{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T23:48:34Z","timestamp":1778975314608,"version":"3.51.4"},"reference-count":55,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Minks are seasonal breeders whose seminiferous epithelium undergoes regression through massive germ cell death, leaving only Sertoli cells and spermatogonial cells in the tubules. However, the molecular mechanisms that control this biological process remain largely unknown. This study describes a transcriptomic analysis of mink testes at various reproductive stages (active, regressing, and inactive). A comparison of seminiferous epithelium at different stages of reproduction shows that cell adhesion is altered during regression. In addition, genes and proteins involved in forming the blood\u2013testis barrier (BTB) were examined in sexually active and inactive minks. The seminiferous epithelium in the testes of sexually inactive minks expressed occludin, but this expression was not discernibly observed in the testes of sexually active minks. There was no discernible expression of CX43 in the seminiferous epithelium in the testes of sexually inactive minks, but CX43 was expressed in the testes of sexually active minks. During the regression process, we observed a remarkable increase in the expression levels of Claudin-11, which is associated with Sertoli-germ cell junctions. In conclusion, these findings suggest a loss of Sertoli-germ cell adhesion, which may regulate postmeiotic cell shedding during testicular regression in mink.<\/jats:p>","DOI":"10.1093\/jas\/skad190","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:22:03Z","timestamp":1686183723000},"source":"Crossref","is-referenced-by-count":3,"title":["Cell adhesion function was altered during the seasonal regression of the seminiferous epithelium in the mink species <i>Neovison vison<\/i>"],"prefix":"10.1093","volume":"101","author":[{"given":"Yufei","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Inner Mongolia Agricultural University , Zhao Wu Da Road No. 306, Hohhot 010018 , China"},{"name":"Inner Mongolia Key Laboratory of Basic Veterinary Science , Hohhot 010018 , China"},{"name":"Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture , Hohhot 010018 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6770-6372","authenticated-orcid":false,"given":"Yanzhu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences , Changchun , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodong","family":"Cao","sequence":"additional","affiliation":[{"name":"School of pharmacy, Inner Mongolia Medical University , Hohhot, Inner Mongolia Autonmous Region , China"},{"name":"School of pharmacy New Drug Safety Evaluation Research Center, Inner Mongolia Medical University , Hohhot, Inner Mongolia Autonmous Region , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanhua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Agriculture and Animal Husbandry Comprehensive Inspection and Testing Center of chifeng , Inner Mongolia , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuying","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Inner Mongolia Agricultural University , Zhao Wu Da Road No. 306, Hohhot 010018 , China"},{"name":"Inner Mongolia Key Laboratory of Basic Veterinary Science , Hohhot 010018 , China"},{"name":"Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture , Hohhot 010018 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"2023061718152272800_CIT0001","doi-asserted-by":"crossref","first-page":"636","DOI":"10.3382\/ps\/pev342","article-title":"Effects of season on the reproductive organ and plasma testosterone concentrations in guinea cocks (Numida meleagris)","volume":"95","author":"Abdul","year":"2016","journal-title":"Poult. 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