{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T23:31:17Z","timestamp":1787959877465,"version":"build-2784847793"},"reference-count":75,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Our aim was to investigate the effects of maternal (F0) body weight (BW) gain during the first 84 d of gestation on body composition, ovarian reserve, and hormonal and metabolic parameters of breeding-age F1 heifers, as well as the BW and morphometry of F2 fetuses. The study also evaluated the effect of maternal BW gain (F0) on the mRNA relative abundance of the small intestine of both F1 heifers and F2 fetuses. Crossbred Angus heifers (F0; n\u2005=\u2005100) were managed to gain 0.20\u00a0kg\/d (low gain [LG], n\u2005=\u200550) or 0.75\u00a0kg\/d (moderate gain [MG], n\u2005=\u200550) for the first 84 d of gestation. Subsequently, F0 dams were managed on a common forage-based diet for the rest of gestation until the weaning of the F1 offspring. At 15 mo of age, a subset of F1 heifers was randomly selected for the current experiment (n\u2005=\u20058 LG and n\u2005=\u20058 MG). Heifers were bred via artificial insemination (AI; day 0), then harvested on day 84 of gestation. On days \u221210, 42, and 84, BW was recorded, and blood was collected and analyzed for concentrations of glucose, non-esterified fatty acids, progesterone, insulin, and insulin-like growth factor-1. The weight of F1 carcasses, organs, gravid uteri, and F2 fetuses and organs were recorded at harvest. Visible follicles were counted on F1 ovaries at harvest, and histology was used to count microscopic follicles. Liver and jejunal samples from F1 heifers were collected to measure tissue oxygen consumption and jejunal samples from F1 heifers and F2 fetuses were collected for mRNA relative abundance analysis. BW of F1 heifers from MG dams tended to be 12\u00a0kg greater (P\u2005=\u20050.06) than for F1 heifers from LG dams. Concentrations of glucose were greater (P\u2005=\u20050.03) in F1 heifers from the MG group, with no differences in other blood metabolites or follicular populations (P\u2005\u2265\u20050.16). Interestingly, mammary glands were heavier (P\u2005=\u20050.05), and placentas and body depth tended to be heavier and greater, respectively (P\u2005\u2264\u20050.10), for F2 fetuses from F0 LG heifers. Oxygen consumption in the liver and jejunum, as well as mRNA relative abundance in the jejunum of F1 heifers, were not affected by F0 rate of gain (P\u2005\u2265\u20050.16). However, the NDUFC1, SDHA, UQCR1, and PPARG genes were upregulated (P\u2005\u2264\u20050.05) in the jejunum of F2 fetuses from the LG group. In conclusion, BW gain of F0 heifers during early gestation exerts subtle effects on pre-breeding BW and blood metabolites in F1 offspring, with impacts present in F2 placenta, mammary gland, and intestine.<\/jats:p>","DOI":"10.1093\/jas\/skae295","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T12:07:26Z","timestamp":1727352446000},"source":"Crossref","is-referenced-by-count":7,"title":["Rate of body weight gain during early gestation in F0 beef heifers has effects that extend multigenerationally to the F2 fetuses"],"prefix":"10.1093","volume":"102","author":[{"given":"Friederike","family":"Baumgaertner","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germ\u00e1n Dar\u00edo","family":"Ram\u00edrez-Zamudio","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]},{"name":"Department of Animal Science, School of Animal Science and Food Engineering, University of S\u00e3o Paulo , Pirassununga, SP 13635-900 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Clara B","family":"Menezes","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella M","family":"Jurgens","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara R","family":"Hirchert","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L","family":"Hurlbert","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerri A","family":"Bochantin-Winders","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1082-5535","authenticated-orcid":false,"given":"Wellison J S","family":"Diniz","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Auburn University , Auburn, AL 36849 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence P","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison K","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel P","family":"Borowicz","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S R","family":"Underdahl","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D","family":"Kirsch","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheri T","family":"Dorsam","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin K","family":"Sedivec","sequence":"additional","affiliation":[{"name":"Central Grasslands Research Extension Center, North Dakota State University , Streeter, ND 58483 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5694-4778","authenticated-orcid":false,"given":"Kendall