{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:02:03Z","timestamp":1787320923922,"version":"build-2736575974"},"reference-count":37,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aimed to evaluate the effects of early weaning (EW) on body composition, hormone concentrations and metabolites, and reproductive performance of Nelore cows in the subsequent breeding season (BS). Suckled cows that became pregnant by timed-AI (TAI) in the 2020-BS were exposed in 2021 to early weaning at 150 d (27 primiparous [PRI] and 74 multiparous [MUL]) or conventional weaning (CW) at 240 d postpartum (30 PRI and 77 MUL). Body weight (BW) and body condition score (BCS) were determined at 2020-BS, EW, CW, prepartum, and 2021-BS. Blood samples were collected at EW, CW, prepartum (54.75\u2005\u00b1\u20050.56 d prepartum), and 2021-TAI and assayed for insulin-like growth factor-1 (IGF-I), non-esterified fatty acid (NEFA), and \u03b2-hydroxybutyrate (BHB) concentrations. In 2021-BS, cows were exposed to a P4\/E2-based protocol for TAI at day 0 (D0), and a second TAI was performed at D22 in females detected with luteolysis (D20) by Doppler ultrasound. The presence of corpus luteum (CL) on D10, estrous expression, and dominant follicle (DF) diameter, and blood perfusion (BP) on D2 and D0 were determined. Data were analyzed by ANOVA or logistic regression of SAS as a 2\u2005\u00d7\u20052 factorial with main factors of parity (PRI or MUL) and weaning strategy (EW or CW). An interaction of parity and weaning strategy was not observed (P\u2005&amp;gt;\u20050.1), but the weight (kg) and BCS were greater (P\u2005&amp;lt;\u20050.05) in MUL cows at the five timepoints, and EW cows were heavier than CW at the moment of CW (541 vs. 493 kg; and 5.3 vs. 4.3), prepartum (551 vs. 506 kg; and 5.2 vs. 4.4) and 2021-BS (475 vs. 450 kg; and 4.5 vs. 3.7). Plasma urea concentration at 2021-BS was greater (P\u2005=\u20050.01) for PRI than for MUL. A parity-by-time interaction was observed (P\u2005\u2264\u20050.05) for concentrations of IGF-I, NEFA, and BHB. PRI cows had greater (P\u2005\u2264\u20050.05) concentrations of IGF-I at EW and greater (P\u2005\u2264\u20050.05) prepartum concentrations of NEFA and BHB than MUL cows. The proportion of cows with CL at D10 was not affected (P\u2005&amp;gt;\u20050.1) by weaning but was greater (P\u2005&amp;lt;\u20050.05) in MUL than in PRI cows (40.4 vs. 15.7%). The diameter of DF and proportion of BP on D0 were greater (P\u2005&amp;lt;\u20050.05) in EW cows than in CW cows. The pregnancy rate (P\/AI, %) at the first TAI was greater (P\u2005&amp;lt;\u20050.05) in EW cows (60% vs. 45%), whereas no difference (P\u2005&amp;gt;\u20050.1) was observed at the second TAI. Cumulative P\/AI (first and second TAIs) was greater (P\u2005&amp;lt;\u20050.05) in EW cows (81% vs. 63%). In conclusion, weaning at 150 d in Nelore cattle is a strategy to successfully recover the parous cow\u2019s body condition and to improve pregnancy success in the next BS, regardless of the cow\u2019s parity order.<\/jats:p>","DOI":"10.1093\/jas\/skad330","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T16:45:05Z","timestamp":1696005905000},"source":"Crossref","is-referenced-by-count":13,"title":["Effects of early weaning on the reproductive performance of suckled Nelore cows in the subsequent breeding season"],"prefix":"10.1093","volume":"101","author":[{"given":"Thiago Kan","family":"Nishimura","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda Guimar\u00e3es","family":"da Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Abitante","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4556-4315","authenticated-orcid":false,"given":"Carl Robertson","family":"Dahlen","sequence":"additional","affiliation":[{"name":"North Dakota State University, Department of Animal Science, Center for Nutrition and Pregnancy, NDSU Department 7630 , Fargo, ND 58108-6050 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4961-3866","authenticated-orcid":false,"given":"Rodrigo Silva","family":"Goulart","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germ\u00e1n Dar\u00edo Ram\u00edrez","family":"Zamudio","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0849-9948","authenticated-orcid":false,"given":"Saulo","family":"Luz Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Henrique de Almeida","family":"Santana","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlindo","family":"Saran Netto","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Roberto","family":"Leme","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Pugliesi","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo, 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,1]]},"reference":[{"key":"2023111317471910000_CIT0001","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.anireprosci.2004.05.006","article-title":"Pre-pubertal and postpartum anestrus in tropical Zebu cattle","volume":"82-83","author":"Abeygunawardena","year":"2004","journal-title":"Anim. 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