{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:39:39Z","timestamp":1782837579298,"version":"3.54.5"},"reference-count":34,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A total of 360 pigs (DNA 600\u2005\u00d7\u2005241; initially 5.8\u00a0kg) were used in a 45-d growth study to evaluate the effects of adding 25(OH)D3 with 3 levels of standardized total tract digestible (STTD) P on nursery pig growth performance, bone and urine characteristics, and serum vitamin D. Pigs were weaned at 19 d of age and randomly allotted to 1 of 6 dietary treatments with 5 pigs per pen and 12 replications per treatment. Dietary treatments were arranged in a 2\u2005\u00d7\u20053 factorial with main effects of 25(OH)D3 (0 or 50 \u00b5g\/kg equivalent to 2,000 IU\/kg of vitamin D3; Hy-D, dsm-firmenich, Plainsboro, NJ) and STTD P (70%, 100%, or 130% of the NRC [NRC 2012. Nutrient requirements of swine. 11th rev. ed. Natl. Acad. Press, Washington, DC) requirement estimate on a dietary percentage basis]. All diets contained 1,653 IU\/kg of vitamin D3. On day 45, 1 pig per pen was euthanized to collect the right fibula, metacarpal, and 2nd and 10th ribs. Overall, increasing STTD P increased (quadratic, P\u2005\u2264\u20050.003) ADG, ADFI, and G:F with minimal improvement above 100% of the NRC STTD P requirement estimate. Added 25(OH)D3 had no effect on growth performance. Increasing STTD P decreased urinary Ca concentration (linear, P\u2005&amp;lt;\u20050.001) and increased urinary P concentration (quadratic, P\u2005&amp;lt;\u20050.001). When pigs were fed added 25(OH)D3, serum 25(OH)D3 increased (quadratic, P\u2005=\u20050.005) as STTD P increased but no differences were observed when 25(OH)D3 was not added and STTD P increased (25(OH)D3 \u00d7 STTD P interaction, P\u2005=\u20050.032). When pigs were fed 25(OH)D3, serum 1,25(OH)2D3 increased (quadratic, P\u2005&amp;lt;\u20050.001) as STTD P decreased but the increase was not significant when no 25(OH)D3 was fed (STTD P\u2005\u00d7\u200525(OH)D3 interaction, P\u2005=\u20050.002). Bone ash percentage and weight increased (quadratic, P\u2005\u2264\u20050.065) in all bones as STTD P increased. Added 25(OH)D3 had no effect on bone density or bone ash weight; however, the reduction in bone ash percentage observed with reducing STTD P level tended to be less when 25(OH)D3 was provided (linear interaction, P\u2005=\u20050.098). Increasing STTD P decreased the likelihood of abnormal histologic bone lesions in the 10th rib. In summary, added 25(OH)D3 had limited effect on growth performance; however, an increase in serum concentrations of 25(OH)D3 and 24,25(OH)2D3 was observed. The addition of 25(OH)D3 to P-deficient diets increased percentage bone ash. Increasing STTD P to 100% of NRC [NRC 2012. Nutrient requirements of swine. 11th rev. ed. Natl. Acad. Press, Washington, DC] requirement estimate increased growth and 130% of NRC maximized bone ash.<\/jats:p>","DOI":"10.1093\/jas\/skae254","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T14:19:02Z","timestamp":1724854742000},"source":"Crossref","is-referenced-by-count":3,"title":["Effects of added 25(OH)D3 with varying standardized total tract digestible phosphorus concentrations on nursery pig performance, bone characteristics, and serum vitamin D status"],"prefix":"10.1093","volume":"102","author":[{"given":"Larissa L","family":"Becker","sequence":"first","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6144-6714","authenticated-orcid":false,"given":"Jordan T","family":"Gebhardt","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Medicine\/Pathobiology, College of Veterinary Medicine, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike D","family":"Tokach","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7268-4278","authenticated-orcid":false,"given":"Jason C","family":"Woodworth","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D","family":"Goodband","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M","family":"DeRouchey","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University , Manhattan, KS 66506-0201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon R","family":"Bergstrom","sequence":"additional","affiliation":[{"name":"dsm-firmenich , Plainsboro, NJ 08536-1908 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L","family":"Siepker","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University , Ames, IA 50011 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"key":"2024092911212022000_CIT0001","volume-title":"Official methods of analysis AOAC International","author":"AOAC","year":"2006","edition":"18th ed"},{"key":"2024092911212022000_CIT0002","doi-asserted-by":"crossref","first-page":"28","DOI":"10.54846\/jshap\/862","article-title":"Survey of serum vitamin D status across stages of swine production and evaluation of supplemental bulk vitamin D premixes used in swine diets","volume":"23","author":"Arnold","year":"2015","journal-title":"J. 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