C","family":"Swanson","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel S","family":"Caton","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4556-4315","authenticated-orcid":false,"given":"Carl R","family":"Dahlen","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University , Fargo, ND 58108 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,26]]},"reference":[{"key":"2024102510191879300_CIT0001","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1007\/s00335-016-9631-1","article-title":"Transgenerational effects of maternal diet on metabolic and reproductive ageing","volume":"27","author":"Aiken","year":"2016","journal-title":"Mamm. Genome"},{"key":"2024102510191879300_CIT0002","doi-asserted-by":"crossref","first-page":"771832","DOI":"10.3389\/fmicb.2021.771832","article-title":"Characterization of the microbiota associated with 12-week-old bovine fetuses exposed to divergent in utero nutrition","volume":"12","author":"Amat","year":"2022","journal-title":"Front. Microbiol"},{"key":"2024102510191879300_CIT0003","doi-asserted-by":"crossref","first-page":"E55","DOI":"10.3168\/jds.S0022-0302(04)70061-2","article-title":"Rumen development, intestinal growth and hepatic metabolism in the pre- and postweaning ruminant","volume":"87","author":"Baldwin","year":"2004","journal-title":"J. Dairy Sci"},{"key":"2024102510191879300_CIT0004","doi-asserted-by":"crossref","first-page":"skae193","DOI":"10.1093\/jas\/skae193","article-title":"Effects of rate of body weight gain during the first trimester of gestation on beef heifer and offspring performance, hormones and metabolites, and response to vaccination","volume":"102","author":"Baumgaertner","year":"2024","journal-title":"J. Anim. Sci."},{"key":"2024102510191879300_CIT0005","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1079\/NRR200239","article-title":"Regulation of placental nutrient transport and implications for fetal growth","volume":"15","author":"Bell","year":"2002","journal-title":"Nutr. Res. Rev"},{"key":"2024102510191879300_CIT0006","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s13364-017-0337-x","article-title":"Seasonal variations of the digestive tract of the Eurasian beaver Castor fiber","volume":"63","author":"Be\u0142\u017cecki","year":"2018","journal-title":"Mammal Res"},{"key":"2024102510191879300_CIT0007","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.2527\/1992.7041137x","article-title":"Level of nutrition and visceral organ protein synthetic capacity and nucleic acid content in sheep","volume":"70","author":"Burrin","year":"1992","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0008","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.2527\/jas.2014-7713","article-title":"Use of a stair-step compensatory gain nutritional regimen to program the onset of puberty in beef heifers","volume":"92","author":"Cardoso","year":"2014","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0009","doi-asserted-by":"crossref","first-page":"skaa358","DOI":"10.1093\/jas\/skaa358","article-title":"Maternal periconceptual nutrition, early pregnancy, and developmental outcomes in beef cattle","volume":"98","author":"Caton","year":"2020","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0010","first-page":"1","article-title":"Intra-uterine programming of future fertility","volume":"00","author":"Chavatte-Palmer","year":"2023","journal-title":"Reprod. Domest. Anim"},{"key":"2024102510191879300_CIT0011","doi-asserted-by":"crossref","first-page":"101095","DOI":"10.1016\/j.mam.2022.101095","article-title":"The placental exposome, placental epigenetic adaptations and lifelong cardio-metabolic health","volume":"87","author":"Cleal","year":"2022","journal-title":"Mol. Aspects Med"},{"key":"2024102510191879300_CIT0012","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.2527\/jas2017.1983","article-title":"Maternal nutrition and stage of early pregnancy in beef heifers: Impacts on expression of glucose, fructose, and cationic amino acid transporters in utero-placental tissues","volume":"95","author":"Crouse","year":"2017","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0013","doi-asserted-by":"crossref","first-page":"696","DOI":"10.3390\/metabo12080696","article-title":"Vitamin and mineral supplementation and rate of weight gain during the first trimester of gestation in beef heifers alters the fetal liver amino acid, carbohydrate, and energy profile at day 83 of gestation","volume":"12","author":"Crouse","year":"2022","journal-title":"Metabolites"},{"key":"2024102510191879300_CIT0014","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1095\/biolreprod60.2.349","article-title":"Superovulatory response of one ovary is related to the micro- and macroscopic population of follicles in the contralateral ovary of the