{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:51:32Z","timestamp":1791618692420,"version":"4.3.4"},"reference-count":59,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Two experiments were conducted to determine the effects of crude protein (CP) level in diets containing coarse wheat bran (CWB) with or without pharmacological levels of Zn (provided by zinc oxide: ZnO) on growth performance and fecal DM of nursery pigs. In experiment 1, 360 barrows (Line 200 \u00d7 400, DNA, Columbus, NE, initially 5.6 kg) were allotted to 1 of 6 dietary treatments from d 0 to 21 after weaning with 5 pigs per pen and 12 pens per treatment. Treatments included a positive control diet (21% CP) with 3,000 mg\/kg Zn in phase 1 and 2,000 mg\/kg in phase 2; negative control (21% CP) with 110 mg\/kg added Zn, and 4 diets containing 4% CWB and 110 mg\/kg added Zn formulated to contain 21%, 19.5%, 18%, or 16.5% CP. The 2 control diets and 21% CP CWB diet contained 1.40% standardized ileal digestible (SID) Lys in phase 1 and 1.35% SID Lys in phase 2, while the 19.5%, 18%, and 16.5% CP diets contained 1.33, 1.25 and 1.20% Lys, respectively, in both phases. Pigs fed the positive control diet containing pharmacological ZnO had increased (P &amp;lt; 0.05) ADG and G:F compared with the negative control and the 21% CP CWB diet. Reducing CP (concurrently with SID Lys) in diets containing CWB decreased ADG and G:F (linear, P = 0.002); however, fecal DM increased (linear, P = 0.005). In experiment 2, two groups of 300 and 350 pigs, initially 7.0 and 6.2 kg, respectively, were used with 5 pigs per pen and 26 pens per treatment. The objective was to determine if adding back essential AA would improve growth performance of pigs fed the low CP diets. All dietary treatments were fed for 13 days, contained 4% CWB, and consisted of: (1) positive control with 2,000 mg\/kg of Zn and 21% CP (1.35% SID Lys); (2) no ZnO and 21% CP; and 3 diets with no ZnO formulated to 18% CP and (3) 1.2% SID Lys; (4) 1.35% SID Lys by the addition of feed grade amino acids (AA), and (5) diet 4 with non-essential amino acids (NEAA; Gly and Glu). Pigs fed 21% CP with ZnO had increased (P = 0.001) ADG compared to those fed 18% CP (1.35% SID Lys) with high levels of feed grade amino acids or those fed the reduced SID Lys (1.2%) diet. Overall, G:F was improved (P &amp;lt; 0.001) for pigs fed 21% CP diets and those fed the 18% CP diet with NEAA compared to pigs fed 1.2% SID Lys and pigs fed high levels of feed grade amino acids. Fecal DM was increased for pigs fed the reduced SID Lys diet. In summary, pharmacological levels of Zn improve pig growth performance, but reducing CP (and subsequently SID Lys) decreased nursery pig growth performance.<\/jats:p>","DOI":"10.1093\/jas\/skab090","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T11:31:45Z","timestamp":1616499105000},"source":"Crossref","is-referenced-by-count":26,"title":["Effects of feeding diets containing low crude protein and coarse wheat bran as alternatives to zinc oxide in nursery pig diets"],"prefix":"10.1093","volume":"99","author":[{"given":"Kelsey L","family":"Batson","sequence":"first","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilda I","family":"Calder\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Statistics, College of Arts and Sciences, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike D","family":"Tokach","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C","family":"Woodworth","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D","family":"Goodband","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-0729","authenticated-orcid":false,"given":"Steve S","family":"Dritz","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Medicine\/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-0201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M","family":"DeRouchey","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,23]]},"reference":[{"key":"2021081104105347100_CIT0001","volume-title":"Method for determining acid detergent fiber, ANKOM 200\/220 fiber analyzer","author":"ANKOM Technology.","year":"1998"},{"key":"2021081104105347100_CIT0002","volume-title":"Method for determining crude fiber, ANKOM 2000 fiber analyzer","author":"ANKOM Technology.","year":"2005"},{"key":"2021081104105347100_CIT0003","volume-title":"Method for determining neutral detergent fiber, ANKOM 2000 fiber analyzer","author":"ANKOM Technology.","year":"2017"},{"key":"2021081104105347100_CIT0004","volume-title":"Official methods of analysis of AOAC International","author":"AOAC International.","year":"2019","edition":"21"},{"issue":"11","key":"2021081104105347100_CIT0005","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1002\/jsfa.3324","article-title":"Food and feed components for gut health-promoting adhesion of E. coli and Salmonella enterica","volume":"88","author":"Becker","year":"2008","journal-title":"J. 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