{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:20:24Z","timestamp":1783938024932,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"vor","delay-in-days":246,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Physicochemical characteristics of dietary fibers may modulate digesta transit behavior. The present study was conducted to clarify the effect of level and particle size (PS) of insoluble fibers on digesta mean retention time (MRT) in the proximal gastrointestinal tract (mouth-ileocecal junction). Six ileal-cannulated pigs (26.8\u2005\u00b1\u20052.08 kg) were assigned to 3 dietary treatments in a 3\u2005\u00d7\u20053 replicated Latin-square design. Finely ground (1 mm screen) or coarse (intact) oat husks (OH) and soybean hulls (SBH) were added (50:50, w\/w) to a maize\u2013whey protein\u2013wheat-based diet at 50 (low) or 250 g\/kg (high) inclusion levels to obtain a low-fine fiber (LF), high-fine fiber (HF), and high-coarse fiber (HC) diet. Markers to follow liquids (Co-EDTA), fine solids (Y3O2), or fibrous particles (Yb-mordanted OH and Cr-mordanted SBH) were given as a single pulse dose and marker concentrations were subsequently measured hourly in digesta for 13 h after administration. Mean retention time values were obtained from the concentration of markers in digesta observed over time by fitting a generalized Michaelis\u2013Menten equation and calculating the time of peak. Fiber addition and fiber particle size neither affected the MRT of liquid nor solid digesta phases (P\u2005=\u20050.903). Segregation between solid and liquid digesta phases was observed for all diets (P\u2005&amp;lt;\u20050.0001), although the extent of segregation was greater for LF compared with HF and HC (P\u2005=\u20050.0220). The MRT of SBH particles, but not of OH-particles was longer for coarse vs fine PS (96 min, P\u2005&amp;lt;\u20050.05). In conclusion, digesta MRT was influenced by the dietary concentration but not by PS of insoluble fibers. The addition of insoluble fibers reduces digesta phase segregation from mouth to distal ileum in growing pigs.<\/jats:p>","DOI":"10.1093\/jas\/skad299","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T21:14:24Z","timestamp":1693862064000},"source":"Crossref","is-referenced-by-count":14,"title":["Insoluble fibers affect digesta transit behavior in the upper gastrointestinal tract of growing pigs, regardless of particle size"],"prefix":"10.1093","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9220-6318","authenticated-orcid":false,"given":"Sebastian","family":"Dorado-Montenegro","sequence":"first","affiliation":[{"name":"Animal Nutrition Group, Wageningen University & Research , Wageningen, Gelderland, 6700 AH , The Netherlands"},{"name":"Escuela de Zootecnia, Universidad de Costa Rica , San Jos\u00e9 2060 , Costa Rica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Lammers-Jannink","sequence":"additional","affiliation":[{"name":"Animal Nutrition Group, Wageningen University & Research , Wageningen, Gelderland , 6700 AH , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0494-9259","authenticated-orcid":false,"given":"Walter","family":"Gerrits","sequence":"additional","affiliation":[{"name":"Animal Nutrition Group, Wageningen University & Research , Wageningen, Gelderland , 6700 AH , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3842-8411","authenticated-orcid":false,"given":"Sonja","family":"de Vries","sequence":"additional","affiliation":[{"name":"Animal Nutrition Group, Wageningen University & Research , Wageningen, Gelderland , 6700 AH , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,4]]},"reference":[{"key":"2023111707241585600_CIT0001","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/J.ENG.2017.03.010","article-title":"Nutritional and metabolic consequences of feeding high-fiber diets to swine: a review","volume":"3","author":"Agyekum","year":"2017","journal-title":"Engineering"},{"key":"2023111707241585600_CIT0002","article-title":"Method of determining and expressing fineness of feed materials by sieving, S319.4","volume-title":"American Society of Agricultural and Biological Engineers","author":"ASABE","year":"2008"},{"key":"2023111707241585600_CIT0003","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0377-8401(97)00009-6","article-title":"Carbohydrate and lignin contents of plant materials used in animal feeding","volume":"67","author":"Bach Knudsen","year":"1997","journal-title":"Anim. Feed Sci. Technol"},{"key":"2023111707241585600_CIT0004","doi-asserted-by":"crossref","first-page":"14930","DOI":"10.1073\/pnas.94.26.14930","article-title":"Slow and fast dietary proteins differently modulate postprandial protein accretion","volume":"94","author":"Boirie","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2023111707241585600_CIT0005","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1002\/jsfa.6160","article-title":"Gastric emptying rate and chyme characteristics for cooked brown and white rice meals in vivo","volume":"93","author":"Bornhorst","year":"2013","journal-title":"J. Sci. Food Agric"},{"key":"2023111707241585600_CIT0006","doi-asserted-by":"crossref","first-page":"E1383","DOI":"10.1111\/1750-3841.12228","article-title":"Particle size distribution of brown and white rice during gastric digestion measured by image analysis","volume":"78","author":"Bornhorst","year":"2013","journal-title":"J. Food Sci"},{"key":"2023111707241585600_CIT0007","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1080\/10408398.2016.1180501","article-title":"The behavior of dietary fiber in the gastrointestinal tract determines its physiological