cow","volume":"60","author":"Cushman","year":"1999","journal-title":"Biol. Reprod"},{"key":"2024102510191879300_CIT0015","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.2527\/jas.2008-1728","article-title":"Evaluation of antral follicle count and ovarian morphology in crossbred beef cows: Investigation of influence of stage of the estrous cycle, age, and birth weight","volume":"87","author":"Cushman","year":"2009","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0016","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.livsci.2014.01.033","article-title":"The impact of cow nutrient status during the second and third trimesters on age at puberty, antral follicle count, and fertility of daughters","volume":"162","author":"Cushman","year":"2014","journal-title":"Livest. Sci"},{"key":"2024102510191879300_CIT0017","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s00125-013-2869-1","article-title":"Insulin signalling mechanisms for triacylglycerol storage","volume":"56","author":"Czech","year":"2013","journal-title":"Diabetologia"},{"key":"2024102510191879300_CIT0018","doi-asserted-by":"crossref","first-page":"11668","DOI":"10.3390\/ijms222111668","article-title":"Programming of embryonic development","volume":"22","author":"Dahlen","year":"2021","journal-title":"Int. J. Mol. Sci"},{"key":"2024102510191879300_CIT0019","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3390\/genes12030385","article-title":"Maternal vitamin and mineral supplementation and rate of maternal weight gain affects placental expression of energy metabolism and transport-related genes","volume":"12","author":"Diniz","year":"2021","journal-title":"Genes"},{"key":"2024102510191879300_CIT0020","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3390\/ani13040600","article-title":"Periconceptual maternal nutrition affects fetal liver programming of energy- and lipid-related genes","volume":"13","author":"Diniz","year":"2023","journal-title":"Animals"},{"key":"2024102510191879300_CIT0021","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.5713\/ajas.18.0428","article-title":"Current situation and future trends for beef production in the united states of America \u2014 a review","volume":"31","author":"Drouillard","year":"2018","journal-title":"Asian-Australas. J. Anim. Sci"},{"key":"2024102510191879300_CIT0022","doi-asserted-by":"crossref","first-page":"3846","DOI":"10.2527\/jas.2014-7568","article-title":"Maternal overnutrition enhances mRNA expression of adipogenic markers and collagen deposition in skeletal muscle of beef cattle fetuses","volume":"92","author":"Duarte","year":"2014","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0023","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1079\/BJN19860140","article-title":"Effect of previous nutrition on body composition and maintenance energy costs of growing lambs. Brit","volume":"56","author":"Ferrell","year":"1986","journal-title":"J. Nutr"},{"key":"2024102510191879300_CIT0024","doi-asserted-by":"crossref","first-page":"e0112111","DOI":"10.1371\/journal.pone.0112111","article-title":"Achieving body weight adjustments for feeding status and pregnant or non-pregnant condition in beef cows","volume":"10","author":"Gionbelli","year":"2015","journal-title":"PLoS One"},{"key":"2024102510191879300_CIT0025","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/jpn.12572","article-title":"Intestinal development of bovine foetuses during gestation is affected by foetal sex and maternal nutrition","volume":"101","author":"Gionbelli","year":"2017","journal-title":"J. Anim. Physiol. Anim. Nutr"},{"key":"2024102510191879300_CIT0026","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/jpn.12786","article-title":"Foetal development of skeletal muscle in bovines as a function of maternal nutrition, foetal sex and gestational age","volume":"102","author":"Gionbelli","year":"2018","journal-title":"Anim. Physiol. Anim. Nutr"},{"key":"2024102510191879300_CIT0027","doi-asserted-by":"crossref","first-page":"4668","DOI":"10.2527\/jas2017.1713","article-title":"The effects of maternal nutrition on the messenger ribonucleic acid expression of neutral and acidic amino acid transporters in bovine uteroplacental tissues from day sixteen to fifty of gestation","volume":"95","author":"Greseth","year":"2017","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0028","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.siny.2008.09.004","article-title":"Normal and abnormal maternal metabolism during pregnancy","volume":"14","author":"Hadden","year":"2009","journal-title":"Semin. Fetal. Neonatal. Med"},{"key":"2024102510191879300_CIT0029","doi-asserted-by":"crossref","first-page":"F1","DOI":"10.1530\/REP-22-0453","article-title":"DOHaD: a menagerie of adaptations and perspectives: large animal models of developmental programming: sustenance, stress, and sex matter","volume":"165","author":"Hammer","year":"2023","journal-title":"Reproduction"},{"key":"2024102510191879300_CIT0030","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.domaniend.2014.05.002","article-title":"Poor