{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:39:36Z","timestamp":1785886776708,"version":"3.56.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We aimed to evaluate the effects of early weaning on the productive and reproductive characteristics of Nelore heifer progeny. Ninety-five calves from primiparous (PRI) and multiparous (MUL) dams were assigned to one of two weaning strategies; 1) early weaning at 150 d (149\u2005\u00b1\u20051.97) of age (EW; n\u2005=\u200516 from PRI and 31 from MUL); or 2) conventional weaning at 240 d (247\u2005\u00b1\u20052.41) of age (CW; 16 from PRI and 32 from MUL). All heifers received ~5 g\/kg of body weight (BW) of creep-feed as fed from 90 d of age until weaning. After weaning, each group of heifers was transferred to a Brachiaria spp. paddock and received 5 g\/kg of BW of a protein-energy supplement until 12 mo of age. Then, heifers were confined and fed a diet with a ratio of 79:31 (corn silage: concentrate) for 4 mo, during which they were submitted to a hormonal protocol to induce puberty and timed artificial insemination (TAI). Reproductive tract score (RTS, 1 to 5 scale: 1 being infantile and 5 being cyclic) and endometrial thickness were determined at 12 mo of age, rump fat thickness (RFT), and BW every 28\u2005\u00b1\u20054 d through the breeding season, and plasma concentrations of IGF-I were evaluated at 12, 14, and 16 mo. At 15.6 mo of age heifers were submitted to a P4\/E2 protocol for TAI at day 0 (D0), and a second TAI was performed at D22 in nonpregnant heifers. Ultrasound was used to determine the presence of corpus luteum on D10 and dominant follicle (DF) diameter and blood perfusion on D2 and D0. Data were analyzed using SAS by ANOVA or logistic regression. Though heifers from EW were lighter (P\u2005&amp;lt;\u20050.05) than CW at postweaning time points and CW presented a greater (P\u2005=\u20050.002) RFT than EW heifers from 11 to 15 mo, weaning strategy did not affect (P\u2005&amp;gt;\u20050.1) body condition score at TAI. Concentrations of IGF-I did not differ (P\u2005&amp;gt;\u20050.1) between heifers weaned at 150 and 240 d. The proportion of pubertal heifers, endometrium tone and thickness, and RTS at 16 mo did not differ (P\u2005&amp;gt;\u20050.1) between EW and CW groups. The diameter of DF on D2 and D0 and follicular blood perfusion on D0 were greater (P\u2005&amp;lt;\u20050.05) for heifers in the CW group than EW group, but P\/AI at first and second TAI did not differ (P\u2005&amp;gt;\u20050.1) between groups. In conclusion, early weaning in Nelore heifers moderately reduces postweaning growth but does not affect puberty and reproductive performance before the breeding season when submitted to confinement.<\/jats:p>","DOI":"10.1093\/jas\/skad379","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T14:20:33Z","timestamp":1700230833000},"source":"Crossref","is-referenced-by-count":5,"title":["Effects of early weaning on productive and reproductive performance of Nelore heifers"],"prefix":"10.1093","volume":"101","author":[{"given":"Thiago Kan","family":"Nishimura","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4961-3866","authenticated-orcid":false,"given":"Rodrigo Silva","family":"Goulart","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germ\u00e1n Dar\u00edo","family":"Ram\u00edrez-Zamudio","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda Guimar\u00e3es","family":"da Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus Sousa","family":"de Paula Carlis","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Abitante","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0849-9948","authenticated-orcid":false,"given":"Saulo Luz","family":"Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4556-4315","authenticated-orcid":false,"given":"Carl Robertson","family":"Dahlen","sequence":"additional","affiliation":[{"name":"North Dakota State University, Department of Animal Science, Center for Nutrition and Pregnancy, NDSU Department 7630 , Fargo, ND 58108-6050 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlindo","family":"Saran Netto","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Roberto","family":"Leme","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Science, School of Animal Science and Food Engineering , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Pugliesi","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science , Pirassununga, S\u00e3o Paulo 13635-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,18]]},"reference":[{"key":"2023121323290205000_CIT0001","first-page":"19","article-title":"The use of reproductive tract scoring in beef heifers","volume":"12","author":"Anderson","year":"1991","journal-title":"Agric. 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