{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T10:59:12Z","timestamp":1780397952374,"version":"3.54.1"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Neonates with intrauterine growth retardation (IUGR) are prone to suffer from delayed postnatal growth and development during the early stages of life. Ferulic acid (FA) is a phenolic compound that is abundantly present in fruits and vegetables and has various health benefits. Hence, we explored whether FA supplementation could favorably affect the growth performance, antioxidant capacity, and intestinal development of piglets with IUGR. In total, eight normal-birth-weight (NBW) piglets and 16 piglets with IUGR (age, 7 d) were assigned to be fed either basic formula milk (NBW and IUGR groups, respectively) or basic formula milk supplemented with 100 mg\/kg FA (IUGR + FA group) for 21 d. At necropsy, the serum and intestinal tissues were collected. FA supplementation increased (P &amp;lt; 0.05) the feed conversion ratio and serum total superoxide dismutase and catalase activities in piglets with IUGR. Moreover, FA supplementation elevated (P &amp;lt; 0.05) the duodenal lactase and maltase activities, jejunal villus height and jejunal maltase activity but reduced (P &amp;lt; 0.05) the duodenal crypt depth and duodenal and jejunal cell apoptosis, cleaved cysteinyl aspartic acid protease-3 (caspase-3) content and cleaved caspase-9 content in piglets with IUGR. In summary, FA supplementation could elevate antioxidant capacity and facilitate intestinal development, thus resulting in increased feed efficiency in piglets with IUGR.<\/jats:p>","DOI":"10.1093\/jas\/skac144","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T18:02:12Z","timestamp":1650391332000},"source":"Crossref","is-referenced-by-count":12,"title":["Effects of ferulic acid on the growth performance, antioxidant capacity, and intestinal development of piglets with intrauterine growth retardation"],"prefix":"10.1093","volume":"100","author":[{"given":"Jin","family":"Wan","sequence":"first","affiliation":[{"name":"International Institute of Food Innovation, Nanchang University, Nanchang 330200, Jiangxi, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqiu","family":"Luo","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, Sichuan, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Ruan","sequence":"additional","affiliation":[{"name":"International Institute of Food Innovation, Nanchang University, Nanchang 330200, Jiangxi, People\u2019s Republic of China"},{"name":"College of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,4,19]]},"reference":[{"key":"2022051715321406900_CIT0001","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3389\/fnut.2019.00121","article-title":"Anti-hypertensive effect of cereal antioxidant ferulic acid and its mechanism of action","volume":"6","author":"Alam","year":"2019","journal-title":"Front. 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