{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:48:35Z","timestamp":1791884915590,"version":"4.3.4"},"reference-count":58,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":257,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Improving sperm motility and preservation duration is crucial for enhancing reproductive efficiency in dairy goats. Given the decline of gamma-aminobutyric acid (GABA) during in vitro storage, this study evaluated its effects and mechanisms on buck semen via diet and extender supplementation. Dietary GABA supplementation significantly increased ruminal total volatile fatty acids (P\u2009&amp;lt;\u20090.01) and ammonia nitrogen levels (P\u2009&amp;lt;\u20090.05), enriched beneficial bacteria, enhanced serum antioxidant capacity (P\u2009&amp;lt;\u20090.05), and improved sperm motility, velocity, acrosome and plasma membrane integrity (P\u2009&amp;lt;\u20090.05). Although GABA did not cross the blood\u2013testis barrier, it significantly elevated serum LH and testosterone levels (P\u2009&amp;lt;\u20090.01). In the in vitro preservation experiment, adding 1.0\u2009g\/L GABA to the extender significantly improved sperm viability, kinematic parameters, antioxidant capacity, acrosome and membrane integrity on days 3 and 5 of storage (P\u2009&amp;lt;\u20090.05), while reducing reactive oxygen species (ROS) and malondialdehyde (MDA) levels (P\u2009&amp;lt;\u20090.05). Proteomic analysis revealed that GABA upregulated membrane structure-related proteins, and PLA2G10-mediated changes in phospholipase A2 (PLA2) activity were identified as a key mechanism by which GABA modulates sperm membrane structure and motility. Inhibition of PLA2G10 with LY329722 significantly abrogated the protective effects of GABA (P\u2009&amp;lt;\u20090.01). GABA not only indirectly improves buck semen quality by modulating the rumen microbiota and hypothalamic\u2013pituitary\u2013testicular axis but also directly enhances in vitro sperm preservation through PLA2G10-mediated membrane remodeling. GABA can serve as a functional feed additive and a semen extender protectant to effectively improve reproductive management in ruminants.<\/jats:p>","DOI":"10.1093\/jas\/skag294","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T11:43:05Z","timestamp":1789213385000},"source":"Crossref","is-referenced-by-count":0,"title":["Gamma-aminobutyric acid modulates buck semen quality and sperm preservation duration in vivo and in vitro"],"prefix":"10.1093","volume":"104","author":[{"given":"Jintao","family":"Li","sequence":"first","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangqi","family":"Yang","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runyu","family":"Yang","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiping","family":"Shi","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University , Yangling 712100,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"2026101305262969200_skag294-B1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23148033","article-title":"Treatment of mouse sperm with a non-catalytic mutant of PLA2G10 reveals that PLA2G10 improves in vitro fertilization through both its enzymatic activity and as ligand of PLA2R1","volume":"23","author":"Abi Nahed","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2026101305262969200_skag294-B2","doi-asserted-by":"publisher","first-page":"e13656","DOI":"10.1111\/acel.13656","article-title":"Integrity of hypothalamic-pituitary-testicular axis in exceptional longevity","volume":"21","author":"Aleksic","year":"2022","journal-title":"Aging Cell"},{"key":"2026101305262969200_skag294-B3","doi-asserted-by":"publisher","first-page":"105236","DOI":"10.1016\/j.cryobiol.2025.105236","article-title":"Mitochondrial uncoupling and glycolysis stimulation are beneficial for kinematics, functionality and oxidative homeostasis of cryopreserved ram sperm","volume":"119","author":"Alves","year":"2025","journal-title":"Cryobiology"},{"key":"2026101305262969200_skag294-B4","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1038\/s41586-024-07336-w","article-title":"Paternal microbiome perturbations impact offspring fitness","volume":"629","author":"Argaw-Denboba","year":"2024","journal-title":"Nature"},{"key":"2026101305262969200_skag294-B5","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.3168\/jds.S0022-0302(67)87575-1","article-title":"Rumen pH as a factor for controlling feed intake in ruminants","volume":"50","author":"Bhattacharya","year":"1967","journal-title":"J Dairy