{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:58:24Z","timestamp":1789552704913,"version":"build-2803163510"},"reference-count":61,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":346,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Maternal nutrition during gestation is a key determinant of maternal physiological adaptations and offspring developmental outcomes. This study evaluated how two total mixed ration (TMR)-based silages offered during mid-gestation influenced nutrient utilization, systemic physiology, uterine hemodynamics, and performance of pregnant beef cows and their offspring. Thirty-three multiparous Tabapu\u00e3 cows (Bos taurus indicus) received one of the following treatments from day 130 to 230 of gestation: (1) TMR silage composed of Marandu grass and dried distillers\u2019 grains plus soluble (DDGS; n\u2009=\u200917); or (2) TMR silage composed of Marandu grass, soybean hulls (SH), and urea (n\u2009=\u200916). At day 230, all cows were regrouped and managed on pasture until calving. Cow\u2013calf pairs remained together until weaning (\u223c175 d), after which calves were individually housed and monitored for 100 d. Maternal digestibility, nitrogen balance, and microbial protein synthesis were assessed at d 180; uterine blood flow was evaluated by Doppler ultrasonography at day 230 and 270; and maternal blood metabolites were measured at d 230. Statistical significance was declared at P\u2009\u2264\u20090.05. Cows fed DDGS-based TMR silage had greater dry matter (DM), crude protein, and neutral detergent fiber intakes (P\u2009\u2264\u20090.01), improved DM digestibility (P\u2009=\u20090.04), and increased nitrogen retention (P\u2009&amp;lt;\u20090.001) compared with SH + urea-based TMR fed cows. At day 230, DDGS-fed cows exhibited greater body weight (BW) and body condition score (BCS; P\u2009\u2264\u20090.04) and maintained higher BCS at calving (P\u2009&amp;lt;\u20090.01). Non-esterified fatty acids and beta-hydroxybutyrate concentrations were greater in SH + urea-fed cows (P\u2009\u2264\u20090.02), as was preprandial urea concentration (P\u2009&amp;lt;\u20090.01). At day 230, cows fed SH + urea and carrying female fetuses had greater pulsatility index, resistance index, and systolic\/diastolic ratio (P\u2009\u2264\u20090.03). Maternal diet did not affect calf BW at birth, preweaning growth, or backgrounding performance (P\u2009\u2265\u20090.20). Milk yield tended to be greater at 60\u2009d in milk (DIM) in SH-fed cows (P\u2009=\u20090.07), whereas milk composition was unaffected at either 60 or 120 DIM (P\u2009\u2265\u20090.21). Overall, mid-gestation supplementation with DDGS-based TMR silage improved maternal nutrient status, body condition, and uteroplacental adaptations, but no consistent effects on offspring growth were detected.<\/jats:p>","DOI":"10.1093\/jas\/skaf430","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T13:12:48Z","timestamp":1765458768000},"source":"Crossref","is-referenced-by-count":3,"title":["Effects of mid-gestation supplementation with dried distillers\u2019 grains and soybean hull-based total mixed ration silages on maternal metabolism, uteroplacental hemodynamics, and offspring development in beef cows"],"prefix":"10.1093","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5425-700X","authenticated-orcid":false,"given":"Karolina B","family":"Nascimento","sequence":"first","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robson L","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius D","family":"Vaz","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier A M","family":"Meneses","sequence":"additional","affiliation":[{"name":"Department of Medicine Veterinary and Animal Science, Universidad de Ciencias Aplicadas y Ambientales (UDCA) , Cartagena 130001,","place":["Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R","family":"Casagrande","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5168-4794","authenticated-orcid":false,"given":"Mateus P","family":"Gionbelli","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2479-922X","authenticated-orcid":false,"given":"Thiago F","family":"Bernardes","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lavras , Lavras 37203-202,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"2026010223413962800_skaf430-B1","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fped.2019.00022","article-title":"Sex differences in nutrition, growth, and metabolism in preterm infants","volume":"7","author":"Alur","year":"2019","journal-title":"Front. 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