{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T11:27:11Z","timestamp":1764588431015,"version":"3.37.3"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Edible insects may contain arsenic. Analysis of arsenic species is necessary in order to accurately assess arsenic exposure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>An analytical method was validated and used to determine and quantitate arsenic species in edible insects.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Arsenic species were extracted from edible insects by heating at 100\u00b0C in 0.3\u2009mol\/L nitric acid. The concentration of arsenic species was then determined by LC\u2013inductively coupled plasma-mass spectrometry (LC\u2013ICP-MS) using an octadecylsilane (ODS) column with a mobile phase containing an ion-pair reagent.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The LOD (0.007\u20130.012\u2009mg\/kg), LOQ (0.021\u20130.038\u2009mg\/kg), repeatability (1.2\u20133.2%), intermediate precision (2.8\u20134.5%), and trueness (recoveries 97\u2013102% based on spiked samples) of the proposed method were satisfactory for inorganic arsenic, dimethylarsinic acid (DMA), and arsenobetaine (AB) in edible insects. Total arsenic was detected in all samples obtained in Japan (Asian forest scorpion, diving beetles, giant water bug, grasshoppers, June beetles, mole crickets, male rhino beetle, female rhino beetle, sago worms, and silkworm pupae) and consisted of mostly inorganic arsenic. Beetles in particular showed relatively high levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Arsenic content varies among edible insect species. Feed control is important, as arsenic concentrations in edible insects may be feed dependent.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Highlights<\/jats:title>\n                  <jats:p>Arsenic species in edible insects were analyzed by LC\u2013ICP-MS using an ODS column with a mobile phase containing an ion-pair reagent. Inorganic arsenic was detected in most samples, with concentrations ranging from &amp;lt;0.04 to 29.3\u2009mg\/kg.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jaoacint\/qsad083","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T14:55:34Z","timestamp":1689346534000},"page":"1525-1531","source":"Crossref","is-referenced-by-count":4,"title":["Determination of Arsenic Species in Edible Insects by LC\u2013ICP-MS"],"prefix":"10.1093","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8157-6859","authenticated-orcid":false,"given":"Eri","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Japan Food Research Laboratories , 6-11-10 Nagayama , Tama-shi, Tokyo 206-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1116-7240","authenticated-orcid":false,"given":"Makoto","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Japan Food Research Laboratories , 6-11-10 Nagayama , Tama-shi, Tokyo 206-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"year":"2013","author":"Food and Agriculture Organization of the United Nations (FAO), Forestry Paper 171","key":"2023110711251167200_qsad083-B1"},{"key":"2023110711251167200_qsad083-B2","doi-asserted-by":"publisher","first-page":"944","DOI":"10.3390\/insects13100944","volume":"13","author":"Ordo\u00f1ez-Araque","year":"2022","journal-title":"Insects"},{"key":"2023110711251167200_qsad083-B3","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1002\/fft2.167","volume":"3","author":"Giampieri","year":"2022","journal-title":"Food Front"},{"key":"2023110711251167200_qsad083-B4","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.4315\/JFP-21-099","volume":"84","author":"Kolakowski","year":"2021","journal-title":"J. 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