Sci"},{"key":"2026101305262969200_skag294-B6","doi-asserted-by":"publisher","first-page":"152773","DOI":"10.1016\/j.scitotenv.2021.152773","article-title":"Biotechnological potential of rumen microbiota for sustainable bioconversion of lignocellulosic waste to biofuels and value-added products","volume":"814","author":"Bhujbal","year":"2022","journal-title":"Sci Total Environ"},{"key":"2026101305262969200_skag294-B7","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1111\/jpn.13280","article-title":"Effects of dietary \u03b3-aminobutyric acid supplementation on antioxidant status, blood hormones and meat quality in growing-finishing pigs undergoing transport stress","volume":"104","author":"Bi","year":"2020","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"key":"2026101305262969200_skag294-B8","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1039\/c8fo02161a","article-title":"Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets","volume":"10","author":"Chen","year":"2019","journal-title":"Food Funct"},{"key":"2026101305262969200_skag294-B9","doi-asserted-by":"publisher","first-page":"4692","DOI":"10.1016\/j.febslet.2005.06.090","article-title":"GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1\/2 during acrosomal exocytosis in Guinea pig spermatozoa","volume":"579","author":"Chen","year":"2005","journal-title":"FEBS Lett"},{"key":"2026101305262969200_skag294-B10","doi-asserted-by":"publisher","first-page":"2463533","DOI":"10.1080\/09513590.2025.2463533","article-title":"Dysregulated serum levels of kisspeptin, NKB, GABA in women with polycystic ovary syndrome and their association with hormonal profiles","volume":"41","author":"Cheng","year":"2025","journal-title":"Gynecol Endocrinol"},{"key":"2026101305262969200_skag294-B11","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1159\/000089556","article-title":"Insights into GABA receptor signalling in TM3 Leydig cells","volume":"81","author":"Doepner","year":"2005","journal-title":"Neuroendocrinology"},{"key":"2026101305262969200_skag294-B12","doi-asserted-by":"publisher","first-page":"1285466","DOI":"10.3389\/fmicb.2023.1285466","article-title":"Effects of guanidinoacetic acid on in vitro rumen fermentation and microflora structure and predicted gene function","volume":"14","author":"Dong","year":"2023","journal-title":"Front Microbiol"},{"key":"2026101305262969200_skag294-B13","first-page":"435","article-title":"The occurrence of GABA in vas deferens, prostate, epididymis, seminal vesicle and testicle of the rat","volume":"34","author":"Erd\u00f6","year":"1983","journal-title":"Acta Biol Hung"},{"key":"2026101305262969200_skag294-B14","doi-asserted-by":"publisher","first-page":"2601","DOI":"10.1002\/jcp.22606","article-title":"Group X secreted phospholipase A\u2082 specifically decreases sperm motility in mice","volume":"226","author":"Escoffier","year":"2011","journal-title":"J Cell Physiol"},{"key":"2026101305262969200_skag294-B15","doi-asserted-by":"publisher","DOI":"10.3390\/antiox14111350","article-title":"MitoQ as a mitochondria-targeted antioxidant in sperm cryopreservation: an updated review on its mechanisms, efficacy, and future perspectives","volume":"14","author":"Farshad","year":"2025","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"2026101305262969200_skag294-B16","doi-asserted-by":"publisher","first-page":"2185861","DOI":"10.1080\/10253890.2023.2185861","article-title":"Gamma-amino butyric acid (GABA) supplementation alleviates dexamethasone treatment-induced oxidative stress and inflammation response in broiler chickens","volume":"26","author":"Fathi","year":"2023","journal-title":"Stress (Amsterdam, Netherlands)"},{"key":"2026101305262969200_skag294-B17","doi-asserted-by":"publisher","first-page":"e0197897","DOI":"10.1371\/journal.pone.0197897","article-title":"Incubation of human sperm with micelles made from glycerophospholipid mixtures increases sperm motility and resistance to oxidative stress","volume":"13","author":"Ferreira","year":"2018","journal-title":"PLoS One"},{"key":"2026101305262969200_skag294-B18","doi-asserted-by":"publisher","first-page":"115925","DOI":"10.1016\/j.envres.2023.115925","article-title":"Lignocellulose degradation by rumen bacterial communities: New insights from metagenome analyses","volume":"229","author":"Gharechahi","year":"2023","journal-title":"Environ Res"},{"key":"2026101305262969200_skag294-B19","doi-asserted-by":"publisher","first-page":"169063","DOI":"10.1016\/j.jmb.2025.169063","article-title":"TamL