{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:24:27Z","timestamp":1787009067141,"version":"build-2736575974"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"name":"AFRINIFA","award":["2011-68004-30336"],"award-info":[{"award-number":["2011-68004-30336"]}]},{"name":"AFRINIFA","award":["2016-67017-2474"],"award-info":[{"award-number":["2016-67017-2474"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,6]]},"DOI":"10.1093\/jas\/skx074","type":"journal-article","created":{"date-parts":[[2018,1,28]],"date-time":"2018-01-28T23:46:54Z","timestamp":1517183214000},"page":"462-472","source":"Crossref","is-referenced-by-count":17,"title":["Impact of Mycoplasma hyopneumoniae and Lawsonia intracellularis on the performance of pigs divergently selected for feed efficiency"],"prefix":"10.1093","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8025-9690","authenticated-orcid":false,"given":"Emma T","family":"Helm","sequence":"first","affiliation":[{"name":"Department of Animal Science, Iowa State University Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda C","family":"Outhouse","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Iowa State University Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent J","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack C M","family":"Dekkers","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Iowa State University Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M","family":"Lonergan","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Iowa State University Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy M","family":"Rauw","sequence":"additional","affiliation":[{"name":"Departamento de Mejora Gen\u00e9tica Animal, Instituto Nacional de Investigaci\u00f3n y Tecnolog\u00eda Agraria y Alimentaria Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas K","family":"Gabler","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Iowa State University Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"key\n\t\t\t\t20180917114203_CIT0001","first-page":"1344","article-title":"Effects of ad libitum and restricted feeding on early production performance and body composition of Yorkshire pigs selected for reduced residual feed intake","volume":"5","author":"Boddicker","year":"2011","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0002","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.vetmic.2010.05.021","article-title":"Evaluation of Lawsonia intracellularis infection in a group of pigs in a subclinically affected herd from weaning to slaughter","volume":"146","author":"Brandt","year":"2010","journal-title":"Vet. Microbiol"},{"key":"key\n\t\t\t\t20180917114203_CIT0003","doi-asserted-by":"crossref","first-page":"204","DOI":"10.54846\/jshap\/886","article-title":"Correlation of Lawsonia intracellularis semi-quantitative fecal polymerase chain reaction assay results with the presence of histologic lesions of proliferative enteropathy and positive immunohistochemical staining","volume":"23","author":"Burrough","year":"2015","journal-title":"JSHAP"},{"key":"key\n\t\t\t\t20180917114203_CIT0004","doi-asserted-by":"crossref","first-page":"287","DOI":"10.2527\/jas.2007-0396","article-title":"Selection response and genetic parameters for residual feed intake in Yorkshire swine","volume":"86","author":"Cai","year":"2008","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0005","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.rvsc.2011.01.010","article-title":"Florfenicol feed supplemented decrease the clinical effects of Mycoplasma hyopneumoniae experimental infection in swine in Mexico","volume":"92","author":"Ciprian","year":"2012","journal-title":"Res. Vet. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0006","first-page":"10","article-title":"The effect of Mycoplasma hyopneumoniae infection on growth in pigs with or without environmental constraints","volume":"1","author":"Clark","year":"1993","journal-title":"JSHAP"},{"key":"key\n\t\t\t\t20180917114203_CIT0007","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.physbeh.2016.03.003","article-title":"Daily feeding regimen impacts pig growth and behavior","volume":"159","author":"Colpoys","year":"2016","journal-title":"Physiol. Behav"},{"key":"key\n\t\t\t\t20180917114203_CIT0008","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2527\/jas.2016.1000","article-title":"Nursery pig growth performance and tissue accretion modulation due to porcine epidemic diarrhea virus or porcine deltacoronavirus challenge","volume":"95","author":"Curry","year":"2017","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0009","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.livsci.2015.04.014","article-title":"Response of pigs divergently selected for residual feed intake to experimental infection with the PRRS virus","volume":"177","author":"Dunkelberger","year":"2015","journal-title":"Livest. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0010","article-title":"Use of computed tomography in live pigs to measure the impact of pneumonia on carcass composition","volume-title":"Paterson, J. E., Barker, J. A., editors, Manipulating pig production XI. ISBN: 9780957722637. Werribee, Australia: Australasian Pig Science Association; p. 60","author":"Eamens","year":"2007"},{"key":"key\n\t\t\t\t20180917114203_CIT0011","doi-asserted-by":"crossref","first-page":"384","DOI":"10.2527\/2002.802384x","article-title":"Growth performance and whole-body composition of pigs experimentally infected with Mycoplasma hyopneumoniae","volume":"80","author":"Escobar","year":"2002","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0012","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1093\/jn\/134.11.3047","article-title":"Decreased protein accretion in pigs with viral and bacterial pneumonia is associated with increased myostatin expression in muscle","volume":"134","author":"Escobar","year":"2004","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t20180917114203_CIT0013","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1751-0813.1991.tb03114.x","article-title":"Suboptimal growth associated with porcine intestinal adenomatosis in pigs in nutritional studies","volume":"68","author":"Gogolewski","year":"1991","journal-title":"Aust. Vet. J"},{"key":"key\n\t\t\t\t20180917114203_CIT0014","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.2527\/jas.2012-5894","article-title":"Divergent genetic selection for residual feed intake impacts mitochondria reactive oxygen species production in pigs","volume":"91","author":"Grubbs","year":"2013","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0015","doi-asserted-by":"crossref","first-page":"164","DOI":"10.2527\/jas.53855","article-title":"Improved nutrient digestibility and retention partially explains feed efficiency gains in pigs selected for low residual feed intake","volume":"90","author":"Harris","year":"2012","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0016","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3920\/978-90-8686-756-1_10","article-title":"Fueling the immune response: what\u2019s the cost","volume-title":"Feed efficiency in swine","author":"Johnson","year":"2012"},{"key":"key\n\t\t\t\t20180917114203_CIT0017","first-page":"1653","article-title":"Effect of inflammation stimulation on energy and nutrient utilization in piglets selected for low and high residual feed intake","volume":"9","author":"Labussi\u00e8re","year":"2015","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0018","first-page":"811","article-title":"Proliferative enteropathy","volume-title":"Diseases of swine","author":"McOrist","year":"2012"},{"key":"key\n\t\t\t\t20180917114203_CIT0019","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1136\/vr.140.22.579","article-title":"Estimate of direct financial losses due to porcine proliferative enteropathy","volume":"140","author":"McOrist","year":"1997","journal-title":"Vet. Rec"},{"key":"key\n\t\t\t\t20180917114203_CIT0020","first-page":"615","article-title":"Treatment and prevention of porcine proliferative enteropathy with oral tiamulin","volume":"139","author":"McOrist","year":"1996","journal-title":"Vet. Rec"},{"key":"key\n\t\t\t\t20180917114203_CIT0021","doi-asserted-by":"crossref","first-page":"563","DOI":"10.2527\/jas.2015-9445","article-title":"Metabolic response to an inflammatory challenge in pigs divergently selected for residual feed intake","volume":"94","author":"Merlot","year":"2016","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0022","doi-asserted-by":"crossref","first-page":"56","DOI":"10.2460\/javma.231.1.56","article-title":"Mechanisms of porcine diarrheal disease","volume":"231","author":"Moeser","year":"2007","journal-title":"J. Am. Vet. Med. Assoc"},{"key":"key\n\t\t\t\t20180917114203_CIT0023","volume-title":"Nutrient requirements of swine: eleventh revised edition","author":"National Research Council","year":"2012"},{"key":"key\n\t\t\t\t20180917114203_CIT0024","doi-asserted-by":"crossref","first-page":"137","DOI":"10.54846\/jshap\/697","article-title":"Subclinical ileitis: diagnostic and performance parameters in a multi-dose mucosal homogenate challenge model","volume":"20","author":"Paradis","year":"2012","journal-title":"JSHAP"},{"key":"key\n\t\t\t\t20180917114203_CIT0025","doi-asserted-by":"crossref","first-page":"233","DOI":"10.2527\/jas.53976","article-title":"Effect of immune system stimulation and divergent selection for residual feed intake on digestive capacity of the small intestine in growing pigs","volume":"90","author":"Rakhshandeh","year":"2012","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0026","first-page":"240","article-title":"Physiological consequences of selection for increased performance","volume":"17","author":"Rauw","year":"2007","journal-title":"Proc. Assoc. Advmt. Anim. Breed. Genet"},{"key":"key\n\t\t\t\t20180917114203_CIT0027","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0301-6226(98)00147-X","article-title":"Undesirable side effects of selection for high production efficiency in farm animals: a review","volume":"56","author":"Rauw","year":"1998","journal-title":"Livest. Prod. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0028","first-page":"7","article-title":"The effects of vaccinating pigs for mycoplasmal pneumonia in a swine herd affected by enzootic pneumonia","volume":"2","author":"Scheidt","year":"1994","journal-title":"JSHAP"},{"key":"key\n\t\t\t\t20180917114203_CIT0029","doi-asserted-by":"crossref","first-page":"480","DOI":"10.2527\/tas2017.0054","article-title":"Porcine Reproductive and Respiratory Syndrome virus reduces feed efficiency, digestibility and lean tissue accretion in grow-finish pigs","volume":"1","author":"Schweer","year":"2017","journal-title":"Transl. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0030","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.tvjl.2008.02.020","article-title":"Current perspectives on the diagnosis and epidemiology of Mycoplasma hyopneumoniae infection","volume":"181","author":"Sibila","year":"2009","journal-title":"Vet. J"},{"key":"key\n\t\t\t\t20180917114203_CIT0031","doi-asserted-by":"crossref","first-page":"192","DOI":"10.2527\/jas.2010-2861","article-title":"Effects of selection for decreased residual feed intake on composition and quality of fresh pork","volume":"89","author":"Smith","year":"2011","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0032","doi-asserted-by":"crossref","first-page":"627","DOI":"10.2460\/javma.1991.198.04.627","article-title":"Performance measured in pigs with pneumonia and housed in different environments","volume":"198","author":"Straw","year":"1991","journal-title":"J. Am. Vet. Med. Assoc"},{"key":"key\n\t\t\t\t20180917114203_CIT0033","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0301-6226(03)00077-0","article-title":"Accuracy of dual energy X-ray absorptiometry (DXA), weight and P2 back fat to predict whole body and carcass composition in pigs within and across experiments","volume":"84","author":"Suster","year":"2003","journal-title":"Livest. Prod. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0034","first-page":"779","article-title":"Mycoplasmosis","volume-title":"Diseases of swine","author":"Thacker","year":"2012"},{"key":"key\n\t\t\t\t20180917114203_CIT0035","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1093\/ps\/83.11.1904","article-title":"Residual feed intake and its effect on Salmonella enteritidis infection in growing layer hens","volume":"83","author":"Van Eerden","year":"2004","journal-title":"Poult. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0036","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.2527\/1997.7592472x","article-title":"Effect of chronic immune system activation on body nitrogen retention, partial efficiency of lysine utilization, and lysine needs of pigs","volume":"75","author":"Williams","year":"1997","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0037","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.2527\/1997.7592463x","article-title":"Effect of chronic immune system activation on the rate, efficiency, and composition of growth and lysine needs of pigs fed from 6 to 27 kg","volume":"75","author":"Williams","year":"1997","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0038","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.2527\/1997.7592481x","article-title":"Effect of level of chronic immune system activation on the growth and dietary lysine needs of pigs fed from 6 to 112 kg","volume":"75","author":"Williams","year":"1997","journal-title":"J. Anim. Sci"},{"key":"key\n\t\t\t\t20180917114203_CIT0039","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1071\/ANv55n12Ab027","article-title":"Rapid changes occur in feed efficiency after infection with Mycoplasma hyopneumoniae and Pasteurella multocida","volume":"55","author":"Wyburn","year":"2015","journal-title":"Anim. Prod. Sci"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jas\/article-pdf\/96\/2\/462\/25741932\/skx074.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T21:33:39Z","timestamp":1751232819000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/96\/2\/462\/4827893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,29]]},"references-count":39,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,1,29]]},"published-print":{"date-parts":[[2018,3,6]]}},"URL":"https:\/\/doi.org\/10.1093\/jas\/skx074","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,2]]},"published":{"date-parts":[[2018,1,29]]}}}