effect","volume":"57","author":"Capuano","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr"},{"key":"2023111707241585600_CIT0008","volume-title":"Feed table 2018. Chemical composition and nutritional values of feedstuffs","author":"CVB","year":"2018"},{"key":"2023111707241585600_CIT0009","first-page":"275","article-title":"The use of tracers or markers in digestion studies","volume-title":"Feed evaluation science","author":"de Vries","year":"2018"},{"key":"2023111707241585600_CIT0010","volume-title":"Energy requirement for maintenance in growing pigs. (CVB-Documentation report; No. nr. 57)","author":"Everts","year":"2015"},{"key":"2023111707241585600_CIT0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jas\/skab020","article-title":"ASAS-NANP symposium: digestion kinetics in pigs: the next step in feed evaluation and a ready-to-use modeling exercise","volume":"99","author":"Gerrits","year":"2021","journal-title":"J. Anim. Sci"},{"key":"2023111707241585600_CIT0012","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1079\/BJN2000271","article-title":"Changes in intragastric meal distribution are better predictors of gastric emptying rate in conscious pigs than are meal viscosity or dietary fibre concentration","volume":"85","author":"Guerin","year":"2001","journal-title":"Br. J. Nutr"},{"key":"2023111707241585600_CIT0013","doi-asserted-by":"crossref","first-page":"5314","DOI":"10.2527\/jas.2013-6328","article-title":"Effect of insoluble-low fermentable fiber from corn-ethanol distillation origin on energy, fiber, and amino acid digestibility, hindgut degradability of fiber, and growth performance of pigs","volume":"91","author":"Gutierrez","year":"2013","journal-title":"J. Anim. Sci"},{"key":"2023111707241585600_CIT0014","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1093\/jn\/nxaa210","article-title":"Determination of true ileal amino acid digestibility in the growing pig for calculation of digestible indispensable amino acid score (DIAAS)","volume":"150","author":"Hodgkinson","year":"2020","journal-title":"J. Nutr"},{"key":"2023111707241585600_CIT0015","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/gut.23.4.292","article-title":"Gastric emptying of solids in man","volume":"23","author":"Holt","year":"1982","journal-title":"Gut"},{"key":"2023111707241585600_CIT0016","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.foodchem.2015.01.117","article-title":"Study of hydration properties of wheat bran as a function of particle size","volume":"179","author":"Jacobs","year":"2015","journal-title":"Food Chem"},{"key":"2023111707241585600_CIT0017","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s11483-009-9116-9","article-title":"Modes of disintegration of solid foods in simulated gastric environment","volume":"4","author":"Kong","year":"2009","journal-title":"Food Biophys"},{"key":"2023111707241585600_CIT0018","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00360-008-0264-x","article-title":"Physical characteristics of digesta and their influence on flow and mixing in the mammalian intestine: A review","volume":"178","author":"Lentle","year":"2008","journal-title":"J. Comp. Physiol. B"},{"key":"2023111707241585600_CIT0019","first-page":"253","article-title":"A note on the rate of passage of digesta in pigs ileo-rectostomized or fitted with an ileal T-cannula","volume":"53","author":"Leterme","year":"1991","journal-title":"Anim Prod"},{"key":"2023111707241585600_CIT0020","doi-asserted-by":"crossref","first-page":"114347","DOI":"10.1016\/j.anifeedsci.2019.114347","article-title":"Size reduction in feed technology and methods for determining, expressing and predicting particle size: A review","volume":"261","author":"Lyu","year":"2020","journal-title":"Anim. Feed Sci. Technol"},{"key":"2023111707241585600_CIT0021","doi-asserted-by":"crossref","first-page":"G844","DOI":"10.1152\/ajpgi.2001.280.5.G844","article-title":"Assessment of antral grinding of a model solid meal with echo-planar imaging","volume":"280","author":"Marciani","year":"2001","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"2023111707241585600_CIT0022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40104-018-0303-8","article-title":"Amylopectin structure and crystallinity explains variation in digestion kinetics of starches across botanic sources in an in vitro pig model","volume":"9","author":"Martens","year":"2018","journal-title":"J. Anim. Sci. Biotechnol"},{"key":"2023111707241585600_CIT0023","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1017\/S0007114519002198","article-title":"Whole digesta properties as influenced by feed processing explain variation in gastrointestinal transit times in pigs","volume":"122","author":"Martens","year":"2019","journal-title":"Br. J. Nut"},{"key":"2023111707241585600_CIT0024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0007114519000849","article-title":"Transglycosylated starch accelerated intestinal transit and enhanced bacterial fermentation in the large intestine using a pig model","volume":"122","author":"Metzler-Zebeli","year":"2019","journal-title":"Br. J. Nutr"},{"key":"2023111707241585600_CIT0025","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3390\/nu10030275","article-title":"Gastrointestinal transit time, glucose homeostasis and metabolic health: Modulation by dietary fibers","volume":"10","author":"M\u00fcller","year":"2018","journal-title":"Nutrients"},{"key":"2023111707241585600_CIT0026","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.1039\/D0FO02917C","article-title":"Tracking physical breakdown of rice-and wheat-based foods with varying structures during gastric digestion and its