is a key player of the outer membrane homeostasis in bacteroidota","volume":"437","author":"Giovannercole","year":"2025","journal-title":"J Mol Biol"},{"key":"2026101305262969200_skag294-B20","doi-asserted-by":"publisher","first-page":"106600","DOI":"10.1016\/j.anireprosci.2020.106600","article-title":"Effects of gonadotropins on testis cell subpopulations of newly hatched chicks treated during embryonic development","volume":"222","author":"Gonz\u00e1lez-Mor\u00e1n","year":"2020","journal-title":"Anim Reprod Sci"},{"key":"2026101305262969200_skag294-B21","doi-asserted-by":"publisher","first-page":"100930","DOI":"10.1016\/j.repbio.2024.100930","article-title":"Effect of resveratrol on spermatogenesis in breeding boars and the proteomic analysis for testes","volume":"24","author":"Guo","year":"2024","journal-title":"Reprod Biol"},{"key":"2026101305262969200_skag294-B22","doi-asserted-by":"publisher","first-page":"419","DOI":"10.14202\/vetworld.2022.419-426","article-title":"Effect of vitamin E supplementation on chicken sperm quality: a meta-analysis","volume":"15","author":"Hayanti","year":"2022","journal-title":"Vet World"},{"key":"2026101305262969200_skag294-B23","doi-asserted-by":"publisher","first-page":"117704","DOI":"10.1016\/j.lfs.2020.117704","article-title":"The adverse effects of psychotropic drugs as an endocrine disrupting chemicals on the hypothalamic-pituitary regulation in male","volume":"253","author":"Ilgin","year":"2020","journal-title":"Life Sci"},{"key":"2026101305262969200_skag294-B24","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s40168-022-01298-9","article-title":"Metagenomic insights into the microbe-mediated B and K(2) vitamin biosynthesis in the gastrointestinal microbiome of ruminants","volume":"10","author":"Jiang","year":"2022","journal-title":"Microbiome"},{"key":"2026101305262969200_skag294-B25","doi-asserted-by":"publisher","first-page":"e13551","DOI":"10.1111\/cpr.13551","article-title":"Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120","volume":"57","author":"Jing","year":"2024","journal-title":"Cell Prolif"},{"key":"2026101305262969200_skag294-B26","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1111\/rda.12932","article-title":"Effects of supplemental conjugated linoleic acids (CLA) on fresh and post-thaw sperm quality of Holstein bulls","volume":"52","author":"Karimi","year":"2017","journal-title":"Reprod Domest Anim"},{"key":"2026101305262969200_skag294-B27","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1262\/jrd.2019-008","article-title":"Capacitation of mouse sperm is modulated by gamma-aminobutyric acid (GABA) concentration","volume":"65","author":"Kurata","year":"2019","journal-title":"J Reprod Dev"},{"key":"2026101305262969200_skag294-B28","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1007\/bf00238029","article-title":"Involvement of preoptic-anterior hypothalamic GABA neurons in the regulation of pituitary LH and prolactin release","volume":"52","author":"Lamberts","year":"1983","journal-title":"Exp Brain Res"},{"key":"2026101305262969200_skag294-B29","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12030772","article-title":"Dietary guanidine acetic acid improves ruminal antioxidant capacity and alters rumen fermentation and microflora in rapid-growing lambs","volume":"12","author":"Li","year":"2023","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"2026101305262969200_skag294-B30","doi-asserted-by":"publisher","first-page":"108308","DOI":"10.1016\/j.biotechadv.2024.108308","article-title":"Rumen microbes, enzymes, metabolisms, and application in lignocellulosic waste conversion - a comprehensive review","volume":"71","author":"Liang","year":"2024","journal-title":"Biotechnol Adv"},{"key":"2026101305262969200_skag294-B31","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1007\/s40618-020-01481-5","article-title":"Gut microbiota alterations reveal potential gut-brain axis changes in polycystic ovary syndrome","volume":"44","author":"Liang","year":"2021","journal-title":"J Endocrinol Invest"},{"key":"2026101305262969200_skag294-B32","doi-asserted-by":"publisher","first-page":"574856","DOI":"10.3389\/fphys.2020.574856","article-title":"Metabolite support of long-term storage of sperm in the spermatheca of honeybee (Apis mellifera) queens","volume":"11","author":"Liu","year":"2020","journal-title":"Front Physiol"},{"key":"2026101305262969200_skag294-B33","doi-asserted-by":"publisher","first-page":"102004","DOI":"10.1016\/j.molmet.2024.102004","article-title":"Maternal