{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:45:15Z","timestamp":1787319915699,"version":"build-2736575974"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T00:00:00Z","timestamp":1533772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,21]]},"DOI":"10.1093\/jas\/sky327","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T04:13:34Z","timestamp":1533788014000},"page":"4743-4754","source":"Crossref","is-referenced-by-count":40,"title":["Effects of dietary pectin on the profile and transport of intestinal bile acids in young pigs"],"prefix":"10.1093","volume":"96","author":[{"given":"Wei","family":"Fang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingshi","family":"Meng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weida","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan Kun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Xie","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfu","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,8,9]]},"reference":[{"key":"key\n\t\t\t\t2018112109130888000_CIT0001","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/S0039-128X(96)00119-5","article-title":"Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification","volume":"61","author":"Aldini","year":"1996","journal-title":"Steroids"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0002","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1007\/s11095-007-9289-1","article-title":"Bile acid transporters: structure, function, regulation and pathophysiological implications","volume":"24","author":"Alrefai","year":"2007","journal-title":"Pharm. Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0003","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1210\/en.2015-1321","article-title":"Bile acids trigger GLP-1 release predominantly by accessing basolaterally located G protein-coupled bile acid receptors","volume":"156","author":"Brighton","year":"2015","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0004","volume-title":"Nutrient requirements of swine","author":"Council","year":"2012"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0005","doi-asserted-by":"crossref","first-page":"6960","DOI":"10.1074\/jbc.M412752200","article-title":"The heteromeric organic solute transporter alpha-beta, ostalpha-ostbeta, is an ileal basolateral bile acid transporter","volume":"280","author":"Dawson","year":"2005","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0006","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1194\/jlr.R054114","article-title":"Intestinal transport and metabolism of bile acids","volume":"56","author":"Dawson","year":"2015","journal-title":"J. Lipid Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0007","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1194\/jlr.R900012-JLR200","article-title":"Bile acid transporters","volume":"50","author":"Dawson","year":"2009","journal-title":"J. Lipid Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0008","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.bbalip.2007.09.003","article-title":"Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene","volume":"1771","author":"Duane","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0009","doi-asserted-by":"crossref","first-page":"e00287","DOI":"10.1002\/prp2.287","article-title":"Influence of age on intestinal bile acid transport in C57BL\/6 mice","volume":"5","author":"Gao","year":"2017","journal-title":"Pharmacol. Res. Perspect"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0010","doi-asserted-by":"crossref","first-page":"e0157427","DOI":"10.1371\/journal.pone.0157427","article-title":"Molecular properties of guar gum and pectin modify cecal bile acids, microbiota, and plasma lipopolysaccharide-binding protein in rats","volume":"11","author":"Ghaffarzadegan","year":"2016","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0011","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S1097-2765(00)00051-4","article-title":"A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis","volume":"6","author":"Goodwin","year":"2000","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0012","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.molmet.2016.05.012","article-title":"Microbial regulation of GLP-1 and L-cell biology","volume":"5","author":"Greiner","year":"2016","journal-title":"Mol. Metab"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0013","doi-asserted-by":"crossref","first-page":"4227","DOI":"10.1096\/fj.201600465R","article-title":"Reduction in circulating bile acid and restricted diffusion across the intestinal epithelium are associated with a decrease in blood cholesterol in the presence of oat \u03b2-glucan","volume":"30","author":"Gunness","year":"2016","journal-title":"Faseb J"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0014","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/mnfr.201500686","article-title":"Circulating triglycerides and bile acids are reduced by a soluble wheat arabinoxylan via modulation of bile concentration and lipid digestion rates in a pig model","volume":"60","author":"Gunness","year":"2016","journal-title":"Mol. Nutr. Food Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0015","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1152\/physrev.00034.2006","article-title":"The physiology of glucagon-like peptide 1","volume":"87","author":"Holst","year":"2007","journal-title":"Physiol. Rev"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0016","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1194\/jlr.D047506","article-title":"A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS","volume":"55","author":"Kakiyama","year":"2014","journal-title":"J. Lipid Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0017","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.bbrc.2005.01.139","article-title":"Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1","volume":"329","author":"Katsuma","year":"2005","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0018","doi-asserted-by":"crossref","first-page":"G476","DOI":"10.1152\/ajpgi.00430.2005","article-title":"The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes","volume":"290","author":"Landrier","year":"2006","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0019","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1097-2765(00)00050-2","article-title":"Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors","volume":"6","author":"Lu","year":"2000","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0020","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/jn\/125.3.454","article-title":"Cholesterol 