{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:59:14Z","timestamp":1791215954049,"version":"4.1.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This prospective single-arm trial assessed the use of an integrated patient platform (IPP) and effects on patient-reported outcomes survey (PROs) completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Head and neck, breast, and thoracic cancer patients undergoing radiotherapy (RT) were approached for registration for an IPP for PRO administration and integration of multiple health portals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-two patients were approached, 27 (38%) enrolled, and 18 used the IPP for PROs, 2 of which utilized integrative features. IPP user PRO completion rates were 100%, 89%, 89%, and 94% at baseline, end of RT, and 3- and 6-months post-RT, higher than the standard interface. Of the 45 who declined, 24 (53%) reported information security concerns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>While the IPP increased PRO completion, many declined enrollment, citing security concerns. Few utilized the portal\u2019s integrative features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IPPs show promise in aiding PRO completion; continued efforts to demonstrate data safety and utility of IPPs are merited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jamiaopen\/ooaf172","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T13:06:21Z","timestamp":1765285581000},"source":"Crossref","is-referenced-by-count":0,"title":["Patient-reported outcomes in radiotherapy (PRO-RT) utilizing an integrated patient portal; results from a prospective single-arm trial"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3269-3107","authenticated-orcid":false,"given":"Yasamin","family":"Sharifzadeh","sequence":"first","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S","family":"Harmsen","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Biostatistics and Health Sciences Research, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica F","family":"Burlile","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin F","family":"Pyfferoen","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C","family":"Amundson","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6017-8850","authenticated-orcid":false,"given":"Mark R","family":"Waddle","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2957-4687","authenticated-orcid":false,"given":"Daniel J","family":"Ma","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9522-014X","authenticated-orcid":false,"given":"Satomi","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Traci J","family":"Hammer","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia N","family":"Laack","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly S","family":"Corbin","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Radiation Oncology, , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"2026100511442762300_ooaf172-B1","doi-asserted-by":"publisher","first-page":"25","DOI":"10.37765\/ajmc.2022.88813","article-title":"Relationships between patient portal activation and patient satisfaction scores among CG-CAHPS and HCAHPS respondents","volume-title":"Am J Manag Care","author":"Naleef Fareed","year":"2022"},{"key":"2026100511442762300_ooaf172-B2","doi-asserted-by":"publisher","first-page":"e43086","DOI":"10.2196\/43086","article-title":"Patient-centered digital health records and their effects on health outcomes: systematic review","volume":"24","author":"Brands","year":"2022","journal-title":"J Med Internet Res"},{"key":"2026100511442762300_ooaf172-B3","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1089\/tmj.2022.0045","article-title":"Older adults\u2019 satisfaction with telemedicine during the COVID-19 pandemic: a systematic review","volume":"29","author":"Alsabeeha","year":"2023","journal-title":"Telemedicine e-Health"},{"key":"2026100511442762300_ooaf172-B4","doi-asserted-by":"publisher","first-page":"e8092","DOI":"10.2196\/medinform.8092","article-title":"Patient portal use and experience among older adults: systematic review","volume":"5","author":"Sakaguchi-Tang","year":"2017","journal-title":"JMIR Med Inform"},{"key":"2026100511442762300_ooaf172-B5","doi-asserted-by":"publisher","first-page":"e26189","DOI":"10.2196\/26189","article-title":"The impact of digital patient portals on health outcomes, system efficiency, and patient attitudes: updated systematic literature review","volume":"23","author":"Carini","year":"2021","journal-title":"J Med Internet Res"},{"key":"2026100511442762300_ooaf172-B6","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1200\/JCO.2013.53.5948","article-title":"What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials","volume":"32","author":"Kotronoulas","year":"2014","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B7","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s12955-022-01987-x","article-title":"Patient reported outcomes in oncology: changing perspectives\u2014a systematic review","volume":"20","author":"Silveira","year":"2022","journal-title":"Health Qual Life