gut bifidobacterium breve modifies fetal brain metabolism in germ-free mice","volume":"88","author":"Lopez-Tello","year":"2024","journal-title":"Mol Metab"},{"key":"2026101305262969200_skag294-B34","doi-asserted-by":"publisher","first-page":"888023","DOI":"10.3389\/fvets.2022.888023","article-title":"Commensal lactobacilli enhance sperm qualitative parameters in dogs","volume":"9","author":"Mahiddine","year":"2022","journal-title":"Front Vet Sci"},{"key":"2026101305262969200_skag294-B35","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2174\/1570159x22666240815120244","article-title":"Depression and the glutamate\/GABA-glutamine cycle","volume":"23","author":"Mamelak","year":"2024","journal-title":"Curr Neuropharmacol"},{"key":"2026101305262969200_skag294-B36","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.5713\/ajas.19.0785","article-title":"Effect of \u03b3-aminobutyric acid producing bacteria on in vitro rumen fermentation, growth performance, and meat quality of Hanwoo steers","volume":"33","author":"Mamuad","year":"2020","journal-title":"Asian-Australas J Anim Sci"},{"key":"2026101305262969200_skag294-B37","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1080\/08927014.2016.1232716","article-title":"Bioemulsifier (BE-AM1) produced by Solibacillus silvestris AM1 is a functional amyloid that modulates bacterial cell-surface properties","volume":"32","author":"Markande","year":"2016","journal-title":"Biofouling"},{"key":"2026101305262969200_skag294-B38","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.3389\/fmicb.2016.01934","article-title":"The neuro-endocrinological role of microbial glutamate and GABA signaling","volume":"7","author":"Mazzoli","year":"2016","journal-title":"Front Microbiol"},{"key":"2026101305262969200_skag294-B39","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1017\/s096719942400042x","article-title":"Effect of dehydroleucodine (DhL) on the acrosome reaction in sperm of Chinchilla lanigera: signalling pathways involved","volume":"32","author":"Medina","year":"2024","journal-title":"Zygote (Cambridge, England)"},{"key":"2026101305262969200_skag294-B40","doi-asserted-by":"publisher","first-page":"12994","DOI":"10.1038\/s41598-017-13411-2","article-title":"Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A(2) activity impair the in vitro sperm fertilizing competence in mice","volume":"7","author":"Moawad","year":"2017","journal-title":"Sci Rep"},{"key":"2026101305262969200_skag294-B41","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1016\/j.chom.2025.09.006","article-title":"The microbiota extends the reproductive lifespan of mice by safeguarding the ovarian reserve","volume":"33","author":"Munyoki","year":"2025","journal-title":"Cell Host Microbe"},{"key":"2026101305262969200_skag294-B42","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1111\/andr.12351","article-title":"Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms","volume":"5","author":"Najafipour","year":"2017","journal-title":"Andrology"},{"key":"2026101305262969200_skag294-B43","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s12866-023-03173-5","article-title":"Characteristics of gut microbiota in patients with asthenozoospermia: a Chinese pilot study","volume":"24","author":"Pan","year":"2024","journal-title":"BMC Microbiol"},{"key":"2026101305262969200_skag294-B44","doi-asserted-by":"publisher","first-page":"40236","DOI":"10.1038\/srep40236","article-title":"Insights into the molecular basis of long-term storage and survival of sperm in the honeybee (Apis mellifera)","volume":"7","author":"Paynter","year":"2017","journal-title":"Sci Rep"},{"key":"2026101305262969200_skag294-B45","doi-asserted-by":"publisher","first-page":"115050","DOI":"10.1016\/j.expneurol.2024.115050","article-title":"Modulation of GABAergic system as a therapeutic option in stroke","volume":"384","author":"Perovic","year":"2025","journal-title":"Exp Neurol"},{"key":"2026101305262969200_skag294-B46","doi-asserted-by":"publisher","first-page":"4721","DOI":"10.1007\/s12011-021-02590-9","article-title":"Effect of supplementation of zinc-methionine on egg production, semen quality, reproductive hormones, and hatchability in broiler breeders","volume":"199","author":"Prabakar","year":"2021","journal-title":"Biol Trace Elem Res"},{"key":"2026101305262969200_skag294-B47","doi-asserted-by":"publisher","first-page":"eadk1887","DOI":"10.1126\/sciadv.adk1887","article-title":"The maternal microbiome promotes placental development