influence on gastric emptying in a growing pig model","volume":"12","author":"Nadia","year":"2021","journal-title":"Food Funct"},{"key":"2023111707241585600_CIT0027","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.2527\/jas1986.6341140x","article-title":"Markers for estimating digesta flow in pigs and the effects of dietary fiber","volume":"63","author":"Pond","year":"1986","journal-title":"J. Anim. Sci"},{"key":"2023111707241585600_CIT0028","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.1007\/s00394-021-02567-3","article-title":"Interplay between grain digestion and fibre in relation to gastro-small-intestinal passage rate and feed intake in pigs","volume":"60","author":"Ratanpaul","year":"2021","journal-title":"Eur. J. Nutr"},{"key":"2023111707241585600_CIT0029","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.livsci.2010.06.027","article-title":"Role of dietary fibre source and meal size on the ileal transit of digesta in growing pigs","volume":"133","author":"Sol\u00e0-Oriol","year":"2010","journal-title":"Livest. Sci"},{"key":"2023111707241585600_CIT0030","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/jsfa.3433","article-title":"Water-holding capacity of insoluble fibre decreases free water and elevates digesta viscosity in the rat","volume":"89","author":"Takahashi","year":"2009","journal-title":"J. Sci. Food Agric"},{"key":"2023111707241585600_CIT0031","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1039\/C9FO00485H","article-title":"Physical effects of dietary fibre on simulated luminal flow, studied by in vitro dynamic gastrointestinal digestion and fermentation","volume":"10","author":"Tamargo","year":"2019","journal-title":"Food Funct"},{"key":"2023111707241585600_CIT0032","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/jsfa.2740310702","article-title":"Investigation of chromium, cerium and cobalt as markers in digesta. Rate of passage studies","volume":"31","author":"Ud\u00e9n","year":"1980","journal-title":"J. Sci. Food Agric"},{"key":"2023111707241585600_CIT0033","first-page":"81","article-title":"Accurate determination of titanium as titanium dioxide for limited sample size digestibility studies of feed and food matrices by Inductively Coupled Plasma Optical Emission Spectroscopy with real-time simultaneous internal standardization","volume":"31","author":"van Bussel","year":"2010","journal-title":"At. Spectrosc"},{"key":"2023111707241585600_CIT0034","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1093\/jn\/137.10.2234","article-title":"Body fat deposition does not originate from carbohydrates in milk-fed calves","volume":"137","author":"van den Borne","year":"2007","journal-title":"J. Nutr"},{"key":"2023111707241585600_CIT0035","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2174\/157340106775472001","article-title":"An animal model to study digesta passage in different compartments of the gastro-intestinal tract (GIT) as affected by dietary composition","volume":"2","author":"van Leeuwen","year":"2006","journal-title":"Curr. Nutr. Food Sci"},{"key":"2023111707241585600_CIT0036","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1136\/gut.37.2.216","article-title":"Effect of bran particle size on gastric emptying and small bowel transit in humans: A scintigraphic study","volume":"37","author":"Vincent","year":"1995","journal-title":"Gut"},{"key":"2023111707241585600_CIT0037","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.aninu.2022.08.012","article-title":"Diets enriched with finely ground wheat bran alter digesta passage rate and composition of the gut microbiome in sows","volume":"12","author":"Wang","year":"2023","journal-title":"Anim. Nutr"},{"key":"2023111707241585600_CIT0038","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1017\/S0007114507682981","article-title":"Digesta transit in different segments of the gastrointestinal tract of pigs as affected by insoluble fibre supplied by wheat bran","volume":"98","author":"Wilfart","year":"2007","journal-title":"Br. J. Nutr"},{"key":"2023111707241585600_CIT0039","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1017\/S002185960001546X","article-title":"The determination of chromic oxide in faeces samples by atomic absorption spectrophotometry","volume":"59","author":"Williams","year":"1962","journal-title":"J. Agric. Sci"},{"key":"2023111707241585600_CIT0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2049-1891-4-17","article-title":"The effects of dietary fiber level on nutrient digestibility in growing pigs","volume":"4","author":"Zhang","year":"2013","journal-title":"J. Anim. Sci. Biotechnol"},{"key":"2023111707241585600_CIT0041","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2527\/jas.53718","article-title":"Starch and fiber properties affect their kinetics of digestion and thereby digestive physiology in pigs","volume":"90","author":"Zijlstra","year":"2012","journal-title":"J. Anim. Sci"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jas\/advance-article-pdf\/doi\/10.1093\/jas\/skad299\/51346896\/skad299.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skad299\/53478585\/skad299.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skad299\/53478585\/skad299.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T13:25:06Z","timestamp":1700227506000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/doi\/10.1093\/jas\/skad299\/7259835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,1]]},"references-count":41,"URL":"https:\/\/doi.org\/10.1093\/jas\/skad299","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,1,1]]},"published":{"date-parts":[[2023,1,1]]},"article-number":"skad299"}}