College of Cardiology , Washington, DC, 20037,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganesan","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"American College of Cardiology , Washington, DC, 20037,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Ramsing","sequence":"additional","affiliation":[{"name":"Chesapeake Regional Information System for Our Patients , Columbia, MD, 21046,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D","family":"Kelemen","sequence":"additional","affiliation":[{"name":"Chesapeake Regional Information System for Our Patients , Columbia, MD, 21046,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"2026042913021612300_ocag029-B1","doi-asserted-by":"crossref","first-page":"e0183667","DOI":"10.1371\/journal.pone.0183667","article-title":"Impact of clinical registries on quality of patient care and clinical outcomes: a systematic review","volume":"12","author":"Hoque","year":"2017","journal-title":"PLoS One"},{"key":"2026042913021612300_ocag029-B2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ijmedinf.2010.01.011","article-title":"Improving quality of care. A systematic review on how medical registries provide information feedback to health care providers","volume":"79","author":"van der Veer","year":"2010","journal-title":"Int J Med Inform."},{"key":"2026042913021612300_ocag029-B3","doi-asserted-by":"crossref","first-page":"205","DOI":"10.14797\/mdcj-16-3-205","article-title":"The role of national registries in improving quality of care and outcomes for cardiovascular disease","volume":"16","author":"Meltzer","year":"2020","journal-title":"Methodist Debakey Cardiovasc J."},{"key":"2026042913021612300_ocag029-B4","author":"National Cardiovascular Data Registry","year":"2024"},{"key":"2026042913021612300_ocag029-B5","first-page":"864","article-title":"Achieving data liquidity: lessons learned from analysis of 38 clinical registries (The Duke-Pew Data Interoperability Project)","volume":"2019","author":"Tcheng","journal-title":"AMIA Annu Symp Proc"},{"key":"2026042913021612300_ocag029-B6","first-page":"1g","article-title":"Electronic Health Record (EHR) abstraction","volume":"18","author":"Alzu\u2019bi","year":"2021","journal-title":"Perspect Health Inf Manag"},{"key":"2026042913021612300_ocag029-B7","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1377\/hlthaff.2015.1258","article-title":"US physician practices spend more than $15.4 billion annually to report quality measures","volume":"35","author":"Casalino","year":"2016","journal-title":"Health Aff (Millwood)"},{"key":"2026042913021612300_ocag029-B8","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1001\/jama.2023.7271","article-title":"The volume and cost of quality metric reporting","volume":"329","author":"Saraswathula","year":"2023","journal-title":"JAMA."},{"key":"2026042913021612300_ocag029-B9","author":"Health Information Technology for Economic and Clinical Health Act of 2009","year":"2009"},{"key":"2026042913021612300_ocag029-B10","author":"21st Century Cures Act","year":"2016"},{"key":"2026042913021612300_ocag029-B11","author":"Assistant Secretary for Technology Policy"},{"key":"2026042913021612300_ocag029-B12","author":"CRISP"},{"key":"2026042913021612300_ocag029-B13","author":"ASTP"},{"key":"2026042913021612300_ocag029-B14","author":"American College of Cardiology","year":"2025"},{"key":"2026042913021612300_ocag029-B15","author":"NCDR CathPCI Registry"},{"key":"2026042913021612300_ocag029-B16","author":"HL7 FHIR - FHIRPath Normative Release (v2.0.0)"},{"key":"2026042913021612300_ocag029-B17","author":"HL7 Confluence"},{"key":"2026042913021612300_ocag029-B18","author":"HL7 FHIR Release 5"},{"key":"2026042913021612300_ocag029-B19","author":"Clinical Registry Extraction and Data Submission Application"},{"key":"2026042913021612300_ocag029-B20","author":"HL7 FHIR"},{"key":"2026042913021612300_ocag029-B21","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1055\/s-0041-1731784","article-title":"Why is the electronic health record so challenging for research and clinical care?","volume":"60","author":"Holmes","year":"2021","journal-title":"Methods Inf Med."},{"key":"2026042913021612300_ocag029-B22","author":"HL7 FHIR"},{"key":"2026042913021612300_ocag029-B23","doi-asserted-by":"crossref","first-page":"109745","DOI":"10.1016\/j.compbiomed.2025.109745","article-title":"Towards real-world clinical data standardization: a modular FHIR-driven transformation pipeline to enhance semantic interoperability in healthcare","volume":"187","author":"Marfoglia","year":"2025","journal-title":"Comput Biol Med"},{"key":"2026042913021612300_ocag029-B24","author":"CodeX"},{"key":"2026042913021612300_ocag029-B25","author":"CodeX CardX"},{"key":"2026042913021612300_ocag029-B26","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1016\/j.jacc.2014.03.020","article-title":"ACC\/AHA\/SCAI 2014 health policy statement on structured reporting for the cardiac catheterization laboratory: a report of the American College of Cardiology Clinical Quality Committee","volume":"63","author":"Sanborn","year":"2014","journal-title":"J Am Coll Cardiol."},{"key":"2026042913021612300_ocag029-B27","author":"HL7 FHIR"}],"container-title":["Journal of the American Medical Informatics Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jamia\/advance-article-pdf\/doi\/10.1093\/jamia\/ocag029\/67280241\/ocag029.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jamia\/article-pdf\/33\/5\/1018\/67280241\/ocag029.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jamia\/article-pdf\/33\/5\/1018\/67280241\/ocag029.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:02:24Z","timestamp":1777482144000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jamia\/article\/33\/5\/1018\/8512190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,9]]},"references-count":27,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,3,9]]},"published-print":{"date-parts":[[2026,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jamia\/ocag029","relation":{},"ISSN":["1067-5027","1527-974X"],"issn-type":[{"value":"1067-5027","type":"print"},{"value":"1527-974X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,5]]},"published":{"date-parts":[[2026,3,9]]}}}