{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T15:07:32Z","timestamp":1780672052348,"version":"3.54.1"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31402089"],"award-info":[{"award-number":["31402089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31330075"],"award-info":[{"award-number":["31330075"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31472106"],"award-info":[{"award-number":["31472106"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31272261"],"award-info":[{"award-number":["31272261"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Key Programs of Frontier Scientific Research of the Chinese Academy of Sciences"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,3]]},"DOI":"10.1093\/jas\/skx003","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T11:32:16Z","timestamp":1516793536000},"page":"1130-1139","source":"Crossref","is-referenced-by-count":31,"title":["The effects of dietary sulfur amino acids on growth performance, intestinal morphology, enzyme activity, and nutrient transporters in weaning piglets1"],"prefix":"10.1093","volume":"96","author":[{"given":"Enyan","family":"Zong","sequence":"first","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Huang","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"},{"name":"Chinese Academy of Science, Institute of Subtropical Agriculture, Research Center for Healthy Breeding of Livestock and Poultry, Hunan Engineering and Research Center of Animal and Poultry Science, Changsha City, Hunan, China"},{"name":"Key Laboratory for Agroecological Processes in Subtropical Region, Scientific Observation and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Li","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Li","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqing","family":"Ding","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Xiong","sequence":"additional","affiliation":[{"name":"Chinese Academy of Science, Institute of Subtropical Agriculture, Research Center for Healthy Breeding of Livestock and Poultry, Hunan Engineering and Research Center of Animal and Poultry Science, Changsha City, Hunan, China"},{"name":"Key Laboratory for Agroecological Processes in Subtropical Region, Scientific Observation and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Yin","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"},{"name":"Chinese Academy of Science, Institute of Subtropical Agriculture, Research Center for Healthy Breeding of Livestock and Poultry, Hunan Engineering and Research Center of Animal and Poultry Science, Changsha City, Hunan, China"},{"name":"Key Laboratory for Agroecological Processes in Subtropical Region, Scientific Observation and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huansheng","family":"Yang","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, China"},{"name":"Chinese Academy of Science, Institute of Subtropical Agriculture, Research Center for Healthy Breeding of Livestock and Poultry, Hunan Engineering and Research Center of Animal and Poultry Science, Changsha City, Hunan, China"},{"name":"Key Laboratory for Agroecological Processes in Subtropical Region, Scientific Observation and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha City, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"key\n\t\t\t\t20180403133401_CIT0001","first-page":"G619","article-title":"Oral IGF-I enhances nutrient and electrolyte absorption in neonatal piglet intestine","volume":"277","author":"Alexander","year":"1999","journal-title":"Am. J. Physiol"},{"key":"key\n\t\t\t\t20180403133401_CIT0002","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1017\/S0954422409990138","article-title":"Intestinal metabolism of sulfur amino acids","volume":"22","author":"Bauchart-Thevret","year":"2009","journal-title":"Nutr. Res. Rev"},{"key":"key\n\t\t\t\t20180403133401_CIT0003","doi-asserted-by":"crossref","first-page":"E1239","DOI":"10.1152\/ajpendo.91021.2008","article-title":"Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs","volume":"296","author":"Bauchart-Thevret","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab"},{"key":"key\n\t\t\t\t20180403133401_CIT0004","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/s00726-014-1675-5","article-title":"L-methionine supplementation maintains the integrity and barrier function of the small-intestinal mucosa in post-weaning piglets","volume":"46","author":"Chen","year":"2014","journal-title":"Amino Acids"},{"key":"key\n\t\t\t\t20180403133401_CIT0005","doi-asserted-by":"crossref","first-page":"e0165585","DOI":"10.1371\/journal.pone.0165585","article-title":"Transmissible gastroenteritis virus infection enhances SGLT1 and GLUT2 expression to increase glucose