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Nano-composite of copper and carbon (NCCC), a novel copper donor with stronger antibacterial properties, is expected to promote broiler growth and diminish the negative effects of excess copper (Cu). Hence, the purpose of this study is to investigate the effects of NCCC on growth performance, immunity, and antioxidant ability of yellow-feathered broilers. A total of 240 1-d-old male yellow-feathered broilers were selected and randomly divided into four groups, with five replications per group and 12 birds per replication. The CON group was fed corn-soybean basal diets, while the N50, N100, and N200 groups were supplemented with 50, 100, and 200 mg\/kg of NCCC in basal diets, respectively. The trial lasted for 63 d. The results demonstrated that only 200 mg\/kg NCCC addition significantly increased the Cu content in serum and feces, and liver Cu content linearly increased with NCCC dosage increment (P\u2005&amp;lt;\u20050.05). Meanwhile, NCCC supplementation did not alter the growth performance, slaughter performance, immune organ indexes, and liver antioxidant ability of broilers (P\u2005&amp;gt;\u20050.05), but optimized the serum cytokine pattern by elevating the level of serum IL-10 (P\u2005&amp;lt;\u20050.05), and there were linear and quadratic increases in serum IL-4 with NCCC dosage increment (P\u2005&amp;lt;\u20050.05). On the whole, in spite of no impact on growth performance, 50 mg\/kg NCCC was optimal to supplement in chicken diets due to the rise of serum IL-10 level and no extra environmental pollution and tissue residues.<\/jats:p>","DOI":"10.1093\/jas\/skad362","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T08:13:26Z","timestamp":1698653606000},"source":"Crossref","is-referenced-by-count":4,"title":["Dietary supplementation with nano-composite of copper and carbon on growth performance, immunity, and antioxidant ability of yellow-feathered broilers"],"prefix":"10.1093","volume":"101","author":[{"given":"Jing","family":"Liu","sequence":"first","affiliation":[{"name":"Institute , Fuzhou 350013 , China"},{"name":"of Animal , Fuzhou 350013 , China"},{"name":"Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences , Fuzhou 350013 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiying","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqin","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingjie","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zitao","family":"Fan","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changkang","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingcheng","family":"Ye","sequence":"additional","affiliation":[{"name":"Institute , Fuzhou 350013 , China"},{"name":"of Animal , Fuzhou 350013 , China"},{"name":"Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences , Fuzhou 350013 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-4083","authenticated-orcid":false,"given":"Pingting","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Animal Science (College of Bee Science), Fujian Agriculture and Forestry University , Fuzhou 350002 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"2023110800054346000_CIT0001","doi-asserted-by":"crossref","first-page":"536","DOI":"10.3390\/ani9080536","article-title":"Use of licorice (Glycyrrhiza glabra) herb as a feed additive in poultry: current knowledge and prospects","volume":"9","author":"Alagawany","year":"2019","journal-title":"Animals (Basel)"},{"key":"2023110800054346000_CIT0002","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.14202\/vetworld.2021.1371-1379","article-title":"Performance of Swarnadhara breeder hens supplemented with reduced levels of different copper forms","volume":"14","author":"Aminullah","year":"2021","journal-title":"Vet. 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