{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:05:08Z","timestamp":1753877108233,"version":"3.41.2"},"reference-count":65,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"vor","delay-in-days":103,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This study evaluated the effect of dietary calcium (Ca) levels and deoxynivalenol (DON) contamination on Ca and phosphorus (P) utilization and bone mineralization in piglets. During an initial 13-d depletion phase, 64 piglets (15.7\u2005\u00b1\u20050.7\u00a0kg) received a control (DON\u2212) or DON-contaminated treatment (DON+, 2.7\u00a0mg DON\/kg) with either a low Ca (Ca\u2212, 0.39%) or normal Ca level (Ca+, 0.65%) with a constant digestible P level (0.40%). A second group of 16 piglets received DON\u2212 or DON+ treatments for 9 d for gene expression analysis. During the subsequent 14-d repletion phase, all piglets were fed a Ca+ DON\u2212 diet containing 0.65% Ca and 0.35% digestible P without DON. After 5 d of the depletion phase, the absorption of P (DON\u2005\u00d7\u2005Ca; P\u2005&amp;lt;\u20050.05) and Ca was increased by the Ca\u2212 (P\u2005&amp;lt;\u20050.01) and DON+ (P\u2005&amp;lt;\u20050.01) diet. After 13 d, feed conversion ratio (P\u2005&amp;lt;\u20050.01) and average daily feed intake (P\u2005=\u20050.06) tended to decrease with the Ca\u2212 diet. The bone mineral content (BMC) gain was decreased by Ca, especially with Ca\u2212 DON\u2005+\u2005(DON\u2005\u00d7\u2005Ca, P\u2005&amp;lt;\u20050.05). The P absorption was increased by Ca\u2212 DON\u2005+\u2005(DON\u2005\u00d7\u2005Ca, P\u2005&amp;lt;\u20050.01), although the P retention efficiency was only increased by Ca+ DON\u2005+\u2005(DON\u2005\u00d7\u2005Ca, P\u2005&amp;lt;\u20050.001). The absorption of Ca was increased by DON+ (P\u2005&amp;lt;\u20050.001), and the Ca efficiency was increased by Ca\u2212 DON\u2212 (DON\u2005\u00d7\u2005Ca, P\u2005&amp;lt;\u20050.01). After 9 d, the gene expression of intestinal claudin 12 (P\u2005&amp;lt;\u20050.01) and CYP24A1 (P\u2005&amp;lt;\u20050.05), femur cortical RANKL (P\u2005&amp;lt;\u20050.05) and OPG (P\u2005=\u20050.06), and renal calbindin D9K (P\u2005&amp;lt;\u20050.05) and Klotho (P\u2005=\u20050.07) were decreased by DON+. The Ca (P\u2005=\u20050.06) and magnesium (P\u2005&amp;lt;\u20050.01) concentrations were decreased by DON+, and the Ca (P\u2005=\u20050.06) and P digestibility (P\u2005&amp;lt;\u20050.01) were increased. After the repletion phase, Ca\u2212 piglets recovered their BMC deficit, but not those receiving DON+ (DON\u2005\u00d7\u2005Ca; P\u2005=\u20050.06). The Ca (P\u2005&amp;lt;\u20050.05) and P (P\u2005=\u20050.06) retention efficiency tended to increase with Ca\u2212. The absorption of Ca and P was increased by Ca\u2212 and DON+ (DON\u2005\u00d7\u2005Ca, P\u2005&amp;lt;\u20050.05). The results show that piglets increased their Ca and P utilization efficiency, allowing them to recover the BMC deficit caused by Ca\u2212, but not when the piglets were exposed to DON. Pigs previously receiving Ca-deficient diet with DON still have lower body Ca and P, leading to elevated calcitriol concentrations and enhanced Ca and P intestinal absorption. The fact that DON decreased the expression of genes implicated in Ca intestinal and renal transport and P excretion after 9 d can potentially explain the reduced plasma Ca concentration.<\/jats:p>","DOI":"10.1093\/jas\/skae099","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T15:54:22Z","timestamp":1712937262000},"source":"Crossref","is-referenced-by-count":1,"title":["Impact of deoxynivalenol in a calcium depletion and repletion nutritional strategy in piglets"],"prefix":"10.1093","volume":"102","author":[{"given":"B\u00e9atrice","family":"Sauv\u00e9","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, Universit\u00e9 Laval , Qu\u00e9bec (QC) , Canada G1V 0A6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Guay","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Universit\u00e9 Laval , Qu\u00e9bec (QC) , Canada G1V 0A6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Pierre","family":"L\u00e9tourneau Montminy","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Universit\u00e9 Laval , Qu\u00e9bec (QC) , Canada G1V 0A6"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"key":"2024042909213177900_CIT0001","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.2527\/jas.2005-355","article-title":"Ingestion of low doses of deoxynivalenol does not affect hematological, biochemical, or immune responses of piglets","volume":"84","author":"Accensi","year":"2006","journal-title":"J. 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Anim. Sci"},{"key":"2024042909213177900_CIT0039","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.2527\/jas.2014-8519","article-title":"Modeling the metabolic fate of dietary phosphorus and calcium and the dynamics of body ash content in growing pigs","volume":"93","author":"Letourneau-Montminy","year":"2015","journal-title":"J. Anim. Sci"},{"key":"2024042909213177900_CIT0040","doi-asserted-by":"crossref","first-page":"3914","DOI":"10.2527\/jas.2013-7320","article-title":"Apparent total tract digestibility of dietary calcium and phosphorus and their efficiency in bone mineral retention are affected by body mineral status in growing pigs","volume":"92","author":"Le\u0301tourneau-Montminy","year":"2014","journal-title":"J. Anim. 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Suppl"},{"key":"2024042909213177900_CIT0058","first-page":"26","article-title":"The effect of the trichothecene mycotoxin deoxynivalenol (vomitoxin) on calcium homeostasis, vitamin D metabolism and receptors in rats","volume":"36","author":"Sergeev","year":"1990","journal-title":"Vopr Med Khimii"},{"key":"2024042909213177900_CIT0059","doi-asserted-by":"crossref","first-page":"5209","DOI":"10.1093\/jas\/sky378","article-title":"An acute challenge with a deoxynivalenol-contaminated diet has short- and long-term effects on performance and feeding behavior in finishing pigs","volume":"96","author":"Serviento","year":"2018","journal-title":"J. Anim. Sci"},{"key":"2024042909213177900_CIT0060","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2478\/v10102-010-0019-x","article-title":"Deoxynivalenol and its toxicity","volume":"3","author":"Sobrova","year":"2010","journal-title":"Interdiscip. 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