Outcomes"},{"key":"2026100511442762300_ooaf172-B8","doi-asserted-by":"publisher","first-page":"5470","DOI":"10.3390\/cancers14215470","article-title":"The effects of patient-reported outcome screening on the survival of people with cancer: a systematic review and meta-analysis","volume":"14","author":"Caminiti","year":"2022","journal-title":"Cancers (Basel)"},{"key":"2026100511442762300_ooaf172-B9","doi-asserted-by":"publisher","first-page":"e22549","DOI":"10.2196\/22549","article-title":"Patient portal use, perceptions of electronic health record value, and self-rated primary care quality among older adults: cross-sectional survey","volume":"23","author":"Cross","year":"2021","journal-title":"J Med Internet Res"},{"key":"2026100511442762300_ooaf172-B10","doi-asserted-by":"publisher","first-page":"e162","DOI":"10.1093\/jamia\/ocv114","article-title":"What do we know about developing patient portals? a systematic literature review","volume":"23","author":"Otte-Trojel","year":"2016","journal-title":"J Am Med Inf Assoc"},{"key":"2026100511442762300_ooaf172-B11","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.13063\/2327-9214.1262","article-title":"Patient portal as a tool for enhancing patient experience and improving quality of care in primary care practices","volume":"4","author":"Sorondo","year":"2017","journal-title":"EGEMS (Wash DC)"},{"key":"2026100511442762300_ooaf172-B12","doi-asserted-by":"publisher","first-page":"e41703","DOI":"10.7759\/cureus.41703","article-title":"A descriptive survey investigating the impact of the COVID-19 pandemic on the public\u2019s perception of healthcare professionals","volume":"15","author":"Stolzenberg","year":"2023","journal-title":"Cureus"},{"key":"2026100511442762300_ooaf172-B13","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1080\/17538157.2021.1879810","article-title":"Impact of patient access to their electronic health record: systematic review","volume":"46","author":"Tapuria","year":"2021","journal-title":"Inf Health Soc Care"},{"key":"2026100511442762300_ooaf172-B14","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1200\/JCO.2015.63.0830","article-title":"Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial","volume":"34","author":"Basch","year":"2016","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B15","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1001\/jama.2017.7156","article-title":"Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment","volume":"318","author":"Basch","year":"2017","journal-title":"JAMA"},{"key":"2026100511442762300_ooaf172-B16","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1093\/jnci\/djy181","article-title":"Blinding and patient-reported outcome completion rates in US food and drug administration cancer trial submissions, 2007\u20132017","volume":"111","author":"Roydhouse","year":"2019","journal-title":"JNCI J Natl Cancer Inst"},{"key":"2026100511442762300_ooaf172-B17","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.16_suppl.1579","article-title":"Completion rates and trends of the patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE) across 14 oncology clinical trials","volume":"41","author":"Hughes","year":"2023","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B18","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s11136-023-03505-y","article-title":"Patient adherence to patient-reported outcome measure (PROM) completion in clinical care: current understanding and future recommendations","volume":"33","author":"Unni","year":"2024","journal-title":"Qual Life Res"},{"key":"2026100511442762300_ooaf172-B19","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1200\/JCO.2022.40.28_suppl.141","article-title":"Patient-reported outcomes: completion, access, and equity","volume":"40","author":"McGuire","year":"2022","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B20","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.16_suppl.6609","article-title":"Assessment of patient reported outcomes (PROs) completion patterns in patients with cancer: examining real-world data","volume":"41","author":"Boakye","year":"2023","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B21","doi-asserted-by":"publisher","first-page":"djad225","DOI":"10.1093\/jnci\/djad225","article-title":"Disparities in electronic health record portal access and use among patients with cancer","volume":"116","author":"Griffin","year":"2023","journal-title":"JNCI J Natl Cancer Inst"},{"key":"2026100511442762300_ooaf172-B22","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1093\/jamia\/ocac227","article-title":"Disparities in patient portal access and the role of providers in encouraging access and use","volume":"30","author":"Richwine","year":"2023","journal-title":"J Am Med Inf Assoc"},{"key":"2026100511442762300_ooaf172-B23","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s12911-018-0644-4","article-title":"Patient portal adoption and use by hospitalized cancer patients: a retrospective study of its impact on adverse events, utilization, and patient satisfaction","volume":"18","author":"Aljabri","year":"2018","journal-title":"BMC Med Inform Decis Mak"},{"key":"2026100511442762300_ooaf172-B24","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1001\/jamaoncol.2017.5257","article-title":"Characteristics