{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T02:12:44Z","timestamp":1771035164064,"version":"3.50.1"},"reference-count":53,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We investigated the effects of a calf starter supplemented with calcium salts of medium-chain fatty acids (MCFA-Ca) on growth and plasma hormone concentration in calves. Twelve Holstein calves were randomly assigned to two dietary groups (without supplementation [CON] and supplemented with MCFA-Ca [MCFA]) from 4 d of age. Calves were fed 1.0\u00a0kg\/d of milk replacer until 5\u00a0wk of age and were completely weaned at 7\u00a0wk of age. Calves in the MCFA group received a calf starter containing 1% MCFA-Ca. dry matter intake (DMI) was measured daily, and body weight was measured weekly. Rumen fluid was collected at 13\u00a0wk of age to measure pH and volatile fatty acid concentration. Preprandial blood samples were collected weekly to measure the basal plasma hormone and metabolite concentrations. At 4, 8, and 13\u00a0wk of age, peri-prandial blood samples were collected every 30\u00a0min, from 60\u00a0min before feeding to 120\u00a0min after feeding, to observe metabolic responses to feeding. In addition, insulin sensitivity was assessed using euglycemic-hyperinsulinemic clamps at 4, 8, and 13\u00a0wk of age in three calves from each treatment. There were no differences in starter and hay DMI between the treatments. However, the average daily gain (ADG) after weaning was higher in the MCFA group than in the CON group. Weekly changes in plasma parameters did not differ between the treatments. Plasma concentrations of preprandial ghrelin and postprandial total ketone bodies at 13\u00a0wk of age were higher in the MCFA group than in the CON group. At 8\u00a0wk of age, peri-prandial plasma insulin concentrations were lower in the MCFA group than in the CON group. There were no differences between the treatments in terms of insulin sensitivity. The present study suggested that feeding weaning calves MCFA-Ca increases the ADG during the postweaning period, which may be mediated by endocrine signals, such as enhanced ghrelin secretion and decreased insulin secretion, without altering insulin sensitivity.<\/jats:p>","DOI":"10.1093\/jas\/skae166","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T16:09:53Z","timestamp":1718381393000},"source":"Crossref","is-referenced-by-count":3,"title":["Effect of feeding calf starter with calcium salts of medium-chain fatty acids on the growth and metabolic hormones in calves"],"prefix":"10.1093","volume":"102","author":[{"given":"Y","family":"Masuda","sequence":"first","affiliation":[{"name":"Department of Agriculture, University Farm, Utsunomiya University , Mohka, 321 - 4415 , Japan"},{"name":"United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology , Fuchu, 183 - 8538 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6047-8709","authenticated-orcid":false,"given":"R","family":"Fukumori","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, Rakuno Gakuen University , Ebetsu, 069-8501 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Tomoshige","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University Farm, Utsunomiya University , Mohka, 321 - 4415 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Sarentonglaga","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University Farm, Utsunomiya University , Mohka, 321 - 4415 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Sugino","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life, Hiroshima University , Higashi-Hiroshima, 739-8528 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Nagao","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University Farm, Utsunomiya University , Mohka, 321 - 4415 , Japan"},{"name":"United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology , Fuchu, 183 - 8538 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"2024070313391225200_CIT0001","doi-asserted-by":"crossref","first-page":"8087","DOI":"10.3168\/jds.2022-22065","article-title":"Effects of mixing a high-fat extruded pellet with a dairy calf starter on performance, feed intake, and digestibility","volume":"105","author":"Amado","year":"2022","journal-title":"J. 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