maternal nutrition during gestation in sheep reduces circulating concentrations of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in offspring","volume":"49","author":"Hoffman","year":"2014","journal-title":"Domest. Anim. Endocrinol"},{"key":"2024102510191879300_CIT0031","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S1043-2760(02)00697-5","article-title":"Fetal programming of the growth hormone\u2013insulin-like growth factor axis","volume":"13","author":"Holt","year":"2002","journal-title":"Trends Endocrinol. Metab"},{"key":"2024102510191879300_CIT0032","doi-asserted-by":"crossref","first-page":"skae002","DOI":"10.1093\/jas\/skae002","article-title":"Supplementing trace minerals to beef heifers during gestation; impacts on mineral status in the dam and offspring, performance, blood metabolite and hormone profiles, and puberty attainment in offspring raised and replacement heifers","volume":"102","author":"Hurlbert","year":"2024","journal-title":"J. Anim. Sci."},{"key":"2024102510191879300_CIT0033","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0020-7292(98)00060-5","article-title":"Insulin-like growth factor-1 in pregnancy","volume":"62","author":"Jernstr\u00f6m","year":"1998","journal-title":"Int J Gynaecol Obstet"},{"key":"2024102510191879300_CIT0034","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2337\/db08-0490","article-title":"Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice","volume":"58","author":"Jimenez-Chillaron","year":"2009","journal-title":"Diabetes"},{"key":"2024102510191879300_CIT0035","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/jn\/120.6.649","article-title":"Changes in liver and gastrointestinal tract energy demands in response to physiological workload in ruminants","volume":"120","author":"Johnson","year":"1990","journal-title":"J. Nutr"},{"key":"2024102510191879300_CIT0036","doi-asserted-by":"crossref","first-page":"E1619","DOI":"10.1073\/pnas.1204298109","article-title":"Functional roles of fructose","volume":"109","author":"Kim","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"2024102510191879300_CIT0037","doi-asserted-by":"crossref","first-page":"135","DOI":"10.15232\/S1080-7446(15)31392-9","article-title":"Reproductive ultrasonography for monitoring ovarian structure development, fetal development, embryo survival, and twins in beef cows","volume":"19","author":"Lamb","year":"2003","journal-title":"Prof. Anim. Sci"},{"key":"2024102510191879300_CIT0038","doi-asserted-by":"crossref","first-page":"E181","DOI":"10.2527\/jas.2009-2349","article-title":"Control of the estrous cycle to improve fertility for fixed-time artificial insemination in beef cattle: a review","volume":"88","author":"Lamb","year":"2010","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0039","doi-asserted-by":"crossref","first-page":"R71","DOI":"10.1152\/ajpregu.00341.2003","article-title":"Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin","volume":"286","author":"Lambert","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol"},{"key":"2024102510191879300_CIT0040","doi-asserted-by":"crossref","first-page":"e92592","DOI":"10.1371\/journal.pone.0092592","article-title":"Potential regulatory role of micrornas in the development of bovine gastrointestinal tract during early life","volume":"9","author":"Liang","year":"2014","journal-title":"PLoS One"},{"key":"2024102510191879300_CIT0041","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"2024102510191879300_CIT0042","first-page":"87","article-title":"The role of progesterone in maternal recognition of pregnancy in domestic ruminants","volume-title":"Regulation of implantation and establishment of pregnancy in mammals. Advances in anatomy, embryology and cell biology","author":"Lonergan","year":"2015"},{"key":"2024102510191879300_CIT0043","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1073\/pnas.0510452103","article-title":"Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency","volume":"103","author":"L\u00f3pez-Lluch","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2024102510191879300_CIT0044","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.anireprosci.2008.11.006","article-title":"Corpus luteum size and plasma progesterone concentration in cows","volume":"115","author":"Mann","year":"2009","journal-title":"Anim. Reprod. Sci"},{"key":"2024102510191879300_CIT0045","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.tvjl.2004.12.005","article-title":"Effects of time of progesterone supplementation on embryo development and interferon-\u03c4 production in the cow","volume":"171","author":"Mann","year":"2006","journal-title":"Vet. J"},{"key":"2024102510191879300_CIT0046","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.3390\/ani12151925","article-title":"Vitamin and mineral supplementation and rate of gain in beef heifers II: effects on concentration