{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T10:54:58Z","timestamp":1782384898035,"version":"3.54.5"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","award":["2016YFD0501201"],"award-info":[{"award-number":["2016YFD0501201"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Hunan Natural Science Foundation","award":["2021JJ20045"],"award-info":[{"award-number":["2021JJ20045"]}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2018QNRC001"],"award-info":[{"award-number":["2018QNRC001"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2020NK2013"],"award-info":[{"award-number":["2020NK2013"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2020GK4095"],"award-info":[{"award-number":["2020GK4095"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2021AB200663"],"award-info":[{"award-number":["2021AB200663"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019081","name":"Science and Technology Program of Hunan Province","doi-asserted-by":"publisher","award":["2020NK2013"],"award-info":[{"award-number":["2020NK2013"]}],"id":[{"id":"10.13039\/501100019081","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019081","name":"Science and Technology Program of Hunan Province","doi-asserted-by":"publisher","award":["2020GK4095"],"award-info":[{"award-number":["2020GK4095"]}],"id":[{"id":"10.13039\/501100019081","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Key R&D Program of Guangxi Province","award":["2021AB200663"],"award-info":[{"award-number":["2021AB200663"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The iron status of sows has a great influence on reproductive performance. Iron deficiency reduces reproductive performance and newborn piglet survival rate of sow. The hemoglobin is a potential predictor for the iron status of sows and is convenient for rapid detection in pig farms. However, the relationship between iron status, hemoglobin, placental trace elements, and reproductive performance remains unclear. In this study, the hemoglobin and reproductive performance of more than 500 sows with first to sixth parities at different gestation stages (25, 55, 75, 95, and 110 d of gestation) in two large-scale sow farms were collected, and the content of placental Fe, Zn, Mn, and Cu was analyzed. The results show that hemoglobin levels of sows during pregnancy (days 75, 95, and 110) decreased significantly (P\u2005&amp;lt;\u20050.001). As the parity increases, the hemoglobin levels of sows at days 25 and 55 of gestation and placental mineral element contents including Fe, Zn, Mn, and Cu at delivery decreased (P\u2005&amp;lt;\u20050.05), while the litter size, birth alive, and litter weights increased gradually (P\u2005&amp;lt;\u20050.001). Furthermore, hemoglobin during pregnancy had a negative linear correlation with litter weight and average weight (P\u2005&amp;lt;\u20050.05), and higher hemoglobin at day 25 of gestation may reduce the number of stillbirths (P\u2005=\u20050.05), but higher hemoglobin at day 110 of gestation may tend to be a benefit for the birth (P\u2005=\u20050.01). And there was a significant positive linear correlation between hemoglobin at day 110 of gestation and placental Fe and Mn levels (P\u2005=\u20050.002, P\u2005=\u20050.013). There was also a significant positive linear correlation among Fe, Zn, Mn, and Cu in the placenta (P\u2005&amp;lt;\u20050.001). The levels of Fe, Zn, and Mn in the placental at delivery were positively related to the average weight of the fetus (P\u2005=\u20050.048, P\u2005=\u20050.027, P\u2005=\u20050.047), and placental Cu was linearly correlated with litter size (P\u2005=\u20050.029). Our research revealed that the requirements for iron during gestation were varied in different gestation periods and parities. The feeds should be adjusted according to the gestation periods, parities, or iron status to meet the iron requirements of sows and fetal pigs.<\/jats:p>","DOI":"10.1093\/jas\/skac010","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T01:01:22Z","timestamp":1642035682000},"source":"Crossref","is-referenced-by-count":9,"title":["Correlations of gestational hemoglobin level, placental trace elements content, and reproductive performances in pregnant sows"],"prefix":"10.1093","volume":"100","author":[{"given":"Liu","family":"Guo","sequence":"first","affiliation":[{"name":"Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125, China"},{"name":"University of Chinese Academy of Sciences, Beijing 101408, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongming","family":"Zhang","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Tang","sequence":"additional","affiliation":[{"name":"Animal Breeding and Genetics Key Laboratory of Sichuan Province, Livestock and Poultry Biological Products Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, Chengdu, Sichuan 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglin","family":"Dong","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Changsha Xinjia Bio-Engineering Co., Ltd., Changsha, Hunan 410000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangchu","family":"Wang","sequence":"additional","affiliation":[{"name":"Changsha Xinjia Bio-Engineering Co., Ltd., Changsha, Hunan 410000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Yin","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125, China"},{"name":"University of Chinese Academy of Sciences, Beijing 101408, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Wan","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"key":"2022022708492960100_CIT0001","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13028-019-0496-7","article-title":"Association between sow and piglet blood hemoglobin concentrations and stillbirth risk.","volume":"61","author":"Bhattarai","year":"2019","journal-title":"Acta Vet. 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