{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:46:39Z","timestamp":1791254799191,"version":"4.1.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD105939"],"award-info":[{"award-number":["R01HD105939"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The publication of the Phoenix criteria for pediatric sepsis and septic shock initiates a new era in clinical care and research of pediatric sepsis. Tools to consistently and accurately apply the Phoenix criteria to electronic health records (EHRs) is one part of building a robust and internally consistent body of research across multiple research groups and datasets.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>We developed the phoenix R package and Python module to provide researchers with intuitive and simple functions to apply the Phoenix criteria to EHR data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The phoenix R package and Python module enable researchers to apply the Phoenix criteria to EHR datasets and derive the relevant indicators, total scores, and sub-scores.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>The transition to the Phoenix criteria marks a major change in the conceptual definition of pediatric sepsis. Applicable across differentially resourced settings, the Phoenix criteria should help improve clinical care and research.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The phoenix R package and Python model are freely available on CRAN, PyPi, and GitHub. These tools enable the consistent and accurate application of the Phoenix criteria to EHR datasets.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jamiaopen\/ooae066","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:21:13Z","timestamp":1720138873000},"source":"Crossref","is-referenced-by-count":5,"title":["<tt>phoenix<\/tt>: an R package and Python module for calculating the Phoenix pediatric sepsis score and criteria"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6391-0795","authenticated-orcid":false,"given":"Peter E","family":"DeWitt","sequence":"first","affiliation":[{"name":"Department of Biomedical Informatics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, CO 80045, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth","family":"Russell","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, CO 80045, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret N","family":"Rebull","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, CO 80045, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L Nelson","family":"Sanchez-Pinto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics (Critical Care), Northwestern University Feinberg School of Medicine, and Ann and Robert H. Lurie Children\u2019s Hospital of Chicago , Chicago, IL 60611, United States"},{"name":"Department of Preventive Medicine (Health and Biomedical Informatics), Northwestern University Feinberg School of Medicine, and Ann and Robert H. Lurie Children\u2019s Hospital of Chicago , Chicago, IL 60611, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1483-4236","authenticated-orcid":false,"given":"Tellen D","family":"Bennett","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, CO 80045, United States"},{"name":"Section of Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, CO 80045, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"issue":"10219","key":"2024070500210597100_ooae066-B1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990\u20132017: analysis for the global burden of disease study","volume":"395","author":"Rudd","year":"2020","journal-title":"Lancet"},{"issue":"1","key":"2024070500210597100_ooae066-B2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/01.PCC.0000149131.72248.E6","article-title":"International Pediatric Sepsis Consensus Conference: definitions for sepsis and organ dysfunction in pediatrics","volume":"6","author":"Goldstein","year":"2005","journal-title":"Pediatr Crit Care Med"},{"issue":"8","key":"2024070500210597100_ooae066-B3","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1001\/jama.2024.0179","article-title":"International Consensus Criteria for pediatric sepsis and septic shock","volume":"331","author":"Schlapbach","year":"2024","journal-title":"JAMA"},{"issue":"8","key":"2024070500210597100_ooae066-B4","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1001\/jama.2024.0196","article-title":"Development and validation of the Phoenix criteria for pediatric sepsis and septic shock","volume":"331","author":"Sanchez-Pinto","year":"2024","journal-title":"JAMA"},{"issue":"8","key":"2024070500210597100_ooae066-B5","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/jama.2016.0288","article-title":"Assessment of clinical criteria for sepsis: for the Third International Consensus Definitions for sepsis and septic shock (sepsis-3)","volume":"315","author":"Seymour","year":"2016","journal-title":"JAMA"},{"issue":"8","key":"2024070500210597100_ooae066-B6","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for sepsis and septic shock (sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"issue":"8","key":"2024070500210597100_ooae066-B7","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1001\/jama.2023.27988","article-title":"Transitioning from SIRS to Phoenix with the updated pediatric sepsis criteria: the difficult task of simplifying the complex","volume":"331","author":"Jabornisky","year":"2024","journal-title":"JAMA"},{"issue":"1","key":"2024070500210597100_ooae066-B8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/s41597-022-01710-x","article-title":"Introducing the FAIR principles for research software","volume":"9","author":"Barker","year":"2022","journal-title":"Sci Data"}],"container-title":["JAMIA Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article-pdf\/7\/3\/ooae066\/58444789\/ooae066.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article-pdf\/7\/3\/ooae066\/58444789\/ooae066.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:21:18Z","timestamp":1720138878000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article\/doi\/10.1093\/jamiaopen\/ooae066\/7706304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jamiaopen\/ooae066","relation":{},"ISSN":["2574-2531"],"issn-type":[{"value":"2574-2531","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,10]]},"published":{"date-parts":[[2024,7,1]]},"article-number":"ooae066"}}