of trace minerals in maternal liver and fetal liver, muscle, allantoic, and amniotic fluids at day 83 of gestation","volume":"12","author":"McCarthy","year":"2022","journal-title":"Animals"},{"key":"2024102510191879300_CIT0047","doi-asserted-by":"crossref","first-page":"skab024","DOI":"10.1093\/jas\/skab024","article-title":"Vitamin and mineral supplementation and rate of gain during the first trimester of gestation affect concentrations of amino acids in maternal serum and allantoic fluid of beef heifers","volume":"99","author":"Menezes","year":"2021","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0048","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.3390\/ani12141757","article-title":"Vitamin and mineral supplementation and rate of gain in beef heifers I: effects on dam hormonal and metabolic status, fetal tissue and organ mass, and concentration of glucose and fructose in fetal fluids at d 83 of gestation","volume":"12","author":"Menezes","year":"2022","journal-title":"Animals"},{"key":"2024102510191879300_CIT0049","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3390\/metabo13020175","article-title":"Fetal hepatic lipidome is more greatly affected by maternal rate of gain compared with vitamin and mineral supplementation at day 83 of gestation","volume":"13","author":"Menezes","year":"2023","journal-title":"Metabolites"},{"key":"2024102510191879300_CIT0050","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.3168\/jds.2014-8734","article-title":"The somatotropic axis during the physiological estrus cycle in dairy heifers\u2014effect on hepatic expression of GHR and SOCS2","volume":"98","author":"Mense","year":"2015","journal-title":"J. Dairy Sci"},{"key":"2024102510191879300_CIT0051","volume-title":"Nutrient requirements of beef cattle","author":"NASEM","year":"2016","edition":"8th rev. ed."},{"key":"2024102510191879300_CIT0052","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1093\/ilar.47.1.73","article-title":"Animal models that elucidate basic principles of the developmental origins of adult diseases","volume":"47","author":"Nathanielsz","year":"2006","journal-title":"ILAR J"},{"key":"2024102510191879300_CIT0053","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/mrd.22021","article-title":"Multilevel regulation of steroid synthesis and metabolism in the bovine placenta","volume":"79","author":"Nguyen","year":"2012","journal-title":"Mol. Reprod. Dev"},{"key":"2024102510191879300_CIT0054","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.theriogenology.2020.03.011","article-title":"Late gestation heat stress in dairy cows: effects on dam and daughter","volume":"150","author":"Ouellet","year":"2020","journal-title":"Theriogenology"},{"key":"2024102510191879300_CIT0055","doi-asserted-by":"crossref","first-page":"skaa291","DOI":"10.1093\/jas\/skaa291","article-title":"Temperament influences mitochondrial capacity in skeletal muscle from 8 through 18 mo of age in Brahman heifers","volume":"98","author":"Owen","year":"2020","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0056","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.domaniend.2017.04.002","article-title":"Intergenerational impact of maternal overnutrition and obesity throughout pregnancy in sheep on metabolic syndrome in grandsons and granddaughters","volume":"60","author":"Pankey","year":"2017","journal-title":"Domest. Anim. Endocrinol"},{"key":"2024102510191879300_CIT0057","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.theriogenology.2016.04.051","article-title":"Factors affecting puberty in replacement beef heifers","volume":"86","author":"Perry","year":"2016","journal-title":"Theriogenology"},{"key":"2024102510191879300_CIT0058","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1042\/CS20070302","article-title":"Protein restriction during gestation and\/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats","volume":"114","author":"Pinheiro","year":"2008","journal-title":"Clin. Sci"},{"key":"2024102510191879300_CIT0059","doi-asserted-by":"crossref","first-page":"3342","DOI":"10.3390\/ijms19113342","article-title":"The pathophysiology of gestational diabetes mellitus","volume":"19","author":"Plows","year":"2018","journal-title":"Int. J. Mol. Sci"},{"key":"2024102510191879300_CIT0060","doi-asserted-by":"crossref","first-page":"5275","DOI":"10.1210\/en.2006-0288","article-title":"Epigenetic regulation of human trophoblastic cell migration and invasion","volume":"147","author":"Rahnama","year":"2006","journal-title":"Endocrinology"},{"key":"2024102510191879300_CIT0061","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/1440-1681.12162","article-title":"Fructose, pregnancy and later life impacts","volume":"40","author":"Regnault","year":"2013","journal-title":"Clin. Exp. Pharmacol. Physiol"},{"key":"2024102510191879300_CIT0062","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.cvfa.2019.02.006","article-title":"Developmental