7 alpha-hydroxylase activity is increased by dietary modification with psyllium hydrocolloid, pectin, cholesterol and cholestyramine in rats","volume":"125","author":"Matheson","year":"1995","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0021","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1093\/jn\/124.8.1161","article-title":"Dietary psyllium hydrocolloid and pectin increase bile acid pool size and change bile acid composition in rats","volume":"124","author":"Matheson","year":"1994","journal-title":"J. Nutr"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0022","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11745-016-4125-1","article-title":"Determination of bile acids in piglet bile by solid phase extraction and liquid chromatography-electrospray tandem mass spectrometry","volume":"51","author":"Mi","year":"2016","journal-title":"Lipids"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0023","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.bbrc.2013.11.126","article-title":"SREBP-2 negatively regulates FXR-dependent transcription of FGF19 in human intestinal cells","volume":"443","author":"Miyata","year":"2014","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0024","doi-asserted-by":"crossref","first-page":"e005","DOI":"10.1621\/nrs.08005","article-title":"Deciphering the nuclear bile acid receptor FXR paradigm","volume":"8","author":"Modica","year":"2010","journal-title":"Nucl. Recept. Signal"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0025","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/hep.20295","article-title":"Bile acid-induced negative feedback regulation of the human ileal bile acid transporter","volume":"40","author":"Neimark","year":"2004","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0026","doi-asserted-by":"crossref","first-page":"27703","DOI":"10.1074\/jbc.M302128200","article-title":"Farnesoid X receptor regulates bile acid-amino acid conjugation","volume":"278","author":"Pircher","year":"2003","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0027","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1093\/chromsci\/bmu167","article-title":"Rapid determination of bile acids in bile from various mammals by reversed-phase ultra-fast liquid chromatography","volume":"53","author":"Si","year":"2015","journal-title":"J. Chromatogr. Sci"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0028","doi-asserted-by":"crossref","first-page":"G996","DOI":"10.1152\/ajpgi.90343.2008","article-title":"Beta-klotho and FGF-15\/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes","volume":"295","author":"Sinha","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0029","article-title":"Effects of pectin on fermentation characteristics, carbohydrate utilization, and microbial community composition in the gastrointestinal tract of weaning pigs","volume":"61:1\u201310","author":"Tian","year":"2017","journal-title":"Mol. Nutr. Food Res"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S1050-1738(00)00043-8","article-title":"FXR, a bile acid receptor and biological sensor","volume":"10","author":"Tu","year":"2000","journal-title":"Trends Cardiovasc. Med"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0031","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cmet.2016.05.005","article-title":"Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism","volume":"24","author":"Wahlstr\u00f6m","year":"2016","journal-title":"Cell Metab"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0032","doi-asserted-by":"crossref","first-page":"4644","DOI":"10.1039\/C6FO01406B","article-title":"Dietary fibers influence the intestinal scfas and plasma metabolites profiling in growing pigs","volume":"7","author":"Wu","year":"2016","journal-title":"Food Funct"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0033","article-title":"Spatial heterogeneity and co-occurrence of mucosal and luminal microbiome across swine intestinal tract","volume":"9","author":"Zhang","year":"2018","journal-title":"Front Microbiol"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0034","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s11745-017-4258-x","article-title":"Pectin penta-oligogalacturonide suppresses intestinal bile acids absorption and downregulates the FXR-FGF15 axis in high-cholesterol fed mice","volume":"52","author":"Zhu","year":"2017","journal-title":"Lipids"},{"key":"key\n\t\t\t\t2018112109130888000_CIT0035","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cbi.2017.05.018","article-title":"Pectin penta-oligogalacturonide reduces cholesterol accumulation by promoting bile acid biosynthesis and excretion in high-cholesterol-fed mice","volume":"272","author":"Zhu","year":"2017","journal-title":"Chem. Biol. Interact"}],"container-title":["Journal of Animal Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jas\/article-pdf\/96\/11\/4743\/26675012\/sky327.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T04:06:32Z","timestamp":1751774792000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jas\/article\/96\/11\/4743\/5068405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,9]]},"references-count":35,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,8,9]]},"published-print":{"date-parts":[[2018,11,21]]}},"URL":"https:\/\/doi.org\/10.1093\/jas\/sky327","relation":{},"ISSN":["0021-8812","1525-3163"],"issn-type":[{"value":"0021-8812","type":"print"},{"value":"1525-3163","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,11]]},"published":{"date-parts":[[2018,8,9]]}}}