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Testing phases and quality control led to network-wide protocols ensuring consistency and accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>As the science of estimating disease risk evolves, standardized and high-throughput methods of collecting and manipulating complex data are required. Platforms should be open-source, modular, and reusable, ensuring flexibility, security, and integration across healthcare environments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The electronic MEdical Records and GEnomics (eMERGE) network successfully generated and returned comprehensive risk profiles using logic and data specific to 11 conditions in a secure and semi-automated fashion employing a customized REDCap database.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jamiaopen\/ooag118","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T17:53:05Z","timestamp":1783965185000},"source":"Crossref","is-referenced-by-count":0,"title":["Using a translational data platform to create clinical-grade genome-informed risk assessments"],"prefix":"10.1093","volume":"9","author":[{"given":"Jennifer L","family":"Morse","sequence":"first","affiliation":[{"name":"Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, TN 37232,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"He","sequence":"additional","affiliation":[{"name":"Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, TN 37232,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Bangash","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Mayo Clinic , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy K","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Boston Children\u2019s Hospital , Boston, MA 02115,","place":["United States"]},{"name":"Harvard Medical School , Boston, MA 02115,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Cortopassi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham , Birmingham, AL 35294,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Forman","sequence":"additional","affiliation":[{"name":"Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, TN 37232,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam S","family":"Gordon","sequence":"additional","affiliation":[{"name":"Center for Genetic Medicine, Northwestern University , Chicago, IL 60611,","place":["United 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