uptake","volume":"11","author":"Dai","year":"2016","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180403133401_CIT0006","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00075197-200201000-00015","article-title":"Redox control of the transsulfuration and glutathione biosynthesis pathways","volume":"5","author":"Deplancke","year":"2002","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"key\n\t\t\t\t20180403133401_CIT0007","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.anifeedsci.2009.11.001","article-title":"Dietary preference for methionine sources in weaned pigs","volume":"155","author":"Ettle","year":"2010","journal-title":"Anim. Feed. Sci. Tech"},{"key":"key\n\t\t\t\t20180403133401_CIT0008","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2337\/db11-1029","article-title":"Na+-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion","volume":"61","author":"Gorboulev","year":"2012","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t20180403133401_CIT0009","doi-asserted-by":"crossref","first-page":"C385","DOI":"10.1152\/ajpcell.1995.269.2.C385","article-title":"Pattern of rat intestinal brush border enzyme gene expression changes with epithelial growth state","volume":"269","author":"Hodin","year":"1995","journal-title":"Am. J. Physiol"},{"key":"key\n\t\t\t\t20180403133401_CIT0010","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1439-0396.2009.00920.x","article-title":"Effects of adding liquid DL-methionine hydroxy analogue-free acid to drinking water on growth performance and small intestinal morphology of nursery pigs","volume":"94","author":"Kaewtapee","year":"2010","journal-title":"J. Anim. Physiol. Anim. Nutr"},{"key":"key\n\t\t\t\t20180403133401_CIT0011","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.5713\/ajas.15.0579","article-title":"Effects of supplemental liquid DL-methionine hydroxy analog free acid in diet on growth performance and gastrointestinal functions of piglets","volume":"29","author":"Kaewtapee","year":"2016","journal-title":"Asian-Australas. J. Anim. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0012","doi-asserted-by":"crossref","first-page":"104","DOI":"10.2527\/2006.841104x","article-title":"Efficacy of DL-methionine hydroxy analog free acid and DL-methionine as methionine sources for pigs","volume":"84","author":"Kim","year":"2006","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0013","doi-asserted-by":"crossref","first-page":"123","DOI":"10.17221\/8077-CJAS","article-title":"Effect of source of methionine in broken rice-soybean diet on production performance, blood chemistry, and fermentation characteristics in weaned pigs","volume":"60","author":"Krutthai","year":"2015","journal-title":"Czech J. Anim. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0014","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3945\/jn.109.117267","article-title":"Early weaning reduces small intestinal alkaline phosphatase expression in pigs","volume":"140","author":"Lackeyram","year":"2010","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t20180403133401_CIT0015","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s11250-011-9904-3","article-title":"Pig performance increases with the addition of DL-methionine and L-lysine to ensiled cassava leaf protein diets","volume":"44","author":"Ly","year":"2012","journal-title":"Trop. Anim. Health. Prod"},{"key":"key\n\t\t\t\t20180403133401_CIT0016","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1002\/jps.22277","article-title":"Peptide transporter 1 is responsible for intestinal uptake of the dipeptide glycylsarcosine: studies in everted jejunal rings from wild-type and Pept1 null mice","volume":"100","author":"Ma","year":"2011","journal-title":"J. Pharm. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0017","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.2527\/2001.7961557x","article-title":"Estimation of the total sulfur amino acid requirement and the effect of betaine in diets deficient in total sulfur amino acids for the weanling pig","volume":"79","author":"Matthews","year":"2001","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0018","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1017\/S000711450720580X","article-title":"Main intestinal markers associated with the changes in gut architecture and function in piglets after weaning","volume":"97","author":"Montagne","year":"2007","journal-title":"Br. J. Nutr"},{"key":"key\n\t\t\t\t20180403133401_CIT0019","doi-asserted-by":"crossref","first-page":"G173","DOI":"10.1152\/ajpgi.00197.2006","article-title":"Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig","volume":"292","author":"Moeser","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"key\n\t\t\t\t20180403133401_CIT0020","doi-asserted-by":"crossref","first-page":"G413","DOI":"10.1152\/ajpgi.00304.2006","article-title":"Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs","volume":"293","author":"Moeser","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"key\n\t\t\t\t20180403133401_CIT0021","volume-title":"Nutrient