in mice","volume":"9","author":"Pronovost","year":"2023","journal-title":"Sci Adv"},{"key":"2026101305262969200_skag294-B48","doi-asserted-by":"publisher","first-page":"101908","DOI":"10.1016\/j.psj.2022.101908","article-title":"Effects of dietary supplementation of different sources and levels of selenium on the semen quality and reproductive performance in aged broiler breeder roosters","volume":"101","author":"Sabzian-Melei","year":"2022","journal-title":"Poult Sci"},{"key":"2026101305262969200_skag294-B49","doi-asserted-by":"publisher","first-page":"104803","DOI":"10.1016\/j.psj.2025.104803","article-title":"Research note: Effects of L-carnitine and L-arginine on sperm quality and fertility potential of aged broiler breeder roosters","volume":"104","author":"Samiei","year":"2025","journal-title":"Poult Sci"},{"key":"2026101305262969200_skag294-B50","doi-asserted-by":"publisher","first-page":"149596","DOI":"10.1016\/j.scitotenv.2021.149596","article-title":"Amino acids metabolism by rumen microorganisms: Nutrition and ecology strategies to reduce nitrogen emissions from the inside to the outside","volume":"800","author":"Tan","year":"2021","journal-title":"Sci Total Environ"},{"key":"2026101305262969200_skag294-B51","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1111\/epi.18202","article-title":"Asymmetric dynamics of GABAergic system and paradoxical responses of GABAergic neurons in piriform seizures","volume":"66","author":"Tao","year":"2025","journal-title":"Epilepsia"},{"key":"2026101305262969200_skag294-B52","doi-asserted-by":"publisher","first-page":"132400","DOI":"10.1016\/j.foodchem.2022.132400","article-title":"Exogenous GABA improves the antioxidant and anti-aging ability of silkworm (Bombyx mori)","volume":"383","author":"Tu","year":"2022","journal-title":"Food Chem"},{"key":"2026101305262969200_skag294-B53","doi-asserted-by":"publisher","first-page":"24337","DOI":"10.1038\/s41598-021-03553-9","article-title":"Comparison of HPLC and NMR for quantification of the main volatile fatty acids in rumen digesta","volume":"11","author":"Wang","year":"2021","journal-title":"Sci Rep"},{"key":"2026101305262969200_skag294-B54","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.theriogenology.2023.07.009","article-title":"Comparative analysis of different metabolites in semen of Guanzhong dairy goats with different motility rates","volume":"210","author":"Yuan","year":"2023","journal-title":"Theriogenology"},{"key":"2026101305262969200_skag294-B55","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1002\/ptr.6608","article-title":"Lycopene improves sperm quality: A promising nutrient for the treatment of male infertility","volume":"34","author":"Zhai","year":"2020","journal-title":"Phytother Res"},{"key":"2026101305262969200_skag294-B56","doi-asserted-by":"publisher","first-page":"849529","DOI":"10.3389\/fnut.2022.849529","article-title":"The effects of GABA-rich adzuki beans on glycolipid metabolism, as well as intestinal flora, in type 2 diabetic mice","volume":"9","author":"Zhang","year":"2022","journal-title":"Front Nutr"},{"key":"2026101305262969200_skag294-B57","doi-asserted-by":"publisher","first-page":"113846","DOI":"10.1016\/j.ecoenv.2022.113846","article-title":"Vitamin C supplementation rescued meiotic arrest of spermatocytes in Balb\/c mice exposed to BDE-209","volume":"242","author":"Zhang","year":"2022","journal-title":"Ecotoxicol Environ Saf"},{"key":"2026101305262969200_skag294-B58","doi-asserted-by":"publisher","first-page":"101493","DOI":"10.1016\/j.animal.2025.101493","article-title":"The effects of gamma-aminobutyric acid on growth performance, diarrhoea, ruminal fermentation, and antioxidant capacity in pre-weaned calves","volume":"19","author":"Zhang","year":"2025","journal-title":"Animal"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jas\/advance-article-pdf\/doi\/10.1093\/jas\/skag294\/71089444\/skag294.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skag294\/71089444\/skag294.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jas\/article-pdf\/doi\/10.1093\/jas\/skag294\/71089444\/skag294.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:26:39Z","timestamp":1791883599000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/doi\/10.1093\/jas\/skag294\/8796068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":58,"URL":"https:\/\/doi.org\/10.1093\/jas\/skag294","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026]]},"published":{"date-parts":[[2026]]},"article-number":"skag294"}}