{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T22:43:20Z","timestamp":1780958600015,"version":"3.54.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The emergence of novel designer benzodiazepines continues to be a public health concern. Flualprazolam is one of these drugs. It was initially identified in 2017. User forums suggest it is slightly more potent than alprazolam and has longer-lasting central nervous system depressant effects. Here we report a simple, sensitive liquid chromatography\u2013tandem mass spectrometry method for flualprazolam and report a series of nine cases in which flualprazolam was quantified. As is typical of forensic toxicology in the twenty-first century, all the cases had more than one drug present. None of the deaths could be directly attributed to flualprazolam alone, but all were likely due to a combination of sedative drugs. However, this paper still adds to the data available to allow interpretation of postmortem flualprazolam concentrations.<\/jats:p>","DOI":"10.1093\/jat\/bkaa098","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T11:11:04Z","timestamp":1596539464000},"page":"410-416","source":"Crossref","is-referenced-by-count":27,"title":["Quantification of Flualprazolam in Blood by LC\u2013MS-MS: A Case Series of Nine Deaths"],"prefix":"10.1093","volume":"45","author":[{"given":"Kathleen","family":"Rice","sequence":"first","affiliation":[{"name":"Toxicology Unit Heartlands Hospital, Birmingham, West Midlands, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Hikin","sequence":"additional","affiliation":[{"name":"Toxicology Unit University Hospital Leicester, Leicester, Leicestershire, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Lawson","sequence":"additional","affiliation":[{"name":"Toxicology Unit Heartlands Hospital, Birmingham, West Midlands, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R","family":"Smith","sequence":"additional","affiliation":[{"name":"Toxicology Unit University Hospital Leicester, Leicester, Leicestershire, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Morley","sequence":"additional","affiliation":[{"name":"Toxicology Unit University Hospital Leicester, Leicester, Leicestershire, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"2021041212125566900_R1","volume-title":"U.S. Patent No. 3,987,052","author":"Hester, 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