programming of fetal growth and development","volume":"35","author":"Reynolds","year":"2019","journal-title":"Vet. Clin. North Am. Food Anim. Pract"},{"key":"2024102510191879300_CIT0063","doi-asserted-by":"crossref","first-page":"107322","DOI":"10.1016\/j.anireprosci.2023.107322","article-title":"Role of the placenta in developmental programming: observations from models using large animals","volume":"257","author":"Reynolds","year":"2023","journal-title":"Anim. Reprod. Sci"},{"key":"2024102510191879300_CIT0064","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s12041-017-0788-5","article-title":"The placental gateway of maternal transgenerational epigenetic inheritance","volume":"96","author":"Sailasree","year":"2017","journal-title":"J. Genet"},{"key":"2024102510191879300_CIT0065","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.3168\/jds.S0022-0302(02)74368-3","article-title":"Ovarian structures and circulating steroids in heifers and lactating cows in summer and lactating and dry cows in winter","volume":"85","author":"Sartori","year":"2002","journal-title":"J. Dairy Sci"},{"key":"2024102510191879300_CIT0066","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1113\/jphysiol.2010.198622","article-title":"The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth","volume":"589","author":"Sferruzzi-Perri","year":"2011","journal-title":"J. Physiol"},{"key":"2024102510191879300_CIT0067","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/ijo.2014.190","article-title":"Multigenerational impact of maternal overnutrition\/obesity in the sheep on the neonatal leptin surge in granddaughters","volume":"39","author":"Shasa","year":"2015","journal-title":"Int. J. Obes. (Lond.)"},{"key":"2024102510191879300_CIT0068","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/pr.2013.2","article-title":"Fetal metabolic programming and epigenetic modifications: a systems biology approach","volume":"73","author":"Sookoian","year":"2013","journal-title":"Pediatr. Res"},{"key":"2024102510191879300_CIT0069","doi-asserted-by":"crossref","first-page":"12722","DOI":"10.3390\/ijms222312722","article-title":"Placental endocrine activity: adaptation and disruption of maternal glucose metabolism in pregnancy and the influence of fetal sex","volume":"22","author":"Stern","year":"2021","journal-title":"Int. J. Mol. Sci"},{"key":"2024102510191879300_CIT0070","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1530\/rep.0.1210777","article-title":"Appearance and number of follicles and change in the concentration of serum FSH in female bovine fetuses","volume":"121","author":"Tanaka","year":"2001","journal-title":"Reproduction"},{"key":"2024102510191879300_CIT0071","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.domaniend.2008.07.002","article-title":"The role of endocrine insulin-like growth factor-I (IGF-I) in female bovine reproduction","volume":"35","author":"Velazquez","year":"2008","journal-title":"Domest. Anim. Endocrinol"},{"key":"2024102510191879300_CIT0072","doi-asserted-by":"crossref","first-page":"skac319","DOI":"10.1093\/jas\/skac319","article-title":"A review of the effect of nutrient and energy restriction during late gestation on beef cattle offspring growth and development","volume":"101","author":"Waldon","year":"2023","journal-title":"J. Anim. Sci"},{"key":"2024102510191879300_CIT0073","first-page":"0025","article-title":"Age- and microbiota-dependent cell stemness plasticity revealed by cattle cell landscape","volume":"6","author":"Wu","year":"2023","journal-title":"Research (Washington, D.C.)"},{"key":"2024102510191879300_CIT0074","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1095\/biolreprod.107.066688","article-title":"The capacity of primordial follicles in fetal bovine ovaries to initiate growth in vitro develops during mid-gestation and is associated with meiotic arrest of oocytes","volume":"78","author":"Yang","year":"2008","journal-title":"Biol. Reprod"},{"key":"2024102510191879300_CIT0075","first-page":"1327","article-title":"Plasticity in gastrointestinal morphology and enzyme activity in lactating striped hamsters (Cricetulus barabensis)","volume":"219","author":"Zhang","year":"2016","journal-title":"J. Exp. Biol"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jas\/advance-article-pdf\/doi\/10.1093\/jas\/skae295\/59352018\/skae295.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skae295\/60081510\/skae295.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skae295\/60081510\/skae295.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T10:19:56Z","timestamp":1729851596000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/doi\/10.1093\/jas\/skae295\/7776031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":75,"URL":"https:\/\/doi.org\/10.1093\/jas\/skae295","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024]]},"published":{"date-parts":[[2024]]},"article-number":"skae295"}}