requirements of swine","author":"National Research Council","year":"2012","edition":"11th ed"},{"key":"key\n\t\t\t\t20180403133401_CIT0022","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0009-9120(03)00096-1","article-title":"Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility","volume":"36","author":"Pelsers","year":"2003","journal-title":"Clin. Biochem"},{"key":"key\n\t\t\t\t20180403133401_CIT0023","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0301-6226(97)00057-2","article-title":"Factors influencing the structure and function of the small intestine in the weaned pig: a review","volume":"51","author":"Pluske","year":"1997","journal-title":"Livest. Prod. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0024","doi-asserted-by":"crossref","first-page":"e88335","DOI":"10.1371\/journal.pone.0088335","article-title":"Serum amino acids profile and the beneficial effects of L-arginine or L-glutamine supplementation in dextran sulfate sodium colitis","volume":"9","author":"Ren","year":"2014","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180403133401_CIT0025","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/jn\/135.7.1609","article-title":"Nutritional and functional importance of intestinal sulfur amino acid metabolism","volume":"135","author":"Shoveller","year":"2005","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t20180403133401_CIT0026","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jnutbio.2010.03.012","article-title":"Dietary L-arginine supplementation differentially regulates expression of fat-metabolic genes in porcine adipose tissue and skeletal muscle","volume":"22","author":"Tan","year":"2011","journal-title":"J. Nutr. Biochem"},{"key":"key\n\t\t\t\t20180403133401_CIT0027","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/asj.12399","article-title":"Influence of weaning age on the villous height and disaccharidase activities in the porcine small intestine","volume":"87","author":"Tsukahara","year":"2016","journal-title":"Anim. Sci. J"},{"key":"key\n\t\t\t\t20180403133401_CIT0028","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s10620-008-0490-9","article-title":"Effect of fat feeding on pro-oxidant and anti-oxidant enzyme systems in rat intestine: possible role in the turnover of enterocytes","volume":"54","author":"Turan","year":"2009","journal-title":"Dig. Dis. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0029","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1093\/jn\/128.6.947","article-title":"Weaning and the weanling diet influence the villous height and crypt depth in the small intestine of pigs and alter the concentrations of short-chain fatty acids in the large intestine and blood","volume":"128","author":"van Beers-Schreurs","year":"1998","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t20180403133401_CIT0030","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.2527\/jas.2012-5795","article-title":"Dietary supplementation with N-carbamylglutamate increases the expression of intestinal AA transporters in weaned Huanjiang mini-pig piglets","volume":"91","author":"Yang","year":"2013","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180403133401_CIT0031","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1631\/jzus.B1500192","article-title":"Effects of yeast products on the intestinal morphology, barrier function, cytokine expression, and antioxidant system of weaned piglets","volume":"17","author":"Yang","year":"2016","journal-title":"J. Zhejiang Univ. Sci. B"},{"key":"key\n\t\t\t\t20180403133401_CIT0032","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0301-6226(01)00214-7","article-title":"Effect of supplementing diets containing hulless barley varieties having different levels of non-starch polysaccharides with \u03b2-glucanase and xylanase on the physiological status of gastrointestinal tract and nutrient digestibility of weaned pigs","volume":"71","author":"Yin","year":"2001","journal-title":"Livest. Prod. Sci"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jas\/article-pdf\/96\/3\/1130\/24531849\/skx003.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,3]],"date-time":"2018-04-03T14:31:09Z","timestamp":1522765869000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/96\/3\/1130\/4823829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,24]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,1,24]]},"published-print":{"date-parts":[[2018,4,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jas\/skx003","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,3]]},"published":{"date-parts":[[2018,1,24]]}}}