of patients using patient portals in oncology","volume":"4","author":"Pho","year":"2018","journal-title":"JAMA Oncol"},{"key":"2026100511442762300_ooaf172-B25","doi-asserted-by":"publisher","first-page":"e4847","DOI":"10.2196\/jmir.4847","article-title":"Barriers and facilitators to online portal use among patients and caregivers in a safety net health care system: a qualitative study","volume":"17","author":"Tieu","year":"2015","journal-title":"J Med Internet Res"},{"key":"2026100511442762300_ooaf172-B26","doi-asserted-by":"publisher","first-page":"105336","DOI":"10.1016\/j.ijmedinf.2023.105336","article-title":"Privacy concerns among the users of a national patient portal: a cross-sectional population survey study","volume":"183","author":"Kyyts\u00f6nen","year":"2024","journal-title":"Int J Med Inform"},{"key":"2026100511442762300_ooaf172-B27","doi-asserted-by":"publisher","first-page":"100171","DOI":"10.1016\/j.pecinn.2023.100171","article-title":"Patients\u2019 perspectives on digital health tools","volume":"2","author":"Madanian","year":"2023","journal-title":"Pec Innov"},{"key":"2026100511442762300_ooaf172-B28","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1038\/s41746-020-0265-z","article-title":"Aggregating multiple real-world data sources using a patient-centered health-data-sharing platform","volume":"3","author":"Dhruva","year":"2020","journal-title":"NPJ Digit Med"},{"key":"2026100511442762300_ooaf172-B29","doi-asserted-by":"publisher","first-page":"S51","DOI":"10.1016\/s0959-8049(05)80262-x","article-title":"Quality of life assessment in individuals with lung cancer: testing the lung cancer symptom scale (LCSS)","volume":"29A","author":"Hollen","year":"1993","journal-title":"Eur J Cancer"},{"key":"2026100511442762300_ooaf172-B30","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1200\/JCO.1999.17.3.1008","article-title":"Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35","volume":"17","author":"Bjordal","year":"1999","journal-title":"J Clin Oncol"},{"key":"2026100511442762300_ooaf172-B31","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1002\/jmrs.421","article-title":"A review of the barriers to using patient-reported outcomes (PROs) and patient-reported outcome measures (PROMs) in routine cancer care","volume":"68","author":"Nguyen","year":"2021","journal-title":"J Med Radiat Sci"},{"key":"2026100511442762300_ooaf172-B32","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-023-01559-z","article-title":"WHO declares end to COVID-19\u2019s emergency phase","author":"Lenharo","year":"2023","journal-title":"Nature"},{"key":"2026100511442762300_ooaf172-B33","doi-asserted-by":"publisher","first-page":"mzaa117","DOI":"10.1093\/intqhc\/mzaa117","article-title":"Healthcare cyber-attacks and the COVID-19 pandemic: an urgent threat to global health","volume":"33","author":"Muthuppalaniappan","year":"2021","journal-title":"Int J Quality Health Care"},{"key":"2026100511442762300_ooaf172-B34","author":"Murray-Watson","year":"2024"},{"key":"2026100511442762300_ooaf172-B35","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1186\/s12889-022-14399-9","article-title":"Examining the relationships between trust in providers and information, mistrust, and COVID-19 vaccine concerns, necessity, and intentions","volume":"22","author":"Williamson","year":"2022","journal-title":"BMC Public Health"},{"key":"2026100511442762300_ooaf172-B36","doi-asserted-by":"publisher","first-page":"e46044","DOI":"10.2196\/46044","article-title":"Adult patients\u2019 experiences of using a patient portal with a focus on perceived benefits and difficulties, and perceptions on privacy and security: qualitative descriptive study","volume":"10","author":"Son","year":"2023","journal-title":"JMIR Hum Factors"},{"key":"2026100511442762300_ooaf172-B37","doi-asserted-by":"publisher","first-page":"e18770","DOI":"10.7759\/cureus.18770","article-title":"Preferences towards electronically exchanging digital images with healthcare providers among US adults","volume":"13","author":"Wei","year":"2021","journal-title":"Cureus"},{"key":"2026100511442762300_ooaf172-B38","doi-asserted-by":"publisher","first-page":"e4255","DOI":"10.2196\/jmir.4255","article-title":"Patient portals and patient engagement: a state of the science review","volume":"17","author":"Irizarry","year":"2015","journal-title":"J Med Internet Res"}],"container-title":["JAMIA Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article-pdf\/9\/5\/ooaf172\/71604731\/ooaf172.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article-pdf\/9\/5\/ooaf172\/71604731\/ooaf172.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:44:32Z","timestamp":1791215072000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jamiaopen\/article\/doi\/10.1093\/jamiaopen\/ooaf172\/8865069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,9]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9,9]]}},"URL":"https:\/\/doi.org\/10.1093\/jamiaopen\/ooaf172","relation":{},"ISSN":["2574-2531"],"issn-type":[{"value":"2574-2531","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,9,9]]},"article-number":"ooaf172"}}