{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:38:55Z","timestamp":1788997135901,"version":"build-2803163510"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The historical practice of brewing poppy tea for its opioid-like effects is reoccurring with modern-day substance users. We present four postmortem cases with toxicology results that serve as case studies for the potential hazards of poppy tea ingestion. There is limited information regarding the risks of this practice due to the variability of the morphine content of the opium exuded from the plant. While internet tea recipes offer guidance, differences in poppy cultivation, washing, and infusing time are some of the reasons why the beverage may contain inconsistent and clinically significant alkaloid concentrations for each preparation. Variability in opioid tolerance along with additional drugs taken will impact the overall degree of toxicity experienced from the opiates in the tea. Advancements in the genetic modification of the poppy plant could greatly alter the ratio of alkaloids seen in biological fluids and will be highly dependent on the source of the poppy product. The blood concentrations of free morphine and free codeine in cases 1\u20133 where the toxicity from the tea was considered the primary cause of death were 0.94 and 0.11\u00a0mg\/L, 0.62 and 0.034\u00a0mg\/L, and 0.16 and 0.010\u00a0mg\/L, respectively. The urine concentrations of morphine and codeine were 13 and 0.94\u00a0mg\/L in case 1 and 16 and 1.6\u00a0mg\/L in case 2, respectively. The opium alkaloids thebaine and laudanosine were identified qualitatively by our routine organic base\/neutral drug detection procedure.<\/jats:p>","DOI":"10.1093\/jat\/bkaa093","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T19:11:26Z","timestamp":1596222686000},"page":"734-740","source":"Crossref","is-referenced-by-count":14,"title":["Death from Poppy Tea Consumption"],"prefix":"10.1093","volume":"44","author":[{"given":"Sandra C","family":"Bishop-Freeman","sequence":"first","affiliation":[{"name":"Office of the Chief Medical Examiner, 4312 District Dr, Raleigh, NC, 27607, USA"},{"name":"UNC Department of Pathology and Laboratory Medicine, 160 Medical Dr., Chapel Hill, NC, 27559, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Fox","sequence":"additional","affiliation":[{"name":"Office of the Chief Medical Examiner, 4312 District Dr, Raleigh, NC, 27607, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth E","family":"Winecker","sequence":"additional","affiliation":[{"name":"Center for Forensic Sciences, RTI International, 3040 E Cornwallis Rd., Research Triangle Park, NC, 27709, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason S","family":"Hudson","sequence":"additional","affiliation":[{"name":"Office of the Chief Medical Examiner, 4312 District Dr, Raleigh, NC, 27607, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,10,12]]},"reference":[{"key":"2020101206443613200_ref1","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1021\/acschemneuro.8b00459","article-title":"DARK classics in chemical neuroscience: Opium, a historical perspective","volume":"9","author":"Presley","year":"2018